Antifungal agent 106
Antifungal agent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide against Monilinia fructicola. Antifungal agent 106 exhibits antifungal activity with an EC50 value of 11.8 mg/L. It affects hyphal growth by disrupting cell membrane integrity, leading to increased membrane permeability and release of intracellular electrolytes. Antifungal agent 106 can be used in research related to brown rot of stone fruits.
For research use only. We do not sell to patients.
- Formula: C20H21BrFN3O2
- Molecular Weight:434.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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mTOR 0.8 μM (IC50) |
Antifungal agent 106 (3.125-50 mg/L) exhibits inhibitory activity against M. fructicola, inhibiting spore germination and mycelial formation. It induces the production of excess endogenous reactive oxygen species (ROS) in M. fructicola, leading to oxidative damage, enzyme inactivation, and cell membrane disruption[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 434.30
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Formula C20H21BrFN3O2
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SMILES
BrC1=CC=C(C(C(NC2=CC=CC(F)=C2)=O)N3CCN(C(C)=O)CC3)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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