Tyrosinase-IN-12
Based on 1 Customer Validation
Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 µM and Ki value of 31.25 ± 0.25 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 1860779-42-5
- Formula: C16H12ClN3S
- Molecular Weight:313.80
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) (3day) is a potential anti-browning agent for fresh-cut fruits and vegetables[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:fresh-cut potato slices
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Concentration:
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Incubation Time:3 day
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Result:Exhibited browning inhibition effects close to those of kojic acid on fresh-cut potato slices.
Chemical Information
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CAS No. 1860779-42-5
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Appearance Solid
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Molecular Weight 313.80
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Formula C16H12ClN3S
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Color Off-white to light yellow
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SMILES
ClC1=CC=C(/C=N/NC2=NC(C3=CC=CC=C3)=CS2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (159.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1867 mL | 15.9337 mL | 31.8674 mL | 79.6686 mL |
| 5 mM | 0.6373 mL | 3.1867 mL | 6.3735 mL | 15.9337 mL | |
| 10 mM | 0.3187 mL | 1.5934 mL | 3.1867 mL | 7.9669 mL | |
| 15 mM | 0.2124 mL | 1.0622 mL | 2.1245 mL | 5.3112 mL | |
| 20 mM | 0.1593 mL | 0.7967 mL | 1.5934 mL | 3.9834 mL | |
| 25 mM | 0.1275 mL | 0.6373 mL | 1.2747 mL | 3.1867 mL | |
| 30 mM | 0.1062 mL | 0.5311 mL | 1.0622 mL | 2.6556 mL | |
| 40 mM | 0.0797 mL | 0.3983 mL | 0.7967 mL | 1.9917 mL | |
| 50 mM | 0.0637 mL | 0.3187 mL | 0.6373 mL | 1.5934 mL | |
| 60 mM | 0.0531 mL | 0.2656 mL | 0.5311 mL | 1.3278 mL | |
| 80 mM | 0.0398 mL | 0.1992 mL | 0.3983 mL | 0.9959 mL | |
| 100 mM | 0.0319 mL | 0.1593 mL | 0.3187 mL | 0.7967 mL |
Tyrosinase-IN-12 Related Classifications
HY-149404 Related Classifications
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