Antioxidant agent-11
Based on 1 Customer Validation
Antioxidant agent-11 is a 2-pyrazole-2,3-dihydroquinazolin-4(1H)-one derivative and a weak antioxidant. Antioxidant agent-11 scavenges DPPH free radicals. Antioxidant agent-11 can be used for the research of lung carcinoma.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 474379-42-5
- Formula: C23H18N4O
- Molecular Weight:366.42
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Antioxidant agent-11 (Compound 3d) (100 μg/mL; 72 h) inhibits proliferation of human lung carcinoma A549 cells by 54.07%[1].
Antioxidant agent-11 (100-500 μg/mL) exhibits weak DPPH free radical scavenging ability[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human lung carcinoma A549 cell line
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Concentration:100 μg/mL
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Incubation Time:72 h
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Result:Inhibited A549 cell proliferation by 54.07%.
Chemical Information
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CAS No. 474379-42-5
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Appearance Solid
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Molecular Weight 366.42
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Formula C23H18N4O
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Color White to off-white
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SMILES
O=C1NC(C2=CN(C3=CC=CC=C3)N=C2C4=CC=CC=C4)NC5=C1C=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (272.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.7291 mL | 13.6455 mL | 27.2911 mL | 68.2277 mL |
| 5 mM | 0.5458 mL | 2.7291 mL | 5.4582 mL | 13.6455 mL | |
| 10 mM | 0.2729 mL | 1.3646 mL | 2.7291 mL | 6.8228 mL | |
| 15 mM | 0.1819 mL | 0.9097 mL | 1.8194 mL | 4.5485 mL | |
| 20 mM | 0.1365 mL | 0.6823 mL | 1.3646 mL | 3.4114 mL | |
| 25 mM | 0.1092 mL | 0.5458 mL | 1.0916 mL | 2.7291 mL | |
| 30 mM | 0.0910 mL | 0.4549 mL | 0.9097 mL | 2.2743 mL | |
| 40 mM | 0.0682 mL | 0.3411 mL | 0.6823 mL | 1.7057 mL | |
| 50 mM | 0.0546 mL | 0.2729 mL | 0.5458 mL | 1.3646 mL | |
| 60 mM | 0.0455 mL | 0.2274 mL | 0.4549 mL | 1.1371 mL | |
| 80 mM | 0.0341 mL | 0.1706 mL | 0.3411 mL | 0.8528 mL | |
| 100 mM | 0.0273 mL | 0.1365 mL | 0.2729 mL | 0.6823 mL |
Antioxidant agent-11 Related Classifications
HY-153757 Related Classifications
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