palm11-PrRP31 TFA
Based on 1 Customer Validation
palm11-PrRP31 TFA is a lipidized endogenous appetite inhibitory neuropeptide (PrRP) analogue. palm11-PrRP31 TFA is GPR10 (EC50=39 pM) and NPFF-R2 effective dual agonists. palm11-PrRP31 TFA is able to mimic the natural function of PrRP by binding to these receptors to reduce food intake. palm11-PrRP31 TFA can be used as a potential anti-obesity agent and for the study of neuropeptide-receptor interaction.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.44%
- Fòrmula: C181H289N55O46S·xC2HF3O2
- Peso molecular:4003.64 (free base)
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Actividad biológica
Chemical Information
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Appearance Solid
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Peso molecular 4003.64 (free base)
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Fòrmula C181H289N55O46S·xC2HF3O2
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Color White to off-white
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SMILES
O=C(NCCCC[C@@H](C(N[C@@H]([C@H](O)C)C(N1[C@@H](CCC1)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC7=CC=CC=C7)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](CCSC)NC([C@H](CO)NC([C@H](CC8=CNC=N8)NC([C@H](CCCNC(N)=N)NC([C@H](CC9=CNC=N9)NC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC([C@H](CO)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCC)=O.O=C(O)C(F)(F)F.[x]
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Sequence
Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-{Lys(N-γGlu(N-palm))}-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2
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Sequence Shortening
SRTHRHSMEI-{Lys(N-γGlu(N-palm))}-TPDINPAWYASRGIRPVGRF-NH2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
DMSO : 2 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Pureza y Documentación
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Ficha de datos (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)