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  4. Teixobactin

Teixobactin is a potent antibiotic. Teixobactin shows antibacterial activity for gram-negative bacteria. Teixobactin inhibits cell wall synthesis by binding to a highly conserved motif of lipid II and lipid III.

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Teixobactin

Teixobactin 화학구조

CAS No. : 1613225-53-8

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Teixobactin Related Antibodies

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제품 설명

Teixobactin is a potent antibiotic. Teixobactin shows antibacterial activity for gram-negative bacteria. Teixobactin inhibits cell wall synthesis by binding to a highly conserved motif of lipid II and lipid III[1][2][3].

In Vitro

Teixobactin (0-128 µg/mL) shows antibacterial activity with a MIC value of 0.25 µg/mL for MRSA ATCC 33591[2].
Teixobactin (0-24 h) shows antibacterial activity with MIC values of 5, 20 ng/mL for Clostridium difficile, Bacillus anthracis, respectively[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Teixobactin Related Antibodies
In Vivo

Teixobactin (1-20 mg/kg; i.v.; once) shows antibacterial activity in mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female CD-1 mice (MRSA ATCC33591)[3]
Dosage: 1, 2.5, 5, 10, 20 mg/kg
Administration: i.v.; once; one hour post-infection
Result: Showed good antibacterial activity and all treated animals survived.
분자량

1242.47

화학식

C58H95N15O15
CAS No.
선적

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보관

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순도&문서
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Teixobactin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Teixobactin1613225-53-8AntibioticBacterialgram-negative bacteriaantibacterialcell wallpeptidoglycanInhibitorinhibitorinhibit

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Teixobactin
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HY-P0230
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