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Results for "

plant sesquiterpene

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (5) Apoptosis (3) Autophagy (1) Bacterial (4) COX (1) Ferroptosis (4) Fungal (1) Glutathione Peroxidase (1) HCV (4) Insecticide (2) Interleukin Related (1) Isotope-Labeled Compounds (1) Microtubule/Tubulin (1) mTOR (1) NF-κB (1) NO Synthase (1) p38 MAPK (1) Parasite (5) PI3K (1) Platelet-activating Factor Receptor (PAFR) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2) TNF Receptor (1)
By Research Areas:	Cancer (11) Cardiovascular Disease (3) Infection (13) Inflammation/Immunology (5) Metabolic Disease (3) Neurological Disease (4)

By Targets:

Akt (5)

Apoptosis (3)

Autophagy (1)

Bacterial (4)

COX (1)

Ferroptosis (4)

Fungal (1)

Glutathione Peroxidase (1)

HCV (4)

Insecticide (2)

Interleukin Related (1)

Isotope-Labeled Compounds (1)

Microtubule/Tubulin (1)

mTOR (1)

NF-κB (1)

NO Synthase (1)

p38 MAPK (1)

Parasite (5)

PI3K (1)

Platelet-activating Factor Receptor (PAFR) (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (2)

TNF Receptor (1)

By Research Areas:

Cancer (11)

Cardiovascular Disease (3)

Infection (13)

Inflammation/Immunology (5)

Metabolic Disease (3)

Neurological Disease (4)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0094

Artemisinin 30+ Cited Publications Qinghaosu; NSC 369397	HCV Parasite Akt Ferroptosis	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-N3651

Curzerenone 1 Publications Verification	Bacterial Reactive Oxygen Species (ROS) Apoptosis PI3K Akt mTOR	Infection Cancer
Curzerenone is an orally active sesquiterpene compound and Antibacterial agent. Curzerenone can be isolated from Curcuma zedoaria and Curcuma aeruginosa plants. Curzerenone increases ROS levels, activates Apoptotic signaling pathways, and attenuates the PI3K/AKT/mTOR signaling pathway. Curzerenone exhibits anticancer activity against liver cancer and cervical cancer. Curzerenone has antioxidant effects. Curzerenone shows weak antibacterial activity against Escherichia coli. Curzerenone can be used in research related to hepatocellular carcinoma, cervical cancer, and Escherichia coli infection .

HY-B0094R

Artemisinin (Standard) Qinghaosu (Standard); NSC 369397 (Standard)	Reference Standards HCV Parasite Akt Ferroptosis	Infection Neurological Disease Cancer
Artemisinin (Standard) is the analytical standard of Artemisinin. This product is intended for research and analytical applications. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-N1944A

cis-Nerolidol	Bacterial	Infection
cis-Nerolidol is a sesquiterpene alcohol that can be found in various plants. cis-Nerolidol exhibits antioxidant and antibacterial activities. cis-Nerolidol can also potentiate the action of antibiotics .

HY-N8371

Shizukaol B	NO Synthase COX Interleukin Related TNF Receptor	Inflammation/Immunology
Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression .

HY-N16388

α-Costic acid	Autophagy Parasite	Infection
α-Costic acid is a plant sesquiterpene that can induce oxidative stress and autophagy in tomatoes. α-Costic acid has acaricidal activity .

HY-115363

Curcumenone	Others	Cardiovascular Disease Metabolic Disease
Curcumenone is a major constituent of the plants of medicinally important genus of Curcuma. Curcumenone, a caraborane type sesquiterpene has been reported to be a vasorelaxant, hepatoprotective and an effective inhibitor of intoxication .

HY-B0094S

Artemisinin-d3 Qinghaosu-d₃; NSC 369397-d₃	Akt Ferroptosis HCV Parasite	Infection Neurological Disease Cancer
Artemisinin-d₃ is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-W585959

(E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene	Insecticide	Infection
(E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene (TMTT), a sesquiterpene, is the major herbivore-induced plant volatile that help in defense directly by acting as repellants and indirectly by recruiting insects' natural enemies. (E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene attractes Asian corn borer (ACB, Ostrinia furnacalis) larvae. External supplementation with (E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene hampered the larvae's ability to locate pre-infested maize .

HY-N8442

Drimenol (-)-Drimenol	Others	Others
Drimenol is a drimane-type sesquiterpene that can be isolated from Valerian plant .

HY-123091

Ivangustin	Others	Cancer
Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica .

HY-118019

Scandenolide	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
Scandenolide is a sesquiterpene lactone that can be found in Philippines medicinal plant Mikania cordata. Scandenolide inhibits leukotriene and platelet activating factor synthesis in leukocytes .

HY-N11800

Transilin	Others	Others
Transilin is a sesquiterpene lactone. Transilin can be isolated from the whole plant of Lepisorus contortus (Christ) Ching .

HY-N8864

Isosativenediol	Others	Others
Isosativenediol is a sesquiterpene compound. Isosativenediol can be purified from Cochliobolus sativus, an endophytic fungus isolated from the desert plant Artemisia Desertorum .

HY-N1300

Shizukanolide F	Fungal	Infection Cancer
Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic fungi and anti-metastasis breast cancer .

HY-N1944AR

cis-Nerolidol (Standard)	Reference Standards Bacterial	Infection
cis-Nerolidol (Standard) is the analytical standard of cis-Nerolidol. This product is intended for research and analytical applications. cis-Nerolidol is a sesquiterpene alcohol that can be found in various plants. cis-Nerolidol exhibits antioxidant and antibacterial activities. cis-Nerolidol can also potentiate the action of antibiotics .

HY-126758

Ludartin	Apoptosis Glutathione Peroxidase	Inflammation/Immunology
Ludartin a sesquiterpene lactone, which can be isolated from the plant Artemisia carruthii Wood. Ludartin reduces the expression of myeloperoxidase and malondialdehyde, enhances the expression of glutathione and superoxide dismutase in spinal cord tissue. Ludartin inhibits neuronal apoptosis. Ludartin inhibits the upregulation of tumor necrosis factor-α, interleukin-1β, and interleukin-6. Ludartin improves the motor function of rats with spinal cord injury .

HY-B0094S3

Artemisinin-13C,d4 Qinghaosu-¹³C,d₄; NSC 369397-13C,d₄	Ferroptosis Akt Parasite HCV Isotope-Labeled Compounds	Infection Neurological Disease Cancer
Artemisinin- ¹³C,d₄ is ¹³C and deuterated labeled Artemisinin (HY-B0094). Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-W749442

7a-Hydroxyfrullanolide	Microtubule/Tubulin	Cancer
7a-Hydroxyfrullanolide has anticancer properties. 7a-Hydroxyfrullanolide reduces polymerization of α-, β-tubulin. 7a-Hydroxyfrullanolide preferrs to bind to β-tubulin over α-tubulin. 7a-Hydroxyfrullanolide also triggers DNA damage response arrests cells in the G2/M-phase. 7a-Hydroxyfrullanolide is an eudesmanolide sesquiterpene lactone (SL) and can be isolated from the flowering plants of the Asteraceae family .

HY-N18171

Caryophyllene	Others	Infection Inflammation/Immunology Cancer
Caryophyllene is a macrocyclic sesquiterpene alkene present in the essential oil of Artemisia annua, with anti-inflammatory and anticancer activities. Caryophyllene plays a role in the plant defense of Artemisia annua .

HY-N19153

Minimolide L	Others	Cancer
Minimolide L is a sesquiterpene lactone. Minimolide L can be isolated from the whole plant of Centipeda minima. Minimolide L does not inhibit nitric oxide production. Minimolide L exhibits no anticancer activity against liver cancer, colorectal cancer, and cervical cancer .

HY-N16977

6β,8-Dihydroxyeremophil-7(11)-en-12,8-olide	Others	Others
6β,8-Dihydroxyeremophil-7(11)-en-12,8-olide is an eremophilane-type sesquiterpene lactone compound, and eremophilane-type sesquiterpenes are the main secondary metabolites of Ligularia genus plants. 6β,8-Dihydroxyeremophil-7(11)-en-12,8-olide can be naturally extracted from the dried roots of Ligularia virgaurea (Maxim.) Mattf .

HY-135873

Germacrene B	Bacterial	Infection
Germacrene B is a central intermediate in sesquiterpene biosynthesis. Germacrene B has been ascribed a warm, sweet, woody-spicy, geranium-like odour and is an important flavour constituent of lime peel oil. Germacrene B is also one of the main constituents of the essential oils from different plants that have antibacterial activity.

HY-N12558

β-Elemenone	Others	Others
β-Elemenone is a volatile sesquiterpene found in Curcuma wenyujin Y.H. Chen et C. Ling. and Curcuma longa L. 35-1 rhizomes. Terpenoids are the most abundant and structurally diverse natural products found in numerous plants, exhibiting broad and significant pharmacological properties in the treatment of cancer, malaria, inflammation, and various infectious diseases .

HY-125778

Cochlioquinone B	Others	Metabolic Disease
Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.

HY-W585885

(3E)-4,8-Dimethylnona-1,3,7-triene	Insecticide	Others
(3E)-4,8-Dimethylnona-1,3,7-triene, a sesquiterpene, is the major herbivore-induced plant volatile that help in defense directly by acting as repellants and indirectly by recruiting insects' natural enemies. (3E)-4,8-Dimethylnona-1,3,7-triene attractes Asian corn borer (ACB, Ostrinia furnacalis) larvae. External supplementation with (3E)-4,8-Dimethylnona-1,3,7-triene hampered the larvae's ability to locate pre-infested maize.

HY-N2423B

(E/Z)-Sinigrin free base (E/Z)-Allyl-glucosinolate free base; (E/Z)-2-Propenyl-glucosinolate free base	NF-κB p38 MAPK Apoptosis	Cardiovascular Disease Infection Inflammation/Immunology Cancer
(E/Z)-Sinigrin ((E/Z)-Allyl-glucosinolate; (E/Z)-2-Propenyl-glucosinolate) free base is an orally active aliphatic thioglucoside anti-leukemia compound. Allyl isothiocyanate, produced by the hydrolysis of (E/Z)-sinigrin free base by myrosinase, has an IC₅₀ of 2.71 μM against HL60 leukemia cells. The hydrolysis products of (E/Z)-sinigrin free base can further activate apoptosis pathways, inhibit NF-κB and MAPK signaling pathways, and induce phase II metabolic enzyme activity, thus exhibiting anti-cancer, anti-inflammatory, antibacterial, antioxidant, and wound healing activities. (E/Z)-Sinigrin free base can be used in research on cancer, inflammation-related diseases (such as atherosclerosis), and infectious diseases. (E/Z)-Sinigrin free base can be naturally extracted from the seeds of Brassica nigra, Brassica juncea, and other Brassicaceae plants such as broccoli and Brussels sprouts. Methyl pechueloate is a guaiane-type sesquiterpene ester compound and a potential precursor of xerantholide. It is useful in the structural elucidation and biosynthetic pathway studies of sesquiterpenoids. Methyl pechueloate can be naturally extracted from the aerial parts of Pechuel-Loeschea leibnitziae (Kuntze) O. Hoffm .

Cat. No.	Product Name

HY-L056

Terpenoids Library	768 compounds
Terpenoids, also known as isoprenoids, are the most numerous and structurally diverse natural products found in many plants. Terpenoids are divided into monoterpenes, sesquiterpenes, diterpenes, sesterpenes, and triterpenes depending on its carbon units. Several studies, in vitro, preclinical, and clinical have confirmed that this class of compounds displays a wide array of very important pharmacological properties in the fight against cancer, malaria, inflammation, and a variety of infectious diseases. Naturally occurring terpenoids provide new opportunities to discover new drugs with minimum side effects. MCE designs a unique collection of 768 terpenoid compounds that all come from natural products. MCE Terpenoids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Terpenoids Library

768 compounds

Terpenoids, also known as isoprenoids, are the most numerous and structurally diverse natural products found in many plants. Terpenoids are divided into monoterpenes, sesquiterpenes, diterpenes, sesterpenes, and triterpenes depending on its carbon units. Several studies, in vitro, preclinical, and clinical have confirmed that this class of compounds displays a wide array of very important pharmacological properties in the fight against cancer, malaria, inflammation, and a variety of infectious diseases. Naturally occurring terpenoids provide new opportunities to discover new drugs with minimum side effects.

MCE designs a unique collection of 768 terpenoid compounds that all come from natural products. MCE Terpenoids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0094

Artemisinin 30+ Cited Publications Qinghaosu; NSC 369397	Infection Structural Classification Piscidia erythrina L. Neurological Disease Classification of Application Fields Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields Source Classification	HCV Parasite Akt Ferroptosis
Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-N3651

Curzerenone 1 Publications Verification	Infection Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Curcuma phaeocaulis Valeton Plants Disease Research Fields Source Classification Zingiberaceae	Bacterial Reactive Oxygen Species (ROS) Apoptosis PI3K Akt mTOR
Curzerenone is an orally active sesquiterpene compound and Antibacterial agent. Curzerenone can be isolated from Curcuma zedoaria and Curcuma aeruginosa plants. Curzerenone increases ROS levels, activates Apoptotic signaling pathways, and attenuates the PI3K/AKT/mTOR signaling pathway. Curzerenone exhibits anticancer activity against liver cancer and cervical cancer. Curzerenone has antioxidant effects. Curzerenone shows weak antibacterial activity against Escherichia coli. Curzerenone can be used in research related to hepatocellular carcinoma, cervical cancer, and Escherichia coli infection .

HY-B0094R

Artemisinin (Standard) Qinghaosu (Standard); NSC 369397 (Standard)	Structural Classification Piscidia erythrina L. Terpenoids Sesquiterpenes Plants Compositae Source Classification	Reference Standards HCV Parasite Akt Ferroptosis
Artemisinin (Standard) is the analytical standard of Artemisinin. This product is intended for research and analytical applications. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-N1944A

cis-Nerolidol	Terpenoids Verbenaceae Sesquiterpenes Plants Lantana camaraLinn. Source Classification	Bacterial
cis-Nerolidol is a sesquiterpene alcohol that can be found in various plants. cis-Nerolidol exhibits antioxidant and antibacterial activities. cis-Nerolidol can also potentiate the action of antibiotics .

HY-N8371

Shizukaol B	Terpenoids Sesquiterpenes Chloranthaceae Plants Source Classification Chloranthus henryi Hemsl.	NO Synthase COX Interleukin Related TNF Receptor
Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression .

HY-N16388

α-Costic acid	Terpenoids Sesquiterpenes Plants Compositae Desmodium sandwicense Source Classification	Autophagy Parasite
α-Costic acid is a plant sesquiterpene that can induce oxidative stress and autophagy in tomatoes. α-Costic acid has acaricidal activity .

HY-115363

Curcumenone	Terpenoids Sesquiterpenes Plants Curcuma phaeocaulis Valeton Source Classification Zingiberaceae	Others
Curcumenone is a major constituent of the plants of medicinally important genus of Curcuma. Curcumenone, a caraborane type sesquiterpene has been reported to be a vasorelaxant, hepatoprotective and an effective inhibitor of intoxication .

HY-W585959

(E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene	Structural Classification Elettaria cardamomum (L.) Maton Terpenoids Sesquiterpenes Plants Source Classification Zingiberaceae	Insecticide
(E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene (TMTT), a sesquiterpene, is the major herbivore-induced plant volatile that help in defense directly by acting as repellants and indirectly by recruiting insects' natural enemies. (E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene attractes Asian corn borer (ACB, Ostrinia furnacalis) larvae. External supplementation with (E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene hampered the larvae's ability to locate pre-infested maize .

HY-N8442

Drimenol (-)-Drimenol	Terpenoids Sesquiterpenes Valeriana officinalis Linn. Plants Valerianaceae Source Classification	Others
Drimenol is a drimane-type sesquiterpene that can be isolated from Valerian plant .

HY-123091

Ivangustin	Classification of Application Fields Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields Piptanthus nepalensis (Hook.) D. Don Source Classification Cancer	Others
Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica .

HY-118019

Scandenolide	Terpenoids Sesquiterpenes Plants Compositae Source Classification Leptoderris fasciculata (Benth.) Dunn	Platelet-activating Factor Receptor (PAFR)
Scandenolide is a sesquiterpene lactone that can be found in Philippines medicinal plant Mikania cordata. Scandenolide inhibits leukotriene and platelet activating factor synthesis in leukocytes .

HY-N11800

Transilin	Flavonoids Lepisorus contortus (Christ) Ching Flavones Polypodiaceae Plants Source Classification	Others
Transilin is a sesquiterpene lactone. Transilin can be isolated from the whole plant of Lepisorus contortus (Christ) Ching .

HY-N8864

Isosativenediol	Terpenoids Sesquiterpenes Millettia erythrocalyx Gagnep. Plants Compositae Source Classification	Others
Isosativenediol is a sesquiterpene compound. Isosativenediol can be purified from Cochliobolus sativus, an endophytic fungus isolated from the desert plant Artemisia Desertorum .

HY-N1300

Shizukanolide F	Chloranthus serratus (Thunb.) Roem. et Schult. Terpenoids Sesquiterpenes Chloranthaceae Plants Source Classification	Fungal
Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic fungi and anti-metastasis breast cancer .

HY-N1944AR

cis-Nerolidol (Standard)	Terpenoids Verbenaceae Sesquiterpenes Plants Lantana camaraLinn. Source Classification	Reference Standards Bacterial
cis-Nerolidol (Standard) is the analytical standard of cis-Nerolidol. This product is intended for research and analytical applications. cis-Nerolidol is a sesquiterpene alcohol that can be found in various plants. cis-Nerolidol exhibits antioxidant and antibacterial activities. cis-Nerolidol can also potentiate the action of antibiotics .

HY-126758

Ludartin	Artemisia sieversiana Ehrhart ex Willd. Plants Compositae Source Classification	Apoptosis Glutathione Peroxidase
Ludartin a sesquiterpene lactone, which can be isolated from the plant Artemisia carruthii Wood. Ludartin reduces the expression of myeloperoxidase and malondialdehyde, enhances the expression of glutathione and superoxide dismutase in spinal cord tissue. Ludartin inhibits neuronal apoptosis. Ludartin inhibits the upregulation of tumor necrosis factor-α, interleukin-1β, and interleukin-6. Ludartin improves the motor function of rats with spinal cord injury .

HY-W749442

7a-Hydroxyfrullanolide	Natural Products Sphaeranthus indicus L. Asteraceae Plants Source Classification	Microtubule/Tubulin
7a-Hydroxyfrullanolide has anticancer properties. 7a-Hydroxyfrullanolide reduces polymerization of α-, β-tubulin. 7a-Hydroxyfrullanolide preferrs to bind to β-tubulin over α-tubulin. 7a-Hydroxyfrullanolide also triggers DNA damage response arrests cells in the G2/M-phase. 7a-Hydroxyfrullanolide is an eudesmanolide sesquiterpene lactone (SL) and can be isolated from the flowering plants of the Asteraceae family .

HY-N18171

Caryophyllene	Structural Classification Natural Products Source Classification	Others
Caryophyllene is a macrocyclic sesquiterpene alkene present in the essential oil of Artemisia annua, with anti-inflammatory and anticancer activities. Caryophyllene plays a role in the plant defense of Artemisia annua .

HY-N19153

Minimolide L	Centipeda minima (L.) A. Braun & Asch. Structural Classification Terpenoids Sesquiterpenes Plants Compositae Source Classification	Others
Minimolide L is a sesquiterpene lactone. Minimolide L can be isolated from the whole plant of Centipeda minima. Minimolide L does not inhibit nitric oxide production. Minimolide L exhibits no anticancer activity against liver cancer, colorectal cancer, and cervical cancer .

HY-N16977

6β,8-Dihydroxyeremophil-7(11)-en-12,8-olide	Structural Classification Terpenoids Sesquiterpenes Asteraceae Plants Ligularia virgaurea (Maxim.) Mattf. Source Classification	Others
6β,8-Dihydroxyeremophil-7(11)-en-12,8-olide is an eremophilane-type sesquiterpene lactone compound, and eremophilane-type sesquiterpenes are the main secondary metabolites of Ligularia genus plants. 6β,8-Dihydroxyeremophil-7(11)-en-12,8-olide can be naturally extracted from the dried roots of Ligularia virgaurea (Maxim.) Mattf .

HY-135873

Germacrene B	Structural Classification Other Monoterpenes Ribes nigrumL. Terpenoids Grossulariaceae Plants Source Classification	Bacterial
Germacrene B is a central intermediate in sesquiterpene biosynthesis. Germacrene B has been ascribed a warm, sweet, woody-spicy, geranium-like odour and is an important flavour constituent of lime peel oil. Germacrene B is also one of the main constituents of the essential oils from different plants that have antibacterial activity.

HY-N12558

β-Elemenone	Structural Classification Terpenoids Sesquiterpenes Curcuma aromatica Salisb. cv. Wenyujin Plants Source Classification Zingiberaceae	Others
β-Elemenone is a volatile sesquiterpene found in Curcuma wenyujin Y.H. Chen et C. Ling. and Curcuma longa L. 35-1 rhizomes. Terpenoids are the most abundant and structurally diverse natural products found in numerous plants, exhibiting broad and significant pharmacological properties in the treatment of cancer, malaria, inflammation, and various infectious diseases .

HY-125778

Cochlioquinone B	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Others
Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.

HY-W585885

(3E)-4,8-Dimethylnona-1,3,7-triene	Structural Classification Natural Products Poaceae Plants Melinis minutiflora P. Beauv. Source Classification	Insecticide
(3E)-4,8-Dimethylnona-1,3,7-triene, a sesquiterpene, is the major herbivore-induced plant volatile that help in defense directly by acting as repellants and indirectly by recruiting insects' natural enemies. (3E)-4,8-Dimethylnona-1,3,7-triene attractes Asian corn borer (ACB, Ostrinia furnacalis) larvae. External supplementation with (3E)-4,8-Dimethylnona-1,3,7-triene hampered the larvae's ability to locate pre-infested maize.

HY-N2423B

(E/Z)-Sinigrin free base (E/Z)-Allyl-glucosinolate free base; (E/Z)-2-Propenyl-glucosinolate free base	Structural Classification Glucosinolates Plants Brassicaceae Source Classification Mutarda nigra (L.) Bernh.	NF-κB p38 MAPK Apoptosis
(E/Z)-Sinigrin ((E/Z)-Allyl-glucosinolate; (E/Z)-2-Propenyl-glucosinolate) free base is an orally active aliphatic thioglucoside anti-leukemia compound. Allyl isothiocyanate, produced by the hydrolysis of (E/Z)-sinigrin free base by myrosinase, has an IC₅₀ of 2.71 μM against HL60 leukemia cells. The hydrolysis products of (E/Z)-sinigrin free base can further activate apoptosis pathways, inhibit NF-κB and MAPK signaling pathways, and induce phase II metabolic enzyme activity, thus exhibiting anti-cancer, anti-inflammatory, antibacterial, antioxidant, and wound healing activities. (E/Z)-Sinigrin free base can be used in research on cancer, inflammation-related diseases (such as atherosclerosis), and infectious diseases. (E/Z)-Sinigrin free base can be naturally extracted from the seeds of Brassica nigra, Brassica juncea, and other Brassicaceae plants such as broccoli and Brussels sprouts. Methyl pechueloate is a guaiane-type sesquiterpene ester compound and a potential precursor of xerantholide. It is useful in the structural elucidation and biosynthetic pathway studies of sesquiterpenoids. Methyl pechueloate can be naturally extracted from the aerial parts of Pechuel-Loeschea leibnitziae (Kuntze) O. Hoffm .

Cat. No.	Product Name	Chemical Structure

HY-B0094S

Artemisinin-d3

Artemisinin-d₃ is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-B0094S3

Artemisinin-13C,d4

Artemisinin- ¹³C,d₄ is ¹³C and deuterated labeled Artemisinin (HY-B0094). Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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plant sesquiterpene

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Screening Libraries

NaturalProducts

Isotope-Labeled Compounds

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