Search Result
Results for "
Organophosphorus
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-136924
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FAAH
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Others
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FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads .
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- HY-108712
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TDCPP
Maximum Cited Publications
8 Publications Verification
Tris(1,3-dichloroisopropyl)phosphate
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Biochemical Assay Reagents
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Cancer
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TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment.
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- HY-B1200
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2-PAM chloride
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Cholinesterase (ChE)
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Neurological Disease
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Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
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- HY-W016188
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Cholinesterase (ChE)
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Others
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1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .
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- HY-101417
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Diethyl phosphoric acid
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Endogenous Metabolite
Interleukin Related
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Others
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Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
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- HY-B1881
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- HY-B1885
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Environmental Pollutants
Apoptosis
Insecticide
Cholinesterase (ChE)
AMPK
PI3K
Parasite
Akt
SOD
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Infection
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Fenitrothion is a broad-spectrum and orally active insecticide/acaricide. Fenitrothion inhibits cholinesterase, AMPKα and IRS1/PI3K/AKT. Fenitrothion causes Apoptosis, reduces SOD activity. Fenitrothion shows insecticidal effect against Rhyzopertha dominica and Tribolium castaneum adults. Fenitrothion is widely used in cotton crops, vegetable crops, fruit crops and field crops, especially rice. Fenitrothion can be used for brain and spleen toxicology studies .
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- HY-B2053
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Fungal
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Infection
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Tolclofos-methyl is an organophosphorus fungicide. Tolclofos-methyl undergoes photoinduced oxidative degradation to form oxo-analog derivatives. Tolclofos-methyl inhibits spore division in fungi and oomycetes, induces cytoplasmic leakage, and interferes with flagellar movement. Tolclofos-methyl is rapidly metabolized and excreted in rodents. Tolclofos-methyl can be used in studies related to fungal infections .
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- HY-W008954
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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Tris(2-ethylhexyl) phosphate is an organophosphorus flame retardant analog with considerable ecological toxicity. Tris(2-ethylhexyl) phosphate can be used as neutral carriers to make organic ammonium ion-selective membrane electrodes. Tris(2-ethylhexyl) phosphate is widely applied in furniture, textiles, building materials, electronics, and other chemicals .
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- HY-B1863
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Environmental Pollutants
Cholinesterase (ChE)
Fungal
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Infection
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Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos can phosphorylate the -OH group on the serine residue in the active (esteratic) site of ChEs and so inhibit both AChE and BChE activity .
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- HY-101417S1
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Diethyl phosphoric acid-d10
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Endogenous Metabolite
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Others
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Diethyl phosphate-d10-1 is the deuterium labeled Diethyl phosphate. Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
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- HY-118165
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- HY-121185
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Adrenergic Receptor
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Infection
Neurological Disease
Inflammation/Immunology
Endocrinology
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Hexoprenaline is an orally active and selective β-adrenergic receptor agonist. Hexoprenaline can dilate the bronchi. Hexoprenaline can activate adenylate cyclase and increases 14C-Aminopyrine uptake. Hexoprenaline exhibits anti-infection and anti-inflammmation effect. Hexoprenaline can increase placental weight and blood flow. Hexoprenaline can be used for the researches of inflammation, immunology, infection, endocrinology and neurological disease, such as asthma, chronic bronchitis, sepsis and intoxication of organophosphorus compounds .
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- HY-126199
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Endogenous Metabolite
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Others
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Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .
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- HY-W016188R
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Reference Standards
Cholinesterase (ChE)
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Others
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1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .
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- HY-108712R
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Tris(1,3-dichloroisopropyl)phosphate (Standard)
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Biochemical Assay Reagents
Reference Standards
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Cancer
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TDCPP (Standard) is the analytical standard of TDCPP. This product is intended for research and analytical applications. TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment.
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- HY-101417R
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Diethyl phosphoric acid (Standard)
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Reference Standards
Endogenous Metabolite
Interleukin Related
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Others
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Diethyl phosphate (Standard) is the analytical standard of Diethyl phosphate. This product is intended for research and analytical applications. Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
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- HY-I0607A
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Biochemical Assay Reagents
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Others
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(1-Ethoxy-1-oxopropan-2-yl)triphenylphosphonium bromide is an important raw material and intermediate in organic synthesis, pharmaceuticals, agrochemicals, and dyes. (1-Ethoxy-1-oxopropan-2-yl)triphenylphosphonium bromide is widely used as an organophosphorus catalyst .
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- HY-129925
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Insecticide
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Others
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CP-49674 is an organophosphorus compound. CP-49674 can be used as an insecticide to control the common cattle grub .
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- HY-119438
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Insecticide
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Others
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Aspon is an organophosphorus insecticide. Aspon can be utilized as phosphorus sources by bacteria .
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- HY-169366
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- HY-B2016
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Herbicide
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Others
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Anilofos is a pre-emergence, organophosphorus herbicide. Anilofos has moderate toxic potential in mammals .
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- HY-W587529
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Drug Intermediate
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Others
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2-Chloroethyl (2-chloroethyl)phosphonate is an Organophosphorus compound and can be used as an intermediate in organic synthesis.
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- HY-B1738
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Cholinesterase (ChE)
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Neurological Disease
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Pralidoxime is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime is an antidote for organophosphate poisoning .
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- HY-157359
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Biochemical Assay Reagents
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Others
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Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .
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- HY-P3183
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Diisopropylfluorophosphatase
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Biochemical Assay Reagents
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Others
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Organophosphorus acid anhydrolase (Diisopropylfluorophosphatase) is a hydrolase that target phosphoanhydride bonds of organophosphate compounds such as phosphorus-halide and phosphoruscyanide .
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- HY-118165R
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Reference Standards
Cholinesterase (ChE)
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Neurological Disease
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Phenthoate (Standard) is the analytical standard of Phenthoate. This product is intended for research and analytical applications. Phenthoate is an organophosphorus pesticide having low toxicity in animals. Phenthoate is also a AChE inhibitor .
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- HY-W783157
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Heterofos
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Insecticide
Cholinesterase (ChE)
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Infection
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Heterophos (Heterofos) is an organophosphorus insecticide and an AChE inhibitor. Heterophos inhibits AChE's function of decomposing acetylcholine, causing disorder of insect nerve conduction and exerting insecticidal effects .
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- HY-B1881R
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Reference Standards
Insecticide
Cholinesterase (ChE)
Parasite
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Infection
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Pirimiphos-methyl (Standard) is the analytical standard of Pirimiphos-methyl (HY-B1881). This product is intended for research and analytical applications. Pirimiphos-methyl is an organophosphorus insecticide and acaricide that can inhibit AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains.
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- HY-B1863R
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Reference Standards
Fungal
Cholinesterase (ChE)
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Infection
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Iprobenfos (Standard) is the analytical standard of Iprobenfos (HY-B1863). This product is intended for research and analytical applications. Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos can phosphorylate the -OH group on the serine residue in the active (esteratic) site of ChEs and so inhibit both AChE and BChE activity .
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- HY-119525
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Insecticide
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Infection
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Propetamphos is an organophosphorus insecticide. Propetamphos causes cytotoxicity and oxidative stress .
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- HY-118853
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Insecticide
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Others
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Dichlofenthion is an organophosphorus (OP) pesticide. Dichlofenthion can be for the control of sheep maggot fly .
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- HY-116870
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Parasite
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Infection
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Vamidothion is a polar organophosphorus insecticide and acaricide with biological activity against insects and mites. Vamidothion is degraded by human serum albumin (HSA) and promotes adduct formation with tyrosine residues. The phosphate amino acid adducts formed after the reaction of vamidothion with HSA are detected by liquid chromatography quadrupole-Orbitrap mass spectrometry. The metabolites of vamidothion can be used in forensic toxicology to help determine deaths caused by organophosphorus poisoning .
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- HY-129468
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Cholinesterase (ChE)
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Neurological Disease
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Pirimiphos ethyl is a kind of organophosphorus pesticide that commonly employes for the protection of crops including vegetables, bananas, turf and mushrooms through the inhibition of acetylcholinesterase activity .
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- HY-123120
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Thrombin
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Others
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SA-152 is an organophosphorus inhibitor. SA-152 modulates the fibrinogen coagulation and TAME esterase activity of bovine α-thrombin .
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- HY-148909
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IDEFP
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Cannabinoid Receptor
FAAH
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Neurological Disease
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Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester that antagonizes the central cannabinoid receptor (CB1) and inhibits FAAH with similar potencies (IC50 = 2 nM) .
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- HY-118165S
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- HY-B2016R
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Herbicide
Reference Standards
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Others
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Anilofos (Standard) is the analytical standard of Anilofos. This product is intended for research and analytical applications. Anilofos is a pre-emergence, organophosphorus herbicide. Anilofos has moderate toxic potential in mammals .
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- HY-116857R
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Reference Standards
Fungal
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Others
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Ditalimfos (Standard) is the analytical standard of Ditalimfos. This product is intended for research and analytical applications. Ditalimfos is an organophosphate fungicide. Ditalimfos is mainly used in agriculture to control fungal diseases of crops. Ditalimfos can be used for fungal resistance studies and risk assessment of residues in the environment .
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- HY-116857
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Fungal
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Others
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Ditalimfos is an organophosphate fungicide. Ditalimfos is mainly used in agriculture to control fungal diseases of crops. Ditalimfos can be used for fungal resistance studies and risk assessment of residues in the environment .
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- HY-156399
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- HY-126199R
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Endogenous Metabolite
Reference Standards
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Others
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Tetrachlorvinphos (Standard) is the analytical standard of Tetrachlorvinphos. This product is intended for research and analytical applications. Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .
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- HY-126199S
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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(Z)-Tetrachlorvinphos-d6 is the deuterium labeled Tetrachlorvinphos (HY-126199). Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .
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- HY-129468R
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Reference Standards
Cholinesterase (ChE)
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Neurological Disease
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Pirimiphos ethyl (Standard) is the analytical standard of Pirimiphos ethyl. This product is intended for research and analytical applications. Pirimiphos ethyl is a kind of organophosphorus pesticide that commonly employes for the protection of crops including vegetables, bananas, turf and mushrooms through the inhibition of acetylcholinesterase activity .
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- HY-B1885R
-
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Reference Standards
Insecticide
Parasite
Cholinesterase (ChE)
AMPK
PI3K
Akt
Apoptosis
SOD
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Infection
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Fenitrothion (Standard) is the analytical standard of Fenitrothion (HY-B1885). This product is intended for research and analytical applications. Fenitrothion is a broad-spectrum and orally active insecticide/acaricide. Fenitrothion inhibits cholinesterase, AMPKα and IRS1/PI3K/AKT. Fenitrothion causes Apoptosis, reduces SOD activity. Fenitrothion shows insecticidal effect against Rhyzopertha dominica and Tribolium castaneum adults. Fenitrothion is widely used in cotton crops, vegetable crops, fruit crops and field crops, especially rice. Fenitrothion can be used for brain and spleen toxicology studies .
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- HY-B1881S
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Isotope-Labeled Compounds
Insecticide
Cholinesterase (ChE)
Parasite
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Infection
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Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl (HY-B1881) . Pirimiphos-methyl is an organophosphorus insecticide and acaricide that can inhibit AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains .
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- HY-B1200R
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2-PAM chloride (Standard)
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Reference Standards
Cholinesterase (ChE)
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Neurological Disease
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Pralidoxime (chloride) (Standard) is the analytical standard of Pralidoxime (chloride). This product is intended for research and analytical applications. Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
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- HY-B2053R
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Reference Standards
Bacterial
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Infection
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Tolclofos-methyl (Standard) is the analytical standard of Tolclofos-methyl (HY-B2053). This product is intended for research and analytical applications. Tolclofos-methyl is an organophosphorus fungicide. Tolclofos-methyl undergoes photoinduced oxidative degradation to form oxo-analog derivatives. Tolclofos-methyl inhibits spore division in fungi and oomycetes, induces cytoplasmic leakage, and interferes with flagellar movement. Tolclofos-methyl is rapidly metabolized and excreted in rodents. Tolclofos-methyl can be used in studies related to fungal infections .
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- HY-121185A
-
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Adrenergic Receptor
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Infection
Neurological Disease
Inflammation/Immunology
Endocrinology
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Hexoprenaline sulfate is an orally active and selective β-adrenergic receptor agonist. Hexoprenaline sulfate can dilate the bronchi. Hexoprenaline sulfate can activate adenylate cyclase and increases 14C-Aminopyrine uptake. Hexoprenaline sulfate exhibits anti-infection and anti-inflammmation effect. Hexoprenaline sulfate can increase placental weight and blood flow. Hexoprenaline sulfate can be used for the researches of inflammation, immunology, infection, endocrinology and neurological disease, such as asthma, chronic bronchitis, sepsis and intoxication of organophosphorus compounds .
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- HY-W741033
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Drug Metabolite
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Others
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Demeton-S sulfone is an oxidative metabolite of the organophosphorus insecticide Disulfoton .
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- HY-400849
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Drug Intermediate
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Others
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Losartan impurity 14 (Compound I) is a Losartan (HY-17512) impurity containing an azido group. Losartan impurity 14 can be converted into an amino compound via organophosphorus reagents .
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- HY-133992
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Drug Metabolite
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Others
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Fensulfothion sulfone is a metabolite of the organophosphorus insecticide fensulfothion.
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- HY-107852
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Insecticide
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Others
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Demeton-S-methyl sulfone is an organophosphorus insecticide metabolite.Demeton-S-methyl sulfone serves as a substrate for metabolic breakdown.Demeton-S-methyl sulfone forms via oxidation of demeton S-methyl sulfoxide in sugar-beet cell suspension cultures.Demeton-S-methyl sulfone undergoes thioester bond cleavage, producing ethanethiols that convert into S-methylated compounds or S-glucosides .
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- HY-W338799
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- HY-183750
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Cholinesterase (ChE)
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Metabolic Disease
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BChE reactivator-1 is a human butyrylcholinesterase (BChE) activator and antidote, with a Ki value of 0.52 μM against human BChE. BChE reactivator-1 activates BChE inhibited by organophosphorus compounds, binds reversibly to native BChE, and restores cholinesterase activity in human whole blood. BChE reactivator-1 is applicable to research related to organophosphorus poisoning .
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- HY-W701712
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Drug Derivative
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Others
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Fenamiphos sulfone is the oxidative metabolite of the organophosphorus pesticide fenamiphos. Fenamiphos sulfone undergoes biotransformation and accumulates in aquatic and terrestrial algal species .
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- HY-119525R
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Insecticide
Reference Standards
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Infection
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Propetamphos (Standard) is the analytical standard of Propetamphos. This product is intended for research and analytical applications. Propetamphos is an organophosphorus insecticide. Propetamphos causes cytotoxicity and oxidative stress .
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- HY-134099
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Drug Metabolite
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Others
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Vamidothion-sulfone is the oxidative metabolite of the insecticide and acaricide Vamidothion (HY-116870) .
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- HY-N7617R
-
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Reference Standards
Keap1-Nrf2
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Cancer
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Pirimiphos ethyl (Standard) is the analytical standard of Pirimiphos ethyl. This product is intended for research and analytical applications. Pirimiphos ethyl is a kind of organophosphorus pesticide that commonly employes for the protection of crops including vegetables, bananas, turf and mushrooms through the inhibition of acetylcholinesterase activity .
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- HY-B1738B
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Cholinesterase (ChE)
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Neurological Disease
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Pralidoxime methanesulfonate is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime methanesulfonate reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime methanesulfonate is an antidote for organophosphate poisoning .
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- HY-120131
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Insecticide
Cholinesterase (ChE)
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Neurological Disease
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Cyanofenphos is an orally active organophosphate insecticide and brain AChE inhibitor with neurotoxicity. Cyanofenphos induces delayed neurotoxicity such as ataxia and paralysis. Cyanofenphos also causes symptoms including somnolence, reduced feed intake and weight loss in hens. Cyanofenphos has a unique self-antagonistic effect: repeated low-dose pre-treatment not only reduces subsequent acute toxicity, but also exacerbates delayed neurotoxicity and attenuates enzyme inhibition, with the protective effect peaking at 24 h after the last pre-treatment. Cyanofenphos is commonly used in studies related to delayed neurotoxicity .
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- HY-181136
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Estrogen Receptor/ERR
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Metabolic Disease
Cancer
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Antiestrogenic agent-1, an organophosphorus 13α-estrone derivative, is an antiestrogenic agent. Antiestrogenic agent-1 can disrupt estrogen signaling by inhibiting estrogen-mediated transcriptional activity. Antiestrogenic agent-1 can inhibit cancer cells proliferation, migration, invasion and induce G1-phase arrest. Antiestrogenic agent-1 mitigates estrogen-induced uterine growth in immature rats and inhibits tumor growth in a murine triple-negative breast cancer mice model. Antiestrogenic agent-1 can be used for the researches of cancer and endocrinology,such as breast cancer, oropharyngeal squamous cell carcinoma .
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- HY-W275793
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Glycerol tripropionate
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Carboxylesterase (CES)
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Others
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Tripropionin (Glycerol tripropionate) is a triglyceride that can be hydrolyzed by carboxylic esterase from carrots. Tripropionin can serve as the oil phase for constructing high-performance lipid nanoemulsion droplets, enabling efficient encapsulation of Combretastatin A4 (HY-N2146) to achieve its stable storage and controlled release .
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| Cat. No. |
Product Name |
Type |
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- HY-I0607A
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Biochemical Assay Reagents
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(1-Ethoxy-1-oxopropan-2-yl)triphenylphosphonium bromide is an important raw material and intermediate in organic synthesis, pharmaceuticals, agrochemicals, and dyes. (1-Ethoxy-1-oxopropan-2-yl)triphenylphosphonium bromide is widely used as an organophosphorus catalyst .
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- HY-157359
-
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Biochemical Assay Reagents
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Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
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- HY-101417S1
-
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Diethyl phosphate-d10-1 is the deuterium labeled Diethyl phosphate. Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
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- HY-118165S
-
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Phenthoate-d6 is deuterium labeled Phenthoate. Phenthoate is an organophosphorus pesticide having low toxicity in animals. Phenthoate is also a AChE inhibitor .
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- HY-126199S
-
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(Z)-Tetrachlorvinphos-d6 is the deuterium labeled Tetrachlorvinphos (HY-126199). Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .
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- HY-B1881S
-
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Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl (HY-B1881) . Pirimiphos-methyl is an organophosphorus insecticide and acaricide that can inhibit AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains .
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