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Results for "

4(1H

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Angiotensin Receptor (2) Autophagy (4) Bacterial (7) Biochemical Assay Reagents (6) DNA/RNA Synthesis (1) Drug Intermediate (7) Drug Metabolite (1) Endogenous Metabolite (1) HCV (2) Histone Methyltransferase (4) HSV (1) Isotope-Labeled Compounds (9) MOFs (66) Monoamine Oxidase (2) Nucleoside Antimetabolite/Analog (12) PROTAC Linkers (1) Reactive Oxygen Species (ROS) (1) Reference Standards (10)
By Research Areas:	Cancer (15) Cardiovascular Disease (2) Endocrinology (1) Infection (11) Metabolic Disease (2) Neurological Disease (3)
Oligonucleotides:	Nucleoside Analogs (10) Cytidine (2)

128

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W037619

*Pteridine-2,4(1H,3H)-dione*	Biochemical Assay Reagents	Neurological Disease Cancer
Pteridine-2,4 (1H,3H)-dione is a pteridine derivative (xanthopterin) and a sulfur-containing pteridine compound (2,4-dimercaptopyrimidine). Pteridine-2,4 (1H,3H)-dione possesses metal-binding ability, and forms closed-shell (ionic) interactions with palladium via sulfur and nitrogen atoms. Pteridine-2,4 (1H,3H)-dione derivates can be used in studies related to neuroblastoma, glioma and breast cancer .

HY-W075276

4-(1H-Pyrazol-1-ylmethyl)benzoic acid	MOFs	Others
4-((1H-Pyrazol-1-yl)methyl)benzoic acid (4-(1H-pyrazol-1-ylmethyl)benzoic acid) is a metal-organic framework (MOF).

HY-W017713

*4-[4-(1H-Pyrazol-4-yl)phenyl]-1H-pyrazole* 1,4-Di(1H-pyrazol-4-yl)benzene	MOFs	Others
4-[4-(1H-Pyrazol-4-yl)phenyl]-1H-pyrazole (1,4-Di(1H-pyrazol-4-yl)benzene) is a metal-organic framework (MOF).

HY-W015462

LANA-IN-1 4-(1H-Imidazol-1-yl)aniline	HSV	Infection
LANA-IN-1 (compound 8) is an N-acetyl-derived LANA inhibitor with antiviral activity against herpesvirus. In fluorescence assays using the LANA probe LBS2, 1 mM LANA-IN-1 shows an inhibition rate of 32%. LANA-IN-1 may inhibit the interaction between LANA and the viral genome .

HY-W052191

4-(1H-Imidazol-2-yl)pyridine	MOFs	Others
4-(1H-Imidazol-2-yl)pyridine is a metal-organic framework (MOF).

HY-34840

*6-Hydrazinyl-3-methylpyrimidine-2,4(1H,3H)-dione*	Drug Intermediate	Others
6-Hydrazinyl-3-methylpyrimidine-2,4(1H,3H)-dione is a drug intermediate for synthesis of various active compounds.

HY-N9530

*1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone*	Acyltransferase Angiotensin Receptor Bacterial	Infection Cardiovascular Disease Metabolic Disease
1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, with IC₅₀s of 20.1 μM and 34.1 μM, respectively. 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows potent anti-Helicobacter pylori activity with the MIC of 10 μg/mL .

HY-W112721

1H,1'H-4,4'-Bipyrazole 4-(1H-Pyrazol-4-yl)-1H-pyrazole	MOFs	Others
1H,1'H-4,4'-Bipyrazole (4-(1H-Pyrazol-4-yl)-1H-pyrazole) is a metal-organic framework (MOF).

HY-78248

4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents	Others
4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-N1638

*1-Methyl-2-undecyl-4(1H)-quinolone*	Monoamine Oxidase	Neurological Disease
1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC₅₀ and K_i values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS .

HY-168698

*(4-(1H-1,2,3-Triazol-4-yl)phenyl)methanol*	PROTAC Linkers	Cancer
(4-(1H-1,2,3-Triazol-4-yl)phenyl)methanol is a PROTAC Linker. (4-(1H-1,2,3-Triazol-4-yl)phenyl)methanol can be used to synthesize PROTAC Setidegrasib (HY-148273) .

HY-N1637

*1-Methyl-2-pentyl-4(1H)-quinolinone*	Bacterial	Infection Cancer
1-Methyl-2-pentyl-4(1H)-quinolinone, a quinolone alkaloid isolated from the fruits of Evodia Rutaecarpa, possesses antibacterial and cytotoxic activities for cancer cells .

HY-N10456

*1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone*	Bacterial	Infection
1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone is a potent antibacterial agent with an MIC₅₀ value of 22 µM and an MIC₉₀ value of 50 µM for Helicobacter pyloriStrain 51. 1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone has the potential for the research of gastric and duodenal ulcers .

HY-N0968

*1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone*	Others	Others
1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone, as a colorless oil, is a quinolone alkaloid isolated from the fruit of Evodia rutaecarpa BENTHAM (Rutaceae) .

HY-W741652

2-(2-Chloroethyl-d4)-1H-isoindole-1,3-dione	Isotope-Labeled Compounds	Others
2-(2-Chloroethyl-d₄)-1H-isoindole-1,3-dione is the deuterium labeled 2-(2-Chloroethyl)isoindoline-1,3-dione (HY-W014424).

HY-N9520

*1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone*	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is an antagonist of angiotensin II receptor (IC₅₀=48.2 μM). Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is a quinolone alkaloid from Evodia rutaecarpa .

HY-N10907

4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-	Bacterial	Infection
4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- (compound 2) is a quinolone alkaloid that can be isolated from Cnidium. 4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- has methicillin-resistant Staphylococcus aureus (MRSA) activity, with MIC values of 32 μg/mL (ATCC 33591) and 16 μM/mL (ATCC 25923), respectively .

HY-154741S

*6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione-15N2*	Isotope-Labeled Compounds	Others
6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione- ¹⁵N₂ is ¹⁵N labeled (HY-154741).

HY-154325

*1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone*	Nucleoside Antimetabolite/Analog	Cancer
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152603

*2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone*	Nucleoside Antimetabolite/Analog	Others
2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152853

*3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione*	Nucleoside Antimetabolite/Analog	Others
3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154663

*1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione*	Nucleoside Antimetabolite/Analog	Cancer
1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W555382S

Pseudane IX-d4 2-Nonylquinolin-4(1H)-one-d₄	Isotope-Labeled Compounds HCV	Infection
Pseudane IX-d₄ (2-Nonylquinolin-4(1H)-one-d₄) is deuterium labeled Pseudane IX. Pseudane IX, a compound isolated from the leaves of Ruta angustifolia, has strong anti-HCV activity with an IC₅₀ value of 1.4 μg/mL. Pseudane IX reduces HCV RNA replication and viral protein synthesis levels .

HY-154335

*1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione*	Nucleoside Antimetabolite/Analog	Cancer
1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152676

*1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione*	Nucleoside Antimetabolite/Analog	Others
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-W751834

*6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione-13C3* NSC 99321-¹³C₃; 6-Amino-5-nitrouracil-¹³C₃	Isotope-Labeled Compounds	Others
6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione- ¹³C₃ (NSC 99321- ¹³C₃) is the ¹³C-labeled 6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione (HY-W016913).

HY-154652

*1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione*	Nucleoside Antimetabolite/Analog	Cancer
1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-154613

*(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione*	Nucleoside Antimetabolite/Analog	Cancer
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W768482

*2-Amino-6-hydroxypyrimidin-4(1H)-one-13C2* 2-Amino-6-hydroxy-1H-pyrimidin-4-one-¹³C₂; 2-Amino-4,6-dihydroxypyrimidine-¹³C₂	Isotope-Labeled Compounds	Others
2-Amino-6-hydroxypyrimidin-4(1H)-one- ¹³C₂ (2-Amino-6-hydroxy-1H-pyrimidin-4-one- ¹³C₂) is the ¹³C-labeled 2-Amino-6-hydroxypyrimidin-4(1H)-one (HY-Y0559).

HY-W023713

4-(1H-Pyrazol-5-yl)benzoic acid 4-(1H-Pyrazol-3-yl)benzoic acid	MOFs	Others
4-(1H-Pyrazol-5-yl)benzoic acid (4-(1H-Pyrazol-3-yl)benzoic acid) is a metal-organic framework (MOF).

HY-W112141

*N-(4-(1H-Imidazol-1-yl)phenyl)-4-(1H-imidazol-1-yl)-n-phenylaniline*	MOFs	Others
N-(4-(1H-Imidazol-1-yl)phenyl)-4-(1H-imidazol-1-yl)-n-phenylaniline is a metal-organic framework (MOF).

HY-W075288

4-(1H-Imidazol-1-yl)benzoic acid	MOFs	Others
4-(1H-Imidazol-1-yl)benzoic acid is a metal-organic framework (MOF).

HY-W051244

4-(1H-Pyrazol-3-yl)pyridine	MOFs	Others
4-(1H-Pyrazol-3-yl)pyridine is a metal-organic framework (MOF).

HY-W019096

4-(1H-Pyrazol-4-yl)pyridine	MOFs	Others
4-(1H-Pyrazol-4-yl)pyridine is a metal-organic framework (MOF).

HY-W090282

4-(1H-Imidazol-5-yl)pyridine	MOFs	Others
4-(1H-Imidazol-5-yl)pyridine is a metal-organic framework (MOF).

HY-W075074

*1,1,2,2-Tetrakis(4-(1H-imidazol-1-yl)phenyl)ethene* Tetrakis[4-(1H-Imidazol-1-yl)phenyl]ethylene	MOFs	Others
1,1,2,2-Tetrakis(4-(1H-imidazol-1-yl)phenyl)ethene(Tetrakis[4-(1H-Imidazol-1-yl)phenyl]ethylene) is a metal-organic framework (MOF).

HY-402321

*2-Octyl-4(1H)-quinolone*	Others	Others
2-Octyl-4(1H)-quinolone (Compound 14) is a quinolinone alkaloid that can be isolated from Ruta graveolens .

HY-W075237

*3-(4-(1H-Imidazol-1-yl)phenyl)-1H-pyrazole* 5-[4-(1H-Imidazol-1-yl)phenyl]-1H-pyrazole	MOFs	Others
3-(4-(1H-Imidazol-1-yl)phenyl)-1H-pyrazole (5-[4-(1H-Imidazol-1-yl)phenyl]-1H-pyrazole) is a metal-organic framework (MOF).

HY-W456450

4-((1H-Imidazol-1-yl)methyl)pyridine	MOFs	Others
4-((1H-Imidazol-1-yl)methyl)pyridine is a metal-organic framework (MOF).

HY-N1636

*1-Methyl-2-nonyl-4(1H)-quinolone*	Monoamine Oxidase	Neurological Disease
1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC₅₀ of 12.1 μM .

HY-W037619R

*Pteridine-2,4(1H,3H)-dione (Standard)*	Reference Standards Endogenous Metabolite	Metabolic Disease
Pteridine-2,4(1H,3H)-dione is an endogenous metabolite.

HY-W112186

*Tris(4-(1H-pyrazol-4-yl)phenyl)amine*	MOFs	Others
Tris(4-(1H-pyrazol-4-yl)phenyl)amine is a metal-organic framework (MOF).

HY-W456445

*Bis(4-(1H-imidazol-1-yl)phenyl)methanone*	MOFs	Others
Bis(4-(1H-imidazol-1-yl)phenyl)methanone is a metal-organic framework (MOF).

HY-W1049876

*2-Methoxy-4-(1H-pyrazol-4-yl)benzoic acid*	MOFs	Others
2-Methoxy-4-(1H-pyrazol-4-yl)benzoic acid is a metal-organic framework (MOF).

HY-N16462

*2-(2-Heptenyl)-3-methyl-4(1H)-quinolone*	Bacterial	Infection
2-(2-Heptenyl)-3-methyl-4(1H)-quinolone is a quinoline alkaloid found in Burkholderia sp. VY81. 2-(2-Heptenyl)-3-methyl-4(1H)-quinolone is promising for research of bacterial diseases in rice (e.g., soft rot) and other plant pathogens (e.g., Pythium ultimum, Fusarium oxysporum) .

HY-W112648

*2,4,6-Tris(4-(1H-pyrazol-4-yl)phenyl)-1,3,5-triazine* Tris[4-(1H-pyrazol-4-yl)phenyl]-1,3,5-triazine	MOFs	Others
2,4,6-Tris(4-(1H-pyrazol-4-yl)phenyl)-1,3,5-triazine(Tris[4-(1H-pyrazol-4-yl)phenyl]-1,3,5-triazine) is a metal-organic framework (MOF).

HY-W002957

4-(1H-1,2,4-triazol-1-yl)benzoic acid	MOFs	Others
4-(1H-1,2,4-triazol-1-yl)benzoic acid is a metal-organic framework (MOF).

HY-W543327

4-(1H-1,2,3-Triazol-5-yl)benzaldehyde	MOFs	Others
4-(1H-1,2,3-Triazol-5-yl)benzaldehyde is a metal-organic framework (MOF).

HY-W1049875

*2,6-Difluoro-4-(1H-pyrazol-4-yl)benzoic acid*	MOFs	Others
2,6-Difluoro-4-(1H-pyrazol-4-yl)benzoic acid is a metal-organic framework (MOF).

HY-W077690

*3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione*	Bacterial	Infection
3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione is an metal chelating agent and anti-bacterial agent. 3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione shows inhibitory activity against gram-positive and gram-negative bacterial strains .

Cat. No.	Product Name	Type

HY-W007695

1H-Imidazole-4-carboxylic acid

4-Imidazolecarboxylic acid

Biochemical Assay Reagents

1H-Imidazole-4-carboxylic acid is an organic compound containing an imidazole ring and a carboxyl group. 1H-Imidazole-4-carboxylic acid stabilizes specific forms of metal ions through coordination, thus influencing the progress of chemical reactions. 1H-Imidazole-4-carboxylic acid plays an important role in the hydrolysis of phosphate esters catalyzed by lanthanide metals. 1H-Imidazole-4-carboxylic acid can be used to modify dendrimers, changing the surface properties and catalytic performance of materials .

HY-I0314

1H-Pyrazole-4-boronic acid pinacol ester	Biochemical Assay Reagents
1H-Pyrazole-4-boronic acid pinacol ester is a drug intermediate that can be used for the synthesis of Mps1 kinase inhibitors .

HY-78248

4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents
4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-100040R

Ethyl 1H-pyrazole-4-carboxylate (Standard) 4-Ethoxycarbonylpyrazole (Standard)	Biochemical Assay Reagents
Ethyl 1H-pyrazole-4-carboxylate (Standard) is the analytical standard of Ethyl 1H-pyrazole-4-carboxylate (HY-100040). This product is intended for research and analytical applications. 4-Ethoxycarbonylpyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W037619

*Pteridine-2,4(1H,3H)-dione*	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Biochemical Assay Reagents
Pteridine-2,4 (1H,3H)-dione is a pteridine derivative (xanthopterin) and a sulfur-containing pteridine compound (2,4-dimercaptopyrimidine). Pteridine-2,4 (1H,3H)-dione possesses metal-binding ability, and forms closed-shell (ionic) interactions with palladium via sulfur and nitrogen atoms. Pteridine-2,4 (1H,3H)-dione derivates can be used in studies related to neuroblastoma, glioma and breast cancer .

HY-W555382

Pseudane IX 2-Nonylquinolin-4(1H)-one	Alkaloids Ketones, Aldehydes, Acids Ruta graveolens Linn. Rutaceae Quinoline Alkaloids Plants Source Classification	HCV
Pseudane IX, a compound isolated from the leaves of Ruta angustifolia, has strong anti-HCV activity with an IC₅₀ value of 1.4 μg/mL. Pseudane IX reduces HCV RNA replication and viral protein synthesis levels .

HY-W002065

4-Carboxypyrazole	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite Drug Intermediate
4-Carboxypyrazole (1H-Pyrazole-4-carboxylic acid) is a metabolite of Fomepizole (HY-B0876). 4-Carboxypyrazole is involved in the synthesis of ALKBH1 inhibitors. 4-Carboxypyrazole can be used in the research of gastric cancer .

HY-N9530

*1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone*	Cardiovascular Disease Alkaloids Classification of Application Fields Evodia rutaecarpa (Juss.) Benth. Rutaceae Metabolic Disease Quinoline Alkaloids Plants Disease Research Fields Source Classification	Acyltransferase Angiotensin Receptor Bacterial
1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, with IC₅₀s of 20.1 μM and 34.1 μM, respectively. 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows potent anti-Helicobacter pylori activity with the MIC of 10 μg/mL .

HY-N1638

*1-Methyl-2-undecyl-4(1H)-quinolone*	Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Quinoline Alkaloids Plants Source Classification	Monoamine Oxidase
1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC₅₀ and K_i values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS .

HY-N1637

*1-Methyl-2-pentyl-4(1H)-quinolinone*	Infection Alkaloids other families Classification of Application Fields Quinoline Alkaloids Plants Disease Research Fields Source Classification	Bacterial
1-Methyl-2-pentyl-4(1H)-quinolinone, a quinolone alkaloid isolated from the fruits of Evodia Rutaecarpa, possesses antibacterial and cytotoxic activities for cancer cells .

HY-N10456

*1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone*	Natural Products Rutaceae Plants Tetradium ruticarpum (A. Jussieu) T. G. Hartley Source Classification	Bacterial
1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone is a potent antibacterial agent with an MIC₅₀ value of 22 µM and an MIC₉₀ value of 50 µM for Helicobacter pyloriStrain 51. 1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone has the potential for the research of gastric and duodenal ulcers .

HY-N0968

*1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone*	Alkaloids Classification of Application Fields Evodia rutaecarpa (Juss.) Benth. Rutaceae Other Diseases Quinoline Alkaloids Plants Disease Research Fields Source Classification	Others
1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone, as a colorless oil, is a quinolone alkaloid isolated from the fruit of Evodia rutaecarpa BENTHAM (Rutaceae) .

HY-N9520

*1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone*	Cardiovascular Disease Alkaloids Classification of Application Fields Evodia rutaecarpa (Juss.) Benth. Rutaceae Quinoline Alkaloids Plants Disease Research Fields Source Classification	Angiotensin Receptor
Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is an antagonist of angiotensin II receptor (IC₅₀=48.2 μM). Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is a quinolone alkaloid from Evodia rutaecarpa .

HY-N10907

4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-	Alkaloids Rutaceae Plants Tetradium ruticarpum (A. Jussieu) T. G. Hartley Source Classification	Bacterial
4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- (compound 2) is a quinolone alkaloid that can be isolated from Cnidium. 4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- has methicillin-resistant Staphylococcus aureus (MRSA) activity, with MIC values of 32 μg/mL (ATCC 33591) and 16 μM/mL (ATCC 25923), respectively .

HY-402321

*2-Octyl-4(1H)-quinolone*	Alkaloids Other Alkaloids Ruta graveolens Linn. Rutaceae Plants Source Classification	Others
2-Octyl-4(1H)-quinolone (Compound 14) is a quinolinone alkaloid that can be isolated from Ruta graveolens .

HY-N1636

*1-Methyl-2-nonyl-4(1H)-quinolone*	Alkaloids Neurological Disease Classification of Application Fields Rutaceae Quinoline Alkaloids Plants Disease Research Fields Source Classification	Monoamine Oxidase
1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC₅₀ of 12.1 μM .

HY-W037619R

*Pteridine-2,4(1H,3H)-dione (Standard)*	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Pteridine-2,4(1H,3H)-dione is an endogenous metabolite.

HY-N16462

*2-(2-Heptenyl)-3-methyl-4(1H)-quinolone*	Natural Products Microorganisms Source Classification	Bacterial
2-(2-Heptenyl)-3-methyl-4(1H)-quinolone is a quinoline alkaloid found in Burkholderia sp. VY81. 2-(2-Heptenyl)-3-methyl-4(1H)-quinolone is promising for research of bacterial diseases in rice (e.g., soft rot) and other plant pathogens (e.g., Pythium ultimum, Fusarium oxysporum) .

Cat. No.	Product Name	Chemical Structure

HY-W741652

2-(2-Chloroethyl-d4)-1H-isoindole-1,3-dione
2-(2-Chloroethyl-d₄)-1H-isoindole-1,3-dione is the deuterium labeled 2-(2-Chloroethyl)isoindoline-1,3-dione (HY-W014424).

HY-154741S

*6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione-15N2*
6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione- ¹⁵N₂ is ¹⁵N labeled (HY-154741).

HY-W555382S

Pseudane IX-d4
Pseudane IX-d₄ (2-Nonylquinolin-4(1H)-one-d₄) is deuterium labeled Pseudane IX. Pseudane IX, a compound isolated from the leaves of Ruta angustifolia, has strong anti-HCV activity with an IC₅₀ value of 1.4 μg/mL. Pseudane IX reduces HCV RNA replication and viral protein synthesis levels .

HY-W751834

*6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione-13C3*
6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione- ¹³C₃ (NSC 99321- ¹³C₃) is the ¹³C-labeled 6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione (HY-W016913).

HY-W768482

*2-Amino-6-hydroxypyrimidin-4(1H)-one-13C2*
2-Amino-6-hydroxypyrimidin-4(1H)-one- ¹³C₂ (2-Amino-6-hydroxy-1H-pyrimidin-4-one- ¹³C₂) is the ¹³C-labeled 2-Amino-6-hydroxypyrimidin-4(1H)-one (HY-Y0559).

HY-W701580

*6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione-d3*
6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione-d₃ (6-Amino-3-methyluracil-d₃) is the deuterium labeled 6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione (HY-W038777).

HY-W340583S

(2-(1H-indol-3-yl)acetyl)-L-leucine-d4
(2-(1H-indol-3-yl)acetyl)-L-leucine-d₄ is deuterium labeled (2-(1H-indol-3-yl)acetyl)-L-leucine .

HY-W766242

1'-Epi 3,5-Dibenzoate-2,2-difluorouridine-13C,15N2
1'-Epi 3,5-Dibenzoate-2,2-difluorouridine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 1-(3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione (HY-W778177).

HY-W777759

6-Amino-5-nitroso-2-thiouracil-13C,15N
6-Amino-5-nitroso-2-thiouracil- ¹³C, ¹⁵N (4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine- ¹³C, ¹⁵N) is the ¹³C- and ¹⁵N-labeled 6-Amino-5-nitroso-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (HY-75602).

Cat. No.	Product Name		Classification

HY-152877

Isocytidine		Nucleoside Analogs Cytidine
2-Amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154325

*1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone*		Nucleoside Analogs
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152603

*2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone*		Nucleoside Analogs
2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152853

*3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione*		Nucleoside Analogs
3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154663

*1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione*		Nucleoside Analogs
1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154335

*1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione*		Nucleoside Analogs
1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152676

*1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione*		Nucleoside Analogs
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-154652

*1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione*		Nucleoside Analogs
1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-154613

*(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione*		Nucleoside Analogs
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152878

Arabinosylisocytosine NSC 529488		Nucleoside Analogs Cytidine
2-Amino-1-β-D-arabinofuranosyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

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