Fluorescein hydrazide
Based on 1 publication(s) in Google Scholar
Fluorescein hydrazide is a sensitive fluorescent probe for Hg2+ and Co2+ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM[2][3].
For research use only. We do not sell to patients.
- Purity: 99.31%
- CAS No.: 78044-20-9
- Formula: C20H14N2O4
- Molecular Weight:346.34
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Fluorescein hydrazide
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Biological Activity
Fluorescein hydrazide forms a complex with Hg2+, which in turn triggers structural changes in the Fluorescein hydrazide molecule, causes changes in its absorption and fluorescence spectra, thereby resulting the color and fluorescence intensity of Fluorescein hydrazide solution[2].
Fluorescein hydrazide can be used for detection of mercury pollution in water, food and biological samples, which can be applied in environmental monitoring, food safety and biomedicine[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 78044-20-9
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Appearance Solid
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Molecular Weight 346.34
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Formula C20H14N2O4
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Color White to off-white
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SMILES
O=C1C=CC2=C(C3=C(C(NN)=O)C=CC=C3)C4=C(C=C(C=C4)O)OC2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Research (Wash D C)
Isovalerylspiramycin I Reprograms the Immunosuppressive and Temozolomide-Resistant Microenvironment by Inhibiting the Frizzled-5/Wnt/β-Catenin Pathway in Glioblastoma. [Abstract]2025 Aug 13:8:0828. PMID: 40809457
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Yusha Feng, et al. A novel "turn-on" thiooxofluorescein-based colorimetric and fluorescent sensor for Hg2+ and its application in living cells. Talanta. 2017 Aug 1;170:103-110. [Content Brief]
[3]. Mori I, et al., Selective and sensitive fluorometric determinations of cobalt(II) and hydrogen peroxide with fluorescein-hydrazide. Talanta. 1998 Nov;47(3):631-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Fluorescein hydrazide Related Classifications
HY-151644 Related Classifications
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