33 Results for "

anti-obesity agent

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "anti-obesity agent" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N4103
CAS No.: 17605-67-3
Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research .
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3
3 Cited Publications
Cat. No.: HY-N0547
CAS No.: 1063-77-0
Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent .
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1
1 Cited Publications
Cat. No.: HY-14471
CAS No.: 282526-98-1
Purity:  ≥98.0%
Synonyms: ATL-962
Target:  

Lipase

Research Areas:  

Metabolic Disease

Cetilistat (ATL-962), an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively .
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Cat. No.: HY-14472
CAS No.: 195875-84-4
Purity:  99.31%
Synonyms: NS-2330
Tesofensine (NS-2330) is a triple monoamine reuptake inhibitor inducing a potent inhibition of the re-uptake process in the synaptic cleft of the neurotransmitters dopamine (DA; IC50=6.5 nM), norepinephrine (NE;IC50=1.7 nM), and serotonin (5-HT;IC50=11 nM), and with potentials as an anti-obesity agent . Tesofensine is a CNS acting anti-obesity agent .
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Cat. No.: HY-145605
CAS No.: 1800188-47-9
Purity:  99.74%
Synonyms: HSG4112
Vutiglabridin (HSG4112), a racemic compound, is a potent anti-obesity agent . Vutiglabridin, an optimized structural analog of Glabridin, markedly supersedes Glabridin in weight reduction efficacy and chemical stability .
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Cat. No.: HY-126956
CAS No.: 70579-26-9
Porphyra 334 is a carnosine-like amino acid and a natural photoprotective agent and antioxidant. Porphyra-334 exerts its photoprotective effects by scavenging ROS, inhibiting the expression and activity of MMP-1/8, and promoting the synthesis of collagen and elastin. Porphyra 334 effectively inhibits linoleic acid oxidation induced by alkyl radicals (AAPH) and singlet oxygen. Porphyra 334 has anti-obesity potential by inhibiting the expression of PPARγ2 and C/EBPα. Porphyra 334 protects cells against UV-induced DNA damage and apoptosis by inhibiting the activation of caspase-3 .
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Cat. No.: HY-N7347
CAS No.: 27750-13-6
Synonyms: Garcinia lactone
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis .
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Cat. No.: HY-103249
CAS No.: 303957-69-9
Purity:  98.08%
Synonyms: Reutericycline
Reutericyclin (Reutericycline) is an orally active antibacterial and anti-obesity agent that selectively inhibits Gram-positive bacteria. By selectively dissipating transmembrane potential, Reutericyclin exerts non-lytic bactericidal or bacteriostatic activity against pathogens such as Clostridium difficile and Staphylococcus aureus, and rapidly kills vegetative cells and spores of Clostridium difficile. Reutericyclin possesses favorable properties including resistance to enzymatic hydrolysis, iron-chelating function, and poor absorption by colonic epithelium. Reutericyclin not only eradicates staphylococcal biofilms and inhibits drug-resistant strains, but also counteracts Risperidone (HY-11018)-induced weight gain by inducing changes in gut microbiota composition and restoring energy utilization efficiency. Reutericyclin can be used in research related to Clostridium difficile infection, Risperidone-induced weight gain, and staphylococcal superficial skin infections .
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Cat. No.: HY-161305
CAS No.: 2243575-79-1
Target:  

HDAC

Research Areas:  

Metabolic Disease Cancer

SE-7552, a 2-(difluoromethyl)-1,3,4-oxadiazole (DFMO) derivative, is an orally active, highly selective, non-hydroxamate HDAC6 inhibitor with an IC50 of 33 nM. SE-7552 is greater than 850-fold selectivity versus all other known HDAC isozymes. SE-7552 is capable of blocking multiple myeloma growth in vivo. SE-7552 acts as an anti-obesity agent in diet-induced obese mice .
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Cat. No.: HY-N14035
CAS No.: 90045-23-1
Garcinia cambogia extract is an orally active anti-obesity agent . Garcinia cambogia extract upregulates the gene expression of aP2, SREBP1c, PPARγ2 and C/EBPα. Garcinia cambogia extract reduces the rate of body weight gain, visceral fat accumulation, lipid levels in blood and liver, as well as plasma insulin and leptin levels . Garcinia cambogia extract ameliorates high-fat diet-induced obesity .
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Cat. No.: HY-168467
Target:  

PPAR GLUT

Research Areas:  

Metabolic Disease

Anti-obesity agent 1 (compound 4) shows potential for enhancing lipolysis, exhibiting their anti-obesity properties .
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Cat. No.: HY-P10380
palm11-PrRP31 is a lipidized endogenous appetite inhibitory neuropeptide (PrRP) analogue. palm11-PrRP31 is GPR10 (EC50=39 pM) and NPFF-R2 effective dual agonists. palm11-PrRP31 is able to mimic the natural function of PrRP by binding to these receptors to reduce food intake. palm11-PrRP31 can be used as a potential anti-obesity agent and for the study of neuropeptide-receptor interaction .
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Cat. No.: HY-14472R
CAS No.: 195875-84-4
Synonyms: NS-2330 (Standard)
Tesofensine (Standard) is the analytical standard of Tesofensine. This product is intended for research and analytical applications. Tesofensine (NS-2330) is a triple monoamine reuptake inhibitor inducing a potent inhibition of the re-uptake process in the synaptic cleft of the neurotransmitters dopamine (DA; IC50=6.5 nM), norepinephrine (NE;IC50=1.7 nM), and serotonin (5-HT;IC50=11 nM), and with potentials as an anti-obesity agent . Tesofensine is a CNS acting anti-obesity agent .
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Cat. No.: HY-117167
CAS No.: 219691-94-8
Research Areas:  

Cancer

KB-141 is a potent and selective TRβ agonist. The IC50 values are 23.9 nM and 3.3 nM for binding affinities from displacement of T3 from hTRα1 and hTRβ1, respectively. KB-141 has anti-obesity, anti-diabetic, and lipid-lowering effects?and can be used as an anti-cholesteremic agent in vivo .
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Cat. No.: HY-N4103R
CAS No.: 17605-67-3
Fucosterol (Standard) is the analytical standard of Fucosterol. This product is intended for research and analytical applications. Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research .
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Cat. No.: HY-A0175
CAS No.: 35941-65-2
Synonyms: Butriptylene
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Butriptyline (Butriptylene) is an orally active tricyclic antidepressant that slightly enhances central 5-HT effects. Butriptyline does not inhibit brain norepinephrine uptake. Butriptyline can be used for depression research .
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Cat. No.: HY-136124
CAS No.: 890655-08-0
Target:  

Drug Metabolite

Research Areas:  

Others

Cetilistat impurity 1 is an impurity of Cetilistat. Cetilistat, an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively .
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Cat. No.: HY-P10380A
palm11-PrRP31 TFA is a lipidized endogenous appetite inhibitory neuropeptide (PrRP) analogue. palm11-PrRP31 TFA is GPR10 (EC50=39 pM) and NPFF-R2 effective dual agonists. palm11-PrRP31 TFA is able to mimic the natural function of PrRP by binding to these receptors to reduce food intake. palm11-PrRP31 TFA can be used as a potential anti-obesity agent and for the study of neuropeptide-receptor interaction .
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Cat. No.: HY-149593
CAS No.: 1207036-87-0
Research Areas:  

Metabolic Disease

VU0506013 is a selective positive allosteric modulator of Y4R (KB = 34.9 nM). VU0506013 can be used in the development of anti-obesity agents targeting Y4R .
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Cat. No.: HY-110034
CAS No.: 84484-78-6
Synonyms: BTS 54-505
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Didesmethylsibutramine (BTS 54-505) hydrochloride is the primary amine metabolite of Sibutramine (antidepressant and anti-obesity agent). Didesmethylsibutramine hydrochloride inhibits NMDA-evoked activity. Didesmethylsibutramine hydrochloride is also a reuptake inhibitor. Didesmethylsibutramine hydrochloride induces thermogenesis .
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