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Picaridin  (Synonyms: Lcaridin)

製品番号: HY-116144 純度: 98.30%
COA 取扱説明書 Technical Support

Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial, anticandidal and antifungal properties.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Picaridin

Picaridin 構造式

CAS 番号 : 119515-38-7

容量 価格（税別） 在庫状況 数量
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 27 在庫あり
Solution
10 mM * 1 mL in DMSO USD 27 在庫あり
Liquid
500 mg $25 在庫あり
1 g $40 在庫あり
5 g $80 在庫あり
10 g $120 在庫あり
25 g $215 在庫あり
50 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Based on 3 publication(s) in Google Scholar

Other Forms of Picaridin:

Picaridin 関連抗体

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 純度とドキュメンテーション

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製品説明

Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial, anticandidal and antifungal properties[1][2][3][4].

体外実験

Picaridin (10-20%) repels Aedes aegypti with a protection duration of 351.5-410.4 min[2].
Picaridin (10%-40%, 24-72 h) exhibits considerable antibacterial, anticandidal and antifungal properties, with MICs of 0.31-2.5% (v/v), MBCs/MFCs of 0.62- >2.5% (v/v)[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Picaridin 関連抗体

Cell Viability Assay[3]

Cell Line: P. aeruginosa ATCC 27853, E. coli ATCC 25922, K. pneumoniae ATCC 13883, S. aureus ATCC 29213, Y. enterocolitica ATCC 27729, B. cereus ATCC 33019, P. vulgaris ATCC 13315, S. flexneri ATCC 12022, C. albicans, A. niger, B. cinerea, P. vinaceum
Concentration: 10, 20, 30 and 40 % (v/v)
Incubation Time: 24 h for bacterial strains, 48 h for yeast, 72 h for fungi isolates
Result: Had stronger antibacterial effect than DEET.
Displayed moderate antifungal characteristics that required at least the concentration of 2.5 % (v/v) for a complete inhibitory effect against yeast and fungi.
体内実験

Picaridin (p.o., dermal, inhalation) shows very low acute toxicity in rats, rabbits and pigs, regardless of the route of administration[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
分子量

229.32

分子式

C12H23NO3
CAS 番号
Appearance

Liquid (Density: 1.041±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(N1C(CCCC1)CCO)OC(CC)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外: 

DMSO : 250 mg/mL (1090.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3607 mL 21.8036 mL 43.6072 mL
5 mM 0.8721 mL 4.3607 mL 8.7214 mL
10 mM 0.4361 mL 2.1804 mL 4.3607 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.08 mg/mL (9.07 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.08 mg/mL (9.07 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
純度とドキュメンテーション

純度: 99.25%

COA (248 KB) HNMR (204 KB) LCMS (134 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.3607 mL 21.8036 mL 43.6072 mL 109.0180 mL
5 mM 0.8721 mL 4.3607 mL 8.7214 mL 21.8036 mL
10 mM 0.4361 mL 2.1804 mL 4.3607 mL 10.9018 mL
15 mM 0.2907 mL 1.4536 mL 2.9071 mL 7.2679 mL
20 mM 0.2180 mL 1.0902 mL 2.1804 mL 5.4509 mL
25 mM 0.1744 mL 0.8721 mL 1.7443 mL 4.3607 mL
30 mM 0.1454 mL 0.7268 mL 1.4536 mL 3.6339 mL
40 mM 0.1090 mL 0.5451 mL 1.0902 mL 2.7254 mL
50 mM 0.0872 mL 0.4361 mL 0.8721 mL 2.1804 mL
60 mM 0.0727 mL 0.3634 mL 0.7268 mL 1.8170 mL
80 mM 0.0545 mL 0.2725 mL 0.5451 mL 1.3627 mL
100 mM 0.0436 mL 0.2180 mL 0.4361 mL 1.0902 mL
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Picaridin Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Picaridin119515-38-7LcaridinParasiteEnvironmental PollutantsEnvironmental ContaminantsrepellentDEETmosquitoesinsectolfactorysensory ,neuronsodorantreceptorproteinsInhibitorinhibitorinhibit

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