1. Antibody-drug Conjugate/ADC Related
    Cell Cycle/DNA Damage
    Cytoskeleton
  2. Drug-Linker Conjugates for ADC
    Microtubule/Tubulin
  3. MC-Alkyl-Hydrazine Modified MMAF

MC-Alkyl-Hydrazine Modified MMAF 

Cat. No.: HY-128961
Handling Instructions

MC-Alkyl-Hydrazine Modified MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine.

For research use only. We do not sell to patients.

MC-Alkyl-Hydrazine Modified MMAF Chemical Structure

MC-Alkyl-Hydrazine Modified MMAF Chemical Structure

CAS No. : 1404071-64-2

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Description

MC-Alkyl-Hydrazine Modified MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine[1].

IC50 & Target[1]

Auristatin

 

Molecular Weight

1133.42

Formula

C₅₉H₉₂N₁₀O₁₂

CAS No.

1404071-64-2

SMILES

O=C(N1CCCCO1)[[email protected]@H](NC([[email protected]](C)[[email protected]]([[email protected]@]2([H])N(CCC2)C(C[[email protected]@H](OC)[[email protected]@]([[email protected]@H](C)CC)([H])N(C)C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C)CCCC(NNC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45

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MC-Alkyl-Hydrazine Modified MMAF
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HY-128961
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