1. Neuronal Signaling
  2. Monoamine Oxidase
  3. 1-Methyl-2-undecyl-4(1H)-quinolone

1-Methyl-2-undecyl-4(1H)-quinolone 

Cat. No.: HY-N1638
Handling Instructions

1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS.

For research use only. We do not sell to patients.

1-Methyl-2-undecyl-4(1H)-quinolone Chemical Structure

1-Methyl-2-undecyl-4(1H)-quinolone Chemical Structure

CAS No. : 59443-02-6

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Description

1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS[1][2].

IC50 & Target[2]

MAO-B

15.3 μM (IC50)

MAO-B

9.91 μM (Ki)

In Vitro

1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

313.48

Formula

C₂₁H₃₁NO

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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1-Methyl-2-undecyl-4(1H)-quinolone
Cat. No.:
HY-N1638
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