2. Natural Products
  3. Plants Terpenoids
  4. Compositae Sesquiterpenes
  5. Centipeda minima (L.) A. Braun & Asch.
  6. Minimolide L

Minimolide L is a sesquiterpene lactone. Minimolide L can be isolated from the whole plant of Centipeda minima. Minimolide L does not inhibit nitric oxide production. Minimolide L exhibits no anticancer activity against liver cancer, colorectal cancer, and cervical cancer.

For research use only. We do not sell to patients.

Minimolide L

Minimolide L Chemical Structure

CAS No. : 2629213-38-1

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Minimolide L Related Antibodies

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Description

Minimolide L is a sesquiterpene lactone. Minimolide L can be isolated from the whole plant of Centipeda minima. Minimolide L does not inhibit nitric oxide production. Minimolide L exhibits no anticancer activity against liver cancer, colorectal cancer, and cervical cancer[1].

In Vitro

Minimolide L (0.19-40 μM; 48 h) is inactive against Hela, HCT-116, and HepG2 cells, with an IC50 >10 μM for all tested cell lines[1].
Minimolide L (0.066-50 μM; 24 h) is inactive against nitric oxide production in lipopolysaccharide-activated RAW 264.7 cells, with an IC50 >10 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Minimolide L Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: Hela human cervical carcinoma cells, HCT-116 human colon carcinoma cells, HepG2 human liver hepatocellular carcinoma cells
Concentration: 0.19-40 μM
Incubation Time: 48 h
Result: Exhibited no cytotoxic activity against Hela, HCT-116, and HepG2 cells, with an IC50 value greater than 10 μM for all three cell lines.
Molecular Weight

378.47

Formula

C21H30O6
CAS No.
SMILES

C[C@]12[C@@H](OC(/C(=C\C)/C)=O)[C@]3([C@@](C[C@@H](C)[C@@]1([C@H](OC)CC2=O)[H])(OC(=O)[C@H]3C)[H])[H]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Minimolide L Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Minimolide L2629213-38-1Otherspseudoguaianolide-type sesquiterpene lactoneHelaHCT-116HepG2 cellsCentipeda minimahuman cancer cellslipopolysaccharide-activated macrophagesnitric oxideRAW 264.7 cellsInhibitorinhibitorinhibit

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