1. Neuronal Signaling
  2. Monoamine Oxidase
  3. Toloxatone

Toloxatone (Synonyms: MD 69276)

Cat. No.: HY-14196 Purity: 99.34%
Handling Instructions

Toloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor. Antidepressant.

For research use only. We do not sell to patients.

Toloxatone Chemical Structure

Toloxatone Chemical Structure

CAS No. : 29218-27-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
5 mg USD 60 In-stock
Estimated Time of Arrival: December 31
10 mg USD 100 In-stock
Estimated Time of Arrival: December 31
25 mg USD 210 In-stock
Estimated Time of Arrival: December 31
50 mg USD 360 In-stock
Estimated Time of Arrival: December 31
100 mg USD 640 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Toloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor[1]. Antidepressant[1].

IC50 & Target

MAOA[1]

Molecular Weight

207.23

Formula

C₁₁H₁₃NO₃

CAS No.

29218-27-7

SMILES

CC1=CC(N2C(OC(CO)C2)=O)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (603.19 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8256 mL 24.1278 mL 48.2556 mL
5 mM 0.9651 mL 4.8256 mL 9.6511 mL
10 mM 0.4826 mL 2.4128 mL 4.8256 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (10.04 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (10.04 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (10.04 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Toloxatone
Cat. No.:
HY-14196
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