1. Metabolic Enzyme/Protease
  2. Cytochrome P450
  3. Prothipendyl hydrochloride

Prothipendyl hydrochloride is a tricyclic azaphenothiazine neuroleptic agent. Prothipendyl hydrochloride is a substrate of the CYP isozymes CYP1A2, CYP2D6, CYP2C19 and CYP3A4. Prothipendyl hydrochloride has sedating and psychomotorically damping effects. Prothipendyl hydrochloride can be used for psychomotoric agitation, sleep disorder and anxiety research .

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Prothipendyl hydrochloride

Prothipendyl hydrochloride Estructura química

No. CAS : 1225-65-6

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg   Obtener un presupuesto  
50 mg   Obtener un presupuesto  

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Descripciòn

Prothipendyl hydrochloride is a tricyclic azaphenothiazine neuroleptic agent. Prothipendyl hydrochloride is a substrate of the CYP isozymes CYP1A2, CYP2D6, CYP2C19 and CYP3A4. Prothipendyl hydrochloride has sedating and psychomotorically damping effects. Prothipendyl hydrochloride can be used for psychomotoric agitation, sleep disorder and anxiety research [1].

Peso molecular

321.87

Fòrmula

C16H20ClN3S

No. CAS
Appearance

Solid

Color

Light yellow to yellow

SMILES

CN(C)CCCN1C2=C(C=CC=C2)SC3=CC=CN=C13.Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (310.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1068 mL 15.5342 mL 31.0684 mL
5 mM 0.6214 mL 3.1068 mL 6.2137 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1068 mL 15.5342 mL 31.0684 mL 77.6711 mL
5 mM 0.6214 mL 3.1068 mL 6.2137 mL 15.5342 mL
10 mM 0.3107 mL 1.5534 mL 3.1068 mL 7.7671 mL
15 mM 0.2071 mL 1.0356 mL 2.0712 mL 5.1781 mL
20 mM 0.1553 mL 0.7767 mL 1.5534 mL 3.8836 mL
25 mM 0.1243 mL 0.6214 mL 1.2427 mL 3.1068 mL
30 mM 0.1036 mL 0.5178 mL 1.0356 mL 2.5890 mL
40 mM 0.0777 mL 0.3884 mL 0.7767 mL 1.9418 mL
50 mM 0.0621 mL 0.3107 mL 0.6214 mL 1.5534 mL
60 mM 0.0518 mL 0.2589 mL 0.5178 mL 1.2945 mL
80 mM 0.0388 mL 0.1942 mL 0.3884 mL 0.9709 mL
100 mM 0.0311 mL 0.1553 mL 0.3107 mL 0.7767 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
Prothipendyl hydrochloride
Cat. No.:
HY-116780A
Cantidad:
MCE Japan Authorized Agent: