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Results for "

4-methylumbelliferyl-

" in MedChemExpress (MCE) Product Catalog:

75

Inhibitors & Agonists

13

Fluorescent Dye

30

Biochemical Assay Reagents

14

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5

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Products

2

Isotope-Labeled Compounds

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123633

    Glycosidase Others
    4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity . 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively .
    4-Methylumbelliferyl β-D-Glucopyranoside
  • HY-D0994
    4-Methylumbelliferyl phosphate
    1 Publications Verification

    4-MUP; MUP

    Phosphatase Others
    4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .
    4-Methylumbelliferyl phosphate
  • HY-120166
    DiFMUP
    1 Publications Verification

    6,8-Difluoro-4-methylumbelliferyl phosphate

    Phosphatase Others
    DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader .
    DiFMUP
  • HY-134124

    Reactive Oxygen Species (ROS) Metabolic Disease
    Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
    Glutathione ethyl ester
  • HY-D0935A

    MUG

    β-glucuronidase Fluorescent Dye Others
    4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
    4-Methylumbelliferyl-β-D-glucuronide hydrate
  • HY-137853

    Fluorescent Dye Others
    4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase .
    4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside
  • HY-118135

    4MU-α-Gal

    Fluorescent Dye Others
    4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA .
    4-Methylumbelliferyl-α-D-galactopyranoside
  • HY-P10272

    PTG-300

    Ferroportin Others
    Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
    Rusfertide
  • HY-A0248A
    Polymyxin B1
    1 Publications Verification

    Bacterial Infection
    Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
    Polymyxin B1
  • HY-117095

    Fluorescent Dye Metabolic Disease
    4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. 4-Methylumbelliferyl oleate is cleaved by lipases, liberating 4-Methylumbelliferyl (Ex/Em=320/450 nm) .
    4-Methylumbelliferyl oleate
  • HY-137824

    4-methylumbelliferyl-β-D-xyloside

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl-β-D-xylopyranoside (4-Methylumbelliferyl-β-D-xyloside) is an enzymatically hydrolyzable β-D-xylopyranoside substrate. The enzymatic hydrolysis of 4-Methylumbelliferyl-β-D-xylopyranoside is mediated by the stereochemistry-retaining β-D-xylosidase GSXynB2 via a two-step catalytic process (xylosylation followed by dexylosidation). 4-Methylumbelliferyl-β-D-xylopyranoside serves as a substrate for the β-xylosidase of Trichoderma reesei QM 9414, and its enzymatic hydrolysis process is limited by the dexylosidation step.
    4-Methylumbelliferyl-β-D-xylopyranoside
  • HY-137873

    4-methylumbelliferyl-α-D-Glucose; 4-methylumbelliferyl-α-D-Glucoside; 4-MU-α-D-Glucopyranoside

    Fluorescent Dye Glycosidase Others
    4-Methylumbelliferyl-α-D-Glucopyranoside (4-Methylumbelliferyl-α-D-Glucose) is a fluorescent substrate for α-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU has pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), respectively. The emission wavelength of 4-Methylumbelliferyl-α-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. 4-Methylumbelliferyl-α-D-Glucopyranoside can be used as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
    4-Methylumbelliferyl-α-D-Glucopyranoside
  • HY-137855

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.
    4-Methylumbelliferyl sulfate potassium
  • HY-137333

    Fluorescent Dye Others
    4-Methylumbelliferyl β-D-cellobioside is a substrate of Cellulase (HY-B2220). 4-Methylumbelliferyl β-D-cellobioside can be hydrolyzed and produces fluorescent 4-methylumbelliferone, which can be used to study the kinetics of cellulases .
    4-Methylumbelliferyl β-D-cellobioside
  • HY-137845

    Fluorescent Dye Others
    4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer .
    4-Methylumbelliferyl β-D-galactopyranoside
  • HY-W099648

    Lipase Others
    4-Methylumbelliferyl octanoate is a octoate. 4-Methylumbelliferyl octanoate can be used as a s ubstrate of hog pancreatic lipase .
    4-Methylumbelliferyl octanoate
  • HY-135036

    Fluorescent Dye Others
    4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187) .
    4-Methylumbelliferyl butyrate
  • HY-137490

    Glycosidase Metabolic Disease
    4-Methylumbelliferyl α-L-arabinofuranoside is the glycosidase substrate .
    4-Methylumbelliferyl α-L-arabinofuranoside
  • HY-W127708

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl α-L-iduronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    4-Methylumbelliferyl α-L-iduronide
  • HY-P1108A
    Astressin 2B TFA
    1 Publications Verification

    CRFR Neurological Disease Inflammation/Immunology
    Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 [4] .
    Astressin 2B TFA
  • HY-P1108
    Astressin 2B
    1 Publications Verification

    CRFR Neurological Disease Inflammation/Immunology
    Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 [4] .
    Astressin 2B
  • HY-D1530

    Fluorescent Dye Others
    4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide is a fluorogenic substrate for detecting α-N-acetylglucosaminidase .
    4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide
  • HY-137877

    4-methylumbelliferyl acetate

    Glutathione S-transferase Others
    7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition .
    7-Acetoxy-4-methylcoumarin
  • HY-W654272

    4-MU-α-idoa 2-sulfate sodium

    Fluorescent Dye Metabolic Disease
    4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-idoa 2-sulfate) sodium is a fluorogenic substrate of iduronate-2-sulfatase (I2S). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be hydrolyzed by lysosomal enzyme α-l-iduronidase (IDUA) and release the fluorophore 4-Methylumbelliferone (HY-N0187). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be used to detect Hurler syndrome .
    4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium
  • HY-W010947

    Fluorescent Dye Inflammation/Immunology
    4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions .
    4-Methylumbelliferyl palmitate
  • HY-D0935
    4-Methylumbelliferyl-β-D-glucuronide
    1 Publications Verification

    β-glucuronidase Fluorescent Dye Others
    4-Methylumbelliferyl-β-D-glucuronide is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
    4-Methylumbelliferyl-β-D-glucuronide
  • HY-W017657

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl stearate is a biochemical reagent.
    4-Methylumbelliferyl stearate
  • HY-123000

    Biochemical Assay Reagents
    4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is a fluorogenic substrate for studying the enzymatic activity of α-galactosidase. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is used to analyze enzyme activity in various biological samples, helping scientists gain insight into the function of the enzyme in vivo. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside can also be used to screen potential compounds to inhibit or activate this enzyme.
    4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside
  • HY-W009122

    4-methylumbelliferyl-alpha-d-mannoside

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl-α-d-mannoside is a fluorescent substrate for α-D-mannosidase.
    4-Methylumbelliferyl-α-d-mannoside
  • HY-P10143

    Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt

    MMP Others
    MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .
    MMP-2/MMP-9 Substrate
  • HY-A0248AS

    Isotope-Labeled Compounds Bacterial Infection
    Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
    Polymyxin B1-d7 TFA
  • HY-W040116

    4-methylumbelliferyl N,N-diacetyl-β-D-chitobioside

    Biochemical Assay Reagents Others
    MUF-diNAG (4-Methylumbelliferyl N,N-diacetyl-β-D-chitobioside) can be used as a fluorescent substrate. MUF-diNAG is a kind of biological materials or organic compounds that are widely used in life science research .
    MUF-diNAG
  • HY-D1633A

    Fluorescent Dye Others
    4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
    4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium
  • HY-D1633

    Fluorescent Dye Metabolic Disease
    4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
    4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate
  • HY-P10563

    BHV-1100

    CD38 Cancer
    Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
    Noraramtide
  • HY-W275616

    Fluorescent Dye Others
    4-Methylumbelliferyl nonanoate is a fluorogenic substrate of esterases. 4-Methylumbelliferyl nonanoate can be hydrolyzed to 4-methylumbelliferone with bright blue fluorescence .
    4-Methylumbelliferyl nonanoate
  • HY-134163

    4-methylumbelliferyl alpha-L-arabinopyranoside

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl α-L-arabinopyranoside (4-Methylumbelliferyl alpha-L-arabinopyranoside) is a substrate for enzymes that hydrolyze arabinose-containing substrates, such as α-L-arabinopyranoside .
    4-Methylumbelliferyl α-L-arabinopyranoside
  • HY-126938

    Lipase Fluorescent Dye Others
    4-Methylumbelliferyl heptanoate is a potent fluorometric substrate of lipase .
    4-Methylumbelliferyl heptanoate
  • HY-W127556

    Biochemical Assay Reagents Others
    4-methylumbelliferyl elaidate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    4-Methylumbelliferyl elaidate
  • HY-137496

    Biochemical Assay Reagents
    4-Methylumbelliferyl β-D-mannopyranoside is a substrate that exhibits β-mannosidase activity. 4-Methylumbelliferyl β-D-mannopyranoside can be used to study β-mannosidase deficiency. The reactivity of 4-Methylumbelliferyl β-D-mannopyranoside shows different inhibitory effects on various substrates.
    4-Methylumbelliferyl β-D-mannopyranoside
  • HY-W345103

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl β-D-cellotetroside is a biochemical reagent.
    4-Methylumbelliferyl β-D-cellotetroside
  • HY-137336

    Biochemical Assay Reagents
    4-Methylumbelliferyl β-D-fucoside is a kind of biochemical reagent.
    4-Methylumbelliferyl β-D-fucoside
  • HY-W345102

    Fluorescent Dye Metabolic Disease
    4-Methylumbelliferyl β-cellotrioside, a chromogenic substrate for β-glycosidases, is a cellulose fluorescent derivative .
    4-Methylumbelliferyl β-cellotrioside
  • HY-D0994A

    4-MUP disodium; MUP disodium

    Phosphatase Others
    4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .
    4-Methylumbelliferyl phosphate disodium
  • HY-W283359

    Fluorescent Dye Others
    4-Methylumbelliferyl β-D-ribofuranoside is a fluorogenic substrate of β-ribosidase .
    4-Methylumbelliferyl β-D-ribofuranoside
  • HY-134460

    Endogenous Metabolite Others
    4-Methylumbelliferyl α-L-fucopyranoside is an α-L-fucosidase. α-L-fucosidase can enhance capacitation of porcine sperm and protect sperm from premature acrosome reaction. Compared with human liver α-L-fucosidase, 4-Methylumbelliferyl α-L-fucopyranoside has considerable hydrophobicity and isoelectric focusing properties .
    4-Methylumbelliferyl α-L-fucopyranoside
  • HY-W127706

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl α-L-iduronide sodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    4-Methylumbelliferyl α-L-iduronide sodium
  • HY-W776853

    Biochemical Assay Reagents
    4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside is a fluorogenic substrate with activity for lysozyme assays. 4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside can be used to study enzyme activity and its applications in biomedicine. 4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside exhibits high sensitivity in analyzing enzyme reactions in biological samples.
    4-Methylumbelliferyl β-D-N,N',N'',N'''-tetraacetylchitotetraoside
  • HY-137403

    Biochemical Assay Reagents Others
    4-Methylumbelliferyl β-D-N,N′,N′′-triacetylchitotrioside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    4-Methylumbelliferyl β-D-N,N′,N′′-triacetylchitotrioside
  • HY-P3066

    d(CH2)5Tyr(Et)VAVP

    Vasopressin Receptor Metabolic Disease
    SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
    SKF 100398

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