2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. KR-27425

AChE activator 1 (compound 13) is a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase(AChE).

For research use only. We do not sell to patients.

KR-27425

KR-27425 Chemical Structure

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Description

AChE activator 1 (compound 13) is a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase(AChE)[1].

Cellular Effect
Cell Line Type Value Description References
CHO-K1 CC50
> 100 μM
Compound: 13; KR-27425
Cytotoxicity against CHO-K1 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against CHO-K1 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
[PMID: 37838342]
HFL1 CC50
> 100 μM
Compound: 13; KR-27425
Cytotoxicity against human HFL1 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human HFL1 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
[PMID: 37838342]
L929 CC50
> 100 μM
Compound: 13; KR-27425
Cytotoxicity against mouse L929 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against mouse L929 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
[PMID: 37838342]
NIH3T3 CC50
> 100 μM
Compound: 13; KR-27425
Cytotoxicity against mouse NIH3T3 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against mouse NIH3T3 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
[PMID: 37838342]
Vero CC50
> 100 μM
Compound: 13; KR-27425
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
[PMID: 37838342]
Molecular Weight

215.29

Formula

C10H21N3O2
SMILES

CC(CCCNCCNC(/C=N/O)=O)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KR-27425 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KR-27425KR27425KR 27425Endogenous MetaboliteAcetylcholinesteraseOrganophosphorus agentsOximeReactivatorInhibitorinhibitorinhibit

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KR-27425
Cat. No.:
HY-156399
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