59443-02-6
Chemical Structure
1-Methyl-2-undecyl-4(1H)-quinolone
- CAS No.: 59443-02-6
- Formula:C21H31NO
- Molecular Weight:313.48
IUPAC Name: 1-methyl-2-undecylquinolin-4(1H)-one
InChIKey: ZLIHBZFNMQLPOT-UHFFFAOYSA-N
SMILES: O=C1C=C(CCCCCCCCCCC)N(C)C2=C1C=CC=C2
Biological Activity: 1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS[1][2].
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1-Methyl-2-undecyl-4(1H)-quinolone | 1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS. | |||||||||||||||||||||
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Keywords
