1. Neuronal Signaling
  2. Monoamine Oxidase
  3. Azure B

Azure B (Synonyms: Azure B chloride)

Cat. No.: HY-D0004 Purity: 96.08%
Handling Instructions

Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is used in making Azure eosin stains for blood smear staining. Azure B is a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. Azure B possesses significant antidepressant-like effects.

For research use only. We do not sell to patients.

Azure B Chemical Structure

Azure B Chemical Structure

CAS No. : 531-55-5

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Estimated Time of Arrival: December 31
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Description

Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is used in making Azure eosin stains for blood smear staining. Azure B is a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. Azure B possesses significant antidepressant-like effects[1][2].

In Vivo

Azure B (4-30 mg/kg; i.p.; once) decreases immobility in the forced swim test (FST)[1].

Molecular Weight

305.83

Formula

C₁₅H₁₆ClN₃S

CAS No.

531-55-5

SMILES

CNC1=CC2=[S+]C3=C(C=CC(N(C)C)=C3)N=C2C=C1.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: 96.08%

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Keywords:

Azure BMonoamine OxidaseMAOdyemetaboliteantidepressant-likestainsreversibleInhibitorinhibitorinhibit

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Azure B
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