Teixobactin 

Teixobactin is a potent antibiotic. Teixobactin shows antibacterial activity for gram-negative bacteria. Teixobactin inhibits cell wall synthesis by binding to a highly conserved motif of lipid II and lipid III^[1][2][3].

Teixobactin (0-128 µg/mL) shows antibacterial activity with a MIC value of 0.25 µg/mL for MRSA ATCC 33591^[2].
Teixobactin (0-24 h) shows antibacterial activity with MIC values of 5, 20 ng/mL for Clostridium difficile, Bacillus anthracis, respectively^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Teixobactin (1-20 mg/kg; i.v.; once) shows antibacterial activity in mice^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1242.47

C₅₈H₉₅N₁₅O₁₅

1613225-53-8

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Piddock LJ. Teixobactin, the first of a new class of antibiotics discovered by iChip technology? J Antimicrob Chemother. 2015 Oct;70(10):2679-80.  [Content Brief]

  [2]. Parmar A, et al. Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding. Chem Sci. 2017 Dec 1;8(12):8183-8192.  [Content Brief]

  [3]. Ling LL, et al. A new antibiotic kills pathogens without detectable resistance. Nature. 2015 Jan 22;517(7535):455-9.  [Content Brief]