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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
hyphal growth
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "hyphal growth" in MCE Product Catalog:
Cat. No.: HY-N6784
CAS No.: 11050-94-5
Target:
Synonyms: (Z)-Abienol
Target:
Quinalizarin is a protein kinase CK2 inhibitor with a Ki of 0.052 μM. Quinalizarin exhibits antifungal and anticancer activities. Quinalizarin induces ROS production, apoptotic signaling, mitochondrial pathway activation, cell cycle arrest, and cytotoxicity in cancer cells. Quinalizarin inhibits hyphal growth, biofilm formation, and mature biofilm integrity of Candida albicans. Quinalizarin can be used in research related to cancer and fungal infections .
Cat. No.: HY-P10304A
Synonyms: Cyclo(Pro-Arg) TFA
Cat. No.: HY-N2558
CAS No.: 19668-69-0
Category:
Murraya paniculata (L.) Jack. Rutaceae Coumarins Phenylpropanoids Plants Disease Research Fields Cancer
Target:
Cat. No.: HY-178732
CAS No.: 1463913-43-0
Research Areas:
AB-22, a vinyl sulfate compound, is an orally active antifungal agent. AB-22 inhibits hyphal growth and biofilm initiation by inhibiting the gene expression of ALS3, HWP1, and ECE1 in Candida albicans SC5314 cells. AB-22 can be used for the research of infrction, such as systemic candidiasis .
Cat. No.: HY-120921
CAS No.: 156052-68-5
Synonyms: RH-7281
Target:
Research Areas:
Zoxamide (RH-7281) is an oomycete Fungicide and covalent β-tubulin inhibitor. RH-7281 inhibits the assembly of tubulin into microtubules in vitro. Zoxamide binds covalently to β-tubulin, disrupting microtubule assembly and the cytoskeleton. Zoxamide blocks nuclear division in germinated hyphae of Phytophthora capsici and inhibits hyphal growth of Phytophthora capsici .
Cat. No.: HY-N15600
CAS No.: 68053-32-7
Synonyms: (-)-Merulidial
Category:
Target:
Cat. No.: HY-145873
CAS No.: 2759037-58-4
BI-10 is an antifungal compound. BI-10 combined with Fluconazole can inhibit hyphal growth, result in ROS accumulation, and decrease mitochondrial membrane potential (MMP) as well as altering membrane permeability .
Cat. No.: HY-169202
CAS No.: 3055029-65-4
Antifungal agent 118 (compund C22) inhibits the hyphal growth of V. mali by inducing oxidative damage and disrupting the integrity of the cell membrane .
Cat. No.: HY-161856
Antifungal agent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide against Monilinia fructicola. Antifungal agent 106 exhibits antifungal activity with an EC50 value of 11.8 mg/L. It affects hyphal growth by disrupting cell membrane integrity, leading to increased membrane permeability and release of intracellular electrolytes. Antifungal agent 106 can be used in research related to brown rot of stone fruits .
Cat. No.: HY-178051
Target:
Research Areas:
Antifungal agent 135 (Compound C2), an antifungal agent, is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.99 μM. Antifungal agent 135 has potent antifungal activities against Valsa mali, Sclerotinia sclerotiorum and Phytophthora capsici with EC50 s of 0.280, 1.11 and 0.130 mg/L, respectively. Antifungal agent 135 shows protective and curative activities against Phytophthora capsici and Valsa mali by effectively disrupting hyphal structural integrity and inhibiting mycelial growth .
Cat. No.: HY-183759
CAS No.: 2132414-06-1
Synonyms: SYN551769
Feneptamidoquin (SYN551769) is a quinoline Fungicide. The combination of Feneptamidoquin and Eugenol (HY-N0337) potently inhibits mycelial growth of Botrytis cinerea. Feneptamidoquin can be used in studies related to gray mold .
Cat. No.: HY-184728
Antifungal agent-169 (compound 5p) is an antifungal agent that inhibits fluconazole (HY-B0101)-susceptible Candida albicans SC5314 with an MIC50 of 0.28 μM. Antifungal agent-169 reduces the expression levels of cAMP-PKA pathway-related genes including RAS1, EFG1, BCR1, ECE1 and HWP1 in Candida albicans. Antifungal agent-169 inhibits biofilm formation and hyphal growth of Candida albicans. Antifungal agent-169 can be used in studies related to Candida albicans infection .
Cat. No.: HY-N19791
CAS No.: 13410-15-6
Category:
Monophenols Coumarins Phenols Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Phenylpropanoids Plants Umbelliferae
Target:
Cat. No.: HY-W102893
CAS No.: 99910-50-6
Category:
Cat. No.: HY-181610
CAS No.: 3112883-32-3
Target:
Research Areas:
SDH-IN-45 is a succinate dehydrogenase BcSDH inhibitor and mycelial growth inhibitor targeting Botrytis cinerea, with an IC50 of 5.97 μg/mL against Botrytis cinerea. SDH-IN-45 inhibits succinate dehydrogenase, a component of the mitochondrial electron transport chain, via a unique binding mode, thereby regulating fungal energy metabolism. SDH-IN-45 causes morphological damage to Botrytis cinerea mycelia, leading to collapse and shrinkage of mycelial structures. SDH-IN-45 exhibits in vitro fungicidal activity against Botrytis cinerea. SDH-IN-45 can be used in research related to cucumber gray mold .
Cat. No.: HY-181346
CAS No.: 3103433-67-3
Target:
Research Areas:
SDH-IN-44 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 12.5 μg/mL against Alternaria solani. SDH-IN-44 exhibits antifungal activity and inhibits fungal mycelial growth. SDH-IN-44 is applicable to research related to fungal infections .
Cat. No.: HY-187509
Target:
Research Areas:
Succinate dehydrogenase-IN-13 is a succinate dehydrogenase inhibitor with an IC50 of 8.69 μM against Rhizoctonia solani. Succinate dehydrogenase-IN-13 binds stably within the succinate dehydrogenase active site to disrupt fungal respiration and energy metabolism, and induces hyphal distortion and mitochondrial damage in Rhizoctonia solani. Succinate dehydrogenase-IN-13 reduces intracellular ATP levels in Rhizoctonia solani mycelia. Succinate dehydrogenase-IN-13 can be used for the research of Rhizoctonia solani infection, Botrytis cinerea infection .
Cat. No.: HY-183722
Target:
Research Areas:
SDH-IN-46 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 1.21 μM. SDH-IN-46 disrupts fungal respiration via mitochondrial respiratory chain enzyme targeting and exhibits broad-spectrum antifungal activity. SDH-IN-46 exhibits substantial protective effects against S. sclerotiorum on oilseed rape leaves, Rhizoctonia solani on rice leaves, and Valsa mali on apple fruits .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
