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Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .
Ranibizumab (RG-6321) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110, VEGF121, and VEGF165) . Ranibizumab slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research .
Ranibizumab (RG-6321) (anti-VEGF) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110, VEGF121, and VEGF165) . Ranibizumab (anti-VEGF) slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research .
ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1, used in the research of angiogenesis . ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes .
Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial .
Mizolastine dihydrochloride is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine dihydrochloride effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine dihydrochloride can be used in studies of allergic rhinitis and chronic idiopathic urticarial .
Ranibizumab (RG-6321) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110, VEGF121, and VEGF165) . Ranibizumab slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research .
Ranibizumab (RG-6321) (anti-VEGF) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110, VEGF121, and VEGF165) . Ranibizumab (anti-VEGF) slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research .
VEGF145 Protein, with limited expression, exhibits specialized distribution and is not broadly present in tissues. Its restricted occurrence implies a specific, context-dependent role in physiological processes. Further research is needed to unveil the specific cellular contexts and functions where VEGF145 actively participates, providing insights into its potential contributions to localized biological activities. VEGF165 Protein, Human (HEK293, C-His) is the recombinant human-derived VEGF165 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of VEGF165 Protein, Human (HEK293, C-His) is 165 a.a., with molecular weight of 20-23 kDa.
VEGF165 Protein, Human (P.pastoris) is a Vascular Endothelial Growth Factor A (VEGF-A) isoform. VEGF is a heparin-binding growth factor specific for vascular endothelial cells that is able to induce angiogenesis.
VEGF165 Protein, Human (HEK293) is a Vascular Endothelial Growth Factor A (VEGF-A) isoform. VEGF is a heparin-binding growth factor specific for vascular endothelial cells that is able to induce angiogenesis.
The VEGF165 protein is an important growth factor that actively drives vasculogenesis, vasculogenesis, and endothelial cell growth. Its multiple effects include inducing endothelial cell proliferation, promoting migration, inhibiting apoptosis, and increasing vascular permeability. VEGF165 Protein, zebrafish (sf9) is the recombinant VEGF165 protein, expressed by Sf9 insect cells , with tag free. The total length of VEGF165 Protein, zebrafish (sf9) is 188 a.a., with molecular weight of ~22 kDa.
VEGF165 is a member of the PDGF/VEGF family encoding a heparin-binding homodimer that is crucial in inducing vascular endothelial cell proliferation and migration during angiogenesis. The VEGF gene is critical for blood vessel development, and its disruption leads to abnormal blood vessel formation in mouse embryos. VEGF165 Protein, Human (Biotinylated, HEK293, Avi) is the recombinant human-derived VEGF165 protein, expressed by HEK293 , with N-Avi labeled tag. The total length of VEGF165 Protein, Human (Biotinylated, HEK293, Avi) is 165 a.a., with molecular weight of 25-30 kDa.
VEGF145 Protein, with limited expression, exhibits specialized distribution and is not broadly present in tissues. Its restricted occurrence implies a specific, context-dependent role in physiological processes. Further research is needed to unveil the specific cellular contexts and functions where VEGF145 actively participates, providing insights into its potential contributions to localized biological activities. VEGF165 Protein, Human (HEK293, His-Avi) is the recombinant human-derived VEGF165 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of VEGF165 Protein, Human (HEK293, His-Avi) is 165 a.a., with molecular weight of 28-32 kDa.
VEGF145 Protein, with limited expression, exhibits specialized distribution and is not broadly present in tissues. Its restricted occurrence implies a specific, context-dependent role in physiological processes. Further research is needed to unveil the specific cellular contexts and functions where VEGF145 actively participates, providing insights into its potential contributions to localized biological activities. VEGF165 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived VEGF165 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of VEGF165 Protein, Human (Biotinylated, HEK293, His-Avi) is 165 a.a., with molecular weight of 28-32 kDa.
Neuropilin-2 Protein, a pivotal player, serves as a high-affinity receptor for semaphorins 3C and 3F, VEGF-165, VEGF-145, and PLGF-2. Beyond its role in growth factors, Neuropilin-2 plays a critical function in microbial infection, acting as a receptor facilitating pentamer-dependent entry of human cytomegalovirus into epithelial and endothelial cells. Neuropilin-2 Protein, Human (HEK293, Fc) is the recombinant human-derived Neuropilin-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Neuropilin-2 Protein, Human (HEK293, Fc) is 833 a.a., with molecular weight of 119-129 kDa.
Neuropilin-1 protein plays an important role by binding to VEGF-165, possibly inhibiting its cellular binding and inducing apoptosis. This dual function suggests its role in regulating VEGF-mediated processes. Neuropilin-1 Protein, Human (HEK293, Fc) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Neuropilin-1 Protein, Human (HEK293, Fc) is 623 a.a., with molecular weight of 116-130 kDa.
Neuropilin-2 Protein, a pivotal player, serves as a high-affinity receptor for semaphorins 3C and 3F, VEGF-165, VEGF-145, and PLGF-2. Beyond its role in growth factors, Neuropilin-2 plays a critical function in microbial infection, acting as a receptor facilitating pentamer-dependent entry of human cytomegalovirus into epithelial and endothelial cells. Neuropilin-2 Protein, Human (855a.a, HEK293, His) is the recombinant human-derived Neuropilin-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Neuropilin-2 Protein, Human (855a.a, HEK293, His) is 837 a.a., with molecular weight of 100-110 kDa.
Neuropilin-2 protein, a high affinity receptor, binds to semaphorins 3C and 3F, VEGF-165, VEGF-145, and PLGF-2. It forms a heterodimer with NRP1 and also interacts with PLXNB1, similar to NRP1. Neuropilin-2 Protein, Mouse (864a.a, HEK293, His) is the recombinant mouse-derived Neuropilin-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Neuropilin-2 Protein, Mouse (864a.a, HEK293, His) is 864 a.a., with molecular weight of ~96.5 kDa.
Neuropilin-1 protein plays an important role by binding to VEGF-165, possibly inhibiting its cellular binding and inducing apoptosis. This dual function suggests its role in regulating VEGF-mediated processes. Neuropilin-1 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of Neuropilin-1 Protein, Human (Biotinylated, HEK293, Avi-His) is 623 a.a., with molecular weight of 85-100 kDa.
Neuropilin-1 protein is an important receptor critical for cardiovascular system development, angiogenesis, neuronal circuit formation, and non-nervous system organogenesis. It mediates the chemical pulse activity of signaling proteins, recognizes C-terminal regular motifs on ligands, and promotes cellular internalization and vascular leakage. Neuropilin-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Neuropilin-1 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of Neuropilin-1 Protein, Mouse (HEK293, Fc) is 856 a.a., with molecular weight of ~120 kDa.
Neuropilin-1 protein plays an important role by binding to VEGF-165, possibly inhibiting its cellular binding and inducing apoptosis. This dual function suggests its role in regulating VEGF-mediated processes. Neuropilin-1 Protein, Human (HEK293, His) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Neuropilin-1 Protein, Human (HEK293, His) is 623 a.a., with molecular weight of 85-100 kDa.
Neuropilin-1 protein is an important receptor critical for cardiovascular system development, angiogenesis, neuronal circuit formation, and non-nervous system organogenesis. It mediates the chemical pulse activity of signaling proteins, recognizes C-terminal regular motifs on ligands, and promotes cellular internalization and vascular leakage. Neuropilin-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Neuropilin-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Neuropilin-1 Protein, Mouse (HEK293, His) is 835 a.a., with molecular weight of 100-120 kDa.
Neuropilin-1 Protein plays a significant role by binding to VEGF-165, potentially inhibiting its cellular binding and inducing apoptosis. This dual functionality suggests its role in regulating VEGF-mediated processes. Interactions with semaphorin family members highlight its versatile ligand-binding capability. Neuropilin-1's expression adversely affects blood vessel number and integrity, suggesting a potential role in angiogenesis. Its diverse interactions underscore its importance in orchestrating complex cellular processes and implications in angiogenesis and apoptotic pathways. Neuropilin-1 Protein, Human (Biotinylated, HEK293, His-Avi, solution) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag and V179A mutation. The total length of Neuropilin-1 Protein, Human (Biotinylated, HEK293, His-Avi, solution) is 623 a.a., with molecular weight of ~73.1 kDa.
Neuropilin-1 Protein plays a significant role by binding to VEGF-165, potentially inhibiting its cellular binding and inducing apoptosis. This dual functionality suggests its role in regulating VEGF-mediated processes. Interactions with semaphorin family members highlight its versatile ligand-binding capability. Neuropilin-1's expression adversely affects blood vessel number and integrity, suggesting a potential role in angiogenesis. Its diverse interactions underscore its importance in orchestrating complex cellular processes and implications in angiogenesis and apoptotic pathways. Neuropilin-1 Protein, Human (V179A, HEK293, Fc) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-hFc labeled tag and V179A mutation. The total length of Neuropilin-1 Protein, Human (V179A, HEK293, Fc) is 623 a.a., with molecular weight of ~107.4 kDa.
Neuropilin-1 (NRP1) is one of two neuropilins which acts as a cell-surface receptor which is involved in the development of the cardiovascular system, angiogenesis, the formation of certain neuronal circuits, organogenesis outside the nervous system, cellular internalization and vascular leakage as well as mediates the chemorepulsant activity of semaphorins. NRP1 also binds many ligands and various types of co-receptors to affect cell survival, migration, and attraction. Neuropilin-1 Protein, Human (644a.a, HEK293, His) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-His, C-6*His labeled tag. The total length of Neuropilin-1 Protein, Human (644a.a, HEK293, His) is 623 a.a., with molecular weight of ~90 kDa.
Neuropilin-1 Protein plays a significant role by binding to VEGF-165, potentially inhibiting its cellular binding and inducing apoptosis. This dual functionality suggests its role in regulating VEGF-mediated processes. Interactions with semaphorin family members highlight its versatile ligand-binding capability. Neuropilin-1's expression adversely affects blood vessel number and integrity, suggesting a potential role in angiogenesis. Its diverse interactions underscore its importance in orchestrating complex cellular processes and implications in angiogenesis and apoptotic pathways. Neuropilin-1 Protein, Human (644a.a, HEK293, C-His) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of Neuropilin-1 Protein, Human (644a.a, HEK293, C-His) is 644 a.a., with molecular weight of ~90 kDa.
Neuropilin-1 Protein, a transmembrane glycoprotein, regulates axon guidance, angiogenesis, neuronal development, and immune responses. Neuropilin-1 can interacts with VEGF and semaphorins, and promote the growth, survival, and self-renewal of tumors. Neuropilin-1 also acts as an entry factor and potentiate SARS-CoV-2 and Epstein-Barr virus (EBV) infectivity. Furthermore, Neuropilin-1 acts as a co-receptor for TGF-β, and enhances TGF-β activity via the SMAD2/3 signaling pathway. Neuropilin-1 Protein, Cynomolgus (592a.a, HEK293, His) is the recombinant cynomolgus-derived Neuropilin-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Neuropilin-1 Protein, Cynomolgus (592a.a, HEK293, His) is 592 a.a., with molecular weight of 80-100 kDa.
Neuropilin-1 protein plays an important role by binding to VEGF-165, possibly inhibiting its cellular binding and inducing apoptosis. This dual function suggests its role in regulating VEGF-mediated processes. Neuropilin-1 Protein, Human (619a.a, HEK293, C-His) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Neuropilin-1 Protein, Human (619a.a, HEK293, C-His) is 623 a.a., with molecular weight of approximately 86.92 kDa.
VEGF145 Protein, with limited expression, exhibits specialized distribution and is not broadly present in tissues. Its restricted occurrence implies a specific, context-dependent role in physiological processes. Further research is needed to unveil the specific cellular contexts and functions where VEGF145 actively participates, providing insights into its potential contributions to localized biological activities. Animal-Free VEGF165 Protein, Human (His) is the recombinant human-derived animal-FreeVEGF165 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free VEGF165 Protein, Human (His) is 165 a.a., with molecular weight of ~20.11 kDa.
VEGF145 Protein, with limited expression, exhibits specialized distribution and is not broadly present in tissues. Its restricted occurrence implies a specific, context-dependent role in physiological processes. Further research is needed to unveil the specific cellular contexts and functions where VEGF145 actively participates, providing insights into its potential contributions to localized biological activities. FITC-Labeled VEGF165 Protein, Human (HEK293, C-His) is the recombinant human-derived FITC-Labeled VEGF165 protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of FITC-Labeled VEGF165 Protein, Human (HEK293, C-His) is 165 a.a., with molecular weight of 27-33 kDa.
