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hydrazine

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57

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8

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13

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112053
    DPPH
    45+ Cited Publications

    2,2-Diphenyl-1-picrylhydrazyl

    		 Reactive Oxygen Species (ROS) Metabolic Disease
    DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
    DPPH
  • HY-151644
    Fluorescein hydrazide
    1 Publications Verification

    		 Fluorescent Dye Others
    Fluorescein hydrazide is a sensitive fluorescent probe for Hg 2+ and Co 2+ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM [2][3].
    Fluorescein hydrazide
  • HY-W273413
    4-Hydrazino-7-nitro-benzofurazan hydrazine adduct

    NBD-H

    		 Fluorescent Dye Cancer
    4-Hydrazino-7-nitro-benzofurazan hydrazine adduct (NBD-H) is a fluorescent reagent used for protein labeling .
    4-Hydrazino-7-nitro-benzofurazan hydrazine adduct
  • HY-Y0373
    tert-Butyl carbazate

    		Biochemical Assay Reagents Drug Intermediate Infection
    tert-Butyl carbazate serves as a starting material for the preparation of heterocyclic and hydrazine derivatives. tert-Butyl carbazate undergoes coupling with aryl, heteroaryl, and alkenyl boronic acids to synthesize doubly protected monosubstituted hydrazines. Derivatives of tert-Butyl carbazate exhibit varying degrees of inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, and various fungi .
    tert-Butyl carbazate
  • HY-N7065
    Dihydralazine sulfate

    		Drug Derivative Cardiovascular Disease Neurological Disease
    Dihydralazine sulfate is an antihypertensive hydrazine derivative and also a low-potency genotoxic agent. Dihydralazine sulfate is a direct-acting mutagen with a mixed gene mutation mechanism, which induces DNA fragmentation in the lung, kidney and spleen of mice, and induces sister chromatid exchange in mouse bone marrow cells. Dihydralazine sulfate specifically kills DNA repair-deficient bacteria. Dihydralazine sulfate is a vasodilator and antihypertensive agent that reduces systemic vascular resistance, increases cardiac output and heart rate, thereby lowering blood pressure. Dihydralazine sulfate can be used in research related to hypertension and severe early-onset preeclampsia .
    Dihydralazine sulfate
  • HY-W115752
    Hydrazine sulfate (99%)

    Diamine sulfate (99%)

    		 PEPCK Aldehyde Dehydrogenase (ALDH) Neurological Disease Metabolic Disease Cancer
    Hydrazine sulfate is an orally active PEPCK inhibitor. Hydrazine sulfate inhibits PEPCK and low-Km ALDH. Hydrazine sulfate impairs gluconeogenesis and enhances the protective effect of energy substrates against MPP + toxicity. Hydrazine sulfate exacerbates liver damage in rats when combined with Ethanol. Hydrazine sulfate can be used in the research of shock, non-small cell lung cancer, colorectal cancer and Parkinson's disease .
    Hydrazine sulfate (99%)
  • HY-136135
    (2-pyridyldithio)-PEG1-hydrazine

    		ADC Linker Cancer
    (2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    (2-pyridyldithio)-PEG1-hydrazine
  • HY-124197
    Coumarin hydrazine

    		Fluorescent Dye Others
    Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .
    Coumarin hydrazine
  • HY-W000438
    N-Boc-O-tosyl hydroxylamine

    		Amino Acid Derivatives Others
    N-Boc-O-tosyl hydroxylamine is a safe and efficient nitrogen source for N-amination of aryl and alkyl amines. N-Boc-O-tosyl hydroxylamine promotes electrophilic N-amination of aryl amines and alkyl amines to generate β-Boc-protected aryl hydrazines and alkyl hydrazines .
    N-Boc-O-tosyl hydroxylamine
  • HY-W017425
    N'-Phenylacetohydrazide

    Phenylhydrazine acetate

    		 Biochemical Assay Reagents Others
    N'-Phenylacetohydrazide consists of a phenyl group attached to the acetylhydrazide functional group via a hydrazine bond. This compound is commonly used as a reagent in organic chemistry for the determination of carbonyl compounds such as aldehydes and ketones.
    N'-Phenylacetohydrazide
  • HY-112053R
    DPPH (Standard)

    2,2-Diphenyl-1-picrylhydrazyl (Standard)

    		 Reactive Oxygen Species (ROS) Reference Standards Metabolic Disease
    DPPH (Standard) is the analytical standard of DPPH. This product is intended for research and analytical applications. DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
    DPPH (Standard)
  • HY-W009411
    Dansyl hydrazine

    		Fluorescent Dye Others
    Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease .
    Dansyl hydrazine
  • HY-78699
    2-Hydrazinobenzothiazole

    		Indoleamine 2,3-Dioxygenase (IDO) Inflammation/Immunology
    2-Hydrazinobenzothiazole is a potent IDO1 inhibitor with an IC50 of 8 μM. 2-hydrazinobenzothiazole interacts with the IDO1 haem through hydrazine. 2-hydrazinobenzothiazole has the potential for immune system related diseases research .
    2-Hydrazinobenzothiazole
  • HY-W006381
    (3,4-Dimethoxyphenyl)hydrazine hydrochloride

    		Drug Intermediate Others
    (3,4-Dimethoxyphenyl)hydrazine hydrochloride is a drug intermediate for synthesis of various active compounds.
    (3,4-Dimethoxyphenyl)hydrazine hydrochloride
  • HY-118262
    Resorufin acetate

    		Fluorescent Dye Others
    Resorufin acetate is a fluorescent dye that selectively detects hydrazine .
    Resorufin acetate
  • HY-155908
    DSPE-PEG10000-Amine ammonium

    DSPE-PEG10000-NH2 ammonium

    		 Liposome Others
    DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
    DSPE-PEG10000-Amine ammonium
  • HY-128961
    MC-Alkyl-Hydrazine Modified MMAF

    		Drug-Linker Conjugates for ADC Cancer
    MC-Alkyl-Hydrazine Modified MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine .
    MC-Alkyl-Hydrazine Modified MMAF
  • HY-148146
    Phenoxypropazine

    		Monoamine Oxidase Neurological Disease
    Phenoxypropazine is a potent monoamine oxidase (MAO) inhibitor. Phenoxypropazine can be used in research of depression .
    Phenoxypropazine
  • HY-60165
    Pyrazine-2-carbaldehyde

    		Drug Intermediate Others
    Pyrazine-2-carbaldehyde is a heterocyclic aromatic carbaldehyde and can be used as a drug intermediate.
    Pyrazine-2-carbaldehyde
  • HY-D2502
    Cy7 hydrazide

    		Fluorescent Dye Others
    Cy7 hydrazide is a Cy7 (HY-D0825) dye derivative with hydrazine functionality. The hydrazide group of Cy7 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
    Cy7 hydrazide
  • HY-W015012
    NBD-Hydrazine

    		Fluorescent Dye Others
    NBD-Hydrazine is an aldehyde- and ketone-reactive fluorescent probe. NBD-Hydrazine has excitation/emission maxima of 468/535 nm in the presence of aldehydes or ketones. NBD-Hydrazine can be used as a starting material to synthesize malondialdehyde-reactive fluorescent probes. NBD-Hydrazine is a synthetic intermediate in the synthesis of cupric and chronic ion colorimetric sensors .
    NBD-Hydrazine
  • HY-151786
    Fmoc-L-Lys(Pentynoyl-DIM)-OH

    		ADC Linker Others
    Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Lys(Pentynoyl-DIM)-OH
  • HY-136473
    CTX-0124143

    		Histone Acetyltransferase Cancer
    CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton .
    CTX-0124143
  • HY-15608R
    MPTP hydrochloride (Standard)

    		Reference Standards Dopamine Receptor Apoptosis Neurological Disease Cancer
    Iproniazid (phosphate) (Standard) is the analytical standard of Iproniazid (phosphate). This product is intended for research and analytical applications. Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity .
    MPTP hydrochloride (Standard)
  • HY-W013140A
    Azomethine-H sodium hydrate

    Azomethine-H monosodium salt hydrate

    		 Biochemical Assay Reagents Others
    Azomethine-H sodium hydrate is a compound belonging to the class of organic compounds. It is a derivative of hydrazine and is commonly used as a reducing agent in various industrial and biomedical applications. Azomethine-H sodium hydrate is particularly suitable for the reduction of ketones and aldehydes, making it valuable in organic synthesis reactions. It is also used in the production of medicines, dyes, and other chemical products.
    Azomethine-H sodium hydrate
  • HY-W041885R
    Diisopropyl hydrazine-1,2-dicarboxylate (Standard)

    hydrazine-1,2-dicarboxylic Acid Diisopropyl Ester (Standard)

    		 Reference Standards
    Diisopropyl hydrazine-1,2-dicarboxylate (Standard) is the analytical standard of Diisopropyl hydrazine-1,2-dicarboxylate. This product is intended for research and analytical applications.
    Diisopropyl hydrazine-1,2-dicarboxylate (Standard)
  • HY-76214
    Dibenzyl hydrazodicarboxylate

    Dibenzyl hydrazine-1,2-dicarboxylate

    		 Biochemical Assay Reagents Others
    Dibenzyl hydrazodicarboxylate (Dibenzyl hydrazine-1,2-dicarboxylate) is a protein cross-linking agent.
    Dibenzyl hydrazodicarboxylate
  • HY-153566
    JAK1-IN-10

    		JAK Cancer
    JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, is a potent and selective JAK1 inhibitor .
    JAK1-IN-10
  • HY-135301
    Flavanone hydrazone

    		Others Inflammation/Immunology
    Flavanone hydrazine is a potent non-steroidal anti-inflammatory agent. Flavanone hydrazine effectively inhibits lens protein-induced ocular inflammation .
    Flavanone hydrazone
  • HY-W1049075E
    mPEG-pALD (MW 2000)

    		Biochemical Assay Reagents Others
    mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
    mPEG-pALD (MW 2000)
  • HY-149404
    Tyrosinase-IN-12

    		Reactive Oxygen Species (ROS) Tyrosinase Others
    Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 µM and Ki value of 31.25 ± 0.25 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors .
    Tyrosinase-IN-12
  • HY-W1049075B
    mPEG10000-Pald

    		Biochemical Assay Reagents Others
    mPEG10000-Pald is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
    mPEG10000-Pald
  • HY-W1049075D
    mPEG40000-pALD

    		Biochemical Assay Reagents Others
    mPEG40000-pALD is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
    mPEG40000-pALD
  • HY-106471
    Pildralazine

    Propyldazine

    		 Others Cardiovascular Disease
    Pildralazine (Propyldazine) is a hydralazinelike antihypertensive vasodilator containing a free hydrazine group. Pildralazine is orally active, has no significant carcinogenicity in mice model .
    Pildralazine
  • HY-W777037
    2,3-Dichlorobenzamidyl Guanidine-13C2

    		Isotope-Labeled Compounds Others
    2,3-Dichlorobenzamidyl Guanidine- 13C2 is the 13C-labeled 2-(2,3-Dichlorobenzoyl)hydrazine-1-carboximidamide (HY-W727201).
    2,3-Dichlorobenzamidyl Guanidine-13C2
  • HY-W591969
    Benzyl (6-oxohexyl)carbamate

    		Biochemical Assay Reagents Others
    Benzyl (6-oxohexyl)carbamate is a linker containing an aldehyde group and a benzyl (Cbz) protecting group. The aldehyde can react with hydrazine or hydrazide to form a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
    Benzyl (6-oxohexyl)carbamate
  • HY-W800657
    Azido-PEG1-hydrazide hydrochloride

    		Biochemical Assay Reagents Others
    Azido-PEG1-hydrazide hydrochloride is a bifunctional PEG linker containing an azide group and a hydrazide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds.
    Azido-PEG1-hydrazide hydrochloride
  • HY-157571S
    N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8

    		Isotope-Labeled Compounds Cancer
    N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8 is a stable isotope of hydrazine impurities in Sonidegib (HY-16582A).
    N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8
  • HY-D2388
    Sulfo CY5.5 hydrazide

    		Fluorescent Dye Others
    Sulfo Cy5.5-hydrazide is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
    Sulfo CY5.5 hydrazide
  • HY-D1861
    Sulfo-Cy3 hydrazide

    		Fluorescent Dye Others
    Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
    Sulfo-Cy3 hydrazide
  • HY-151787
    Fmoc-L-Lys(N3-Aca-DIM)-OH

    		ADC Linker Others
    Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Lys(N3-Aca-DIM)-OH
  • HY-124197S
    Coumarin hydrazine-d7

    		Isotope-Labeled Compounds Fluorescent Dye Others
    Coumarin hydrazine-d7 is the deuterium labeled Coumarin hydrazine (HY-124197). Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .
    Coumarin hydrazine-d7
  • HY-W009411S
    Dansyl hydrazine-13C2

    		Isotope-Labeled Compounds Fluorescent Dye Others
    Dansyl hydrazine- 13C2 is the 13C-labeled Dansyl hydrazine (HY-W009411). Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease.
    Dansyl hydrazine-13C2
  • HY-W285050
    (Naphthalen-1-ylmethyl)hydrazine hydrochloride

    		Biochemical Assay Reagents Others
    (Naphthalen-1-ylmethyl)hydrazine hydrochloride is a kind of biological materials or organic compounds that are widely used in life science research.
    (Naphthalen-1-ylmethyl)hydrazine hydrochloride
  • HY-W666088
    (2-Phenylethyl)hydrazine dihydrochloride

    		Biochemical Assay Reagents Others
    (2-Phenylethyl)hydrazine (dihydrochloride) is a compound with protective effects against γ-radiation. At a dose of 60 mg/kg, it can increase the survival rate of mice exposed to γ-radiation .
    (2-Phenylethyl)hydrazine dihydrochloride
  • HY-W112332
    1,2-Bis(pyridin-4-ylmethylene)hydrazine

    Isonicotinaldehyde, azine

    		 MOFs Others
    1,2-Bis(pyridin-4-ylmethylene)hydrazine (Isonicotinaldehyde, azine) is a metal-organic framework (MOF).
    1,2-Bis(pyridin-4-ylmethylene)hydrazine
  • HY-W112332A
    (1E,2E)-1,2-Bis(pyridin-4-ylmethylene)hydrazine

    		MOFs Others
    (1E,2E)-1,2-Bis(pyridin-4-ylmethylene)hydrazine is a metal-organic framework (MOF).
    (1E,2E)-1,2-Bis(pyridin-4-ylmethylene)hydrazine
  • HY-W249353
    (1E,2E)-1,2-Bis((1H-imidazol-5-yl)methylene)hydrazine

    		MOFs Others
    (1E,2E)-1,2-Bis((1H-imidazol-5-yl)methylene)hydrazine is a metal-organic framework (MOF).
    (1E,2E)-1,2-Bis((1H-imidazol-5-yl)methylene)hydrazine
  • HY-W837135
    5-Hydrazinyl thalidomide hydrochloride

    		Ligands for E3 Ligase Cancer
    5-Hydrazinyl thalidomide hydrochloride is a Thalidomide analogue featuring a hydrazine. PROTAC linkers are made to recruit E3 ligase for the ubiquitinylation of target proteins. The hydrazine may be used for further derivatization via reactions with various carbonyl groups.
    5-Hydrazinyl thalidomide hydrochloride
  • HY-W1049075H
    mPEG-pALD (MW 3400)

    		Biochemical Assay Reagents Others
    mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
    mPEG-pALD (MW 3400)

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