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Results for "

5-fluoro-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Apoptosis (1) Biochemical Assay Reagents (7) Cannabinoid Receptor (6) COX (1) DNA Methyltransferase (2) DNA/RNA Synthesis (9) Dopamine Receptor (1) Drug Derivative (2) Drug Intermediate (7) Drug Isomer (6) Drug Metabolite (4) E3 Ligase Ligand-Linker Conjugates (1) EAAT (1) Endogenous Metabolite (1) Endothelin Receptor (1) Fluorescent Dye (1) HIV (1) HIV Integrase (1) iGluR (1) Interleukin Related (1) Isotope-Labeled Compounds (4) Ligands for E3 Ligase (4) MMP (1) NF-κB (1) Nucleoside Antimetabolite/Analog (19) Parasite (1) Phospholipase (2) Phosphoramidites (2) Prostaglandin Receptor (1) Protease Activated Receptor (PAR) (2) Reference Standards (6) Thymidylate Synthase (4) TNF Receptor (1)
By Research Areas:	Cancer (28) Cardiovascular Disease (3) Infection (1) Inflammation/Immunology (3) Neurological Disease (17)
Click Chemistry:	Azide (2)
Oligonucleotides:	Adenosine (1) Nucleoside Analogs (15) Uridine (7) Cytosine (2) Phosphoramidites (2) Cytidine (6)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12807

FIPI 5 Publications Verification 5-fluoro-2-indolyl deschlorohalopemide	Phospholipase	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
FIPI is a phospholipase D (PLD) inhibitor with an IC₅₀ for PLD1 and PLD2 of about 25 nM. FIPI regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI can be used in cancer research. In addition, FIPI can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function .

HY-B0021

Doxifluridine 2 Publications Verification Ro 21-9738; 5-fluoro-5'-deoxyuridine; 5'-DFUR	Thymidylate Synthase	Cancer
Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .

HY-I0096

Indole-2-carboxylic acid	iGluR HIV HIV Integrase	Neurological Disease
Indole-2-carboxylic acid (I2CA) is a competitive antagonist of the glycine site of the NMDA receptor (K_i=15 μM, 5-fluoro-I2CA) and an inhibitor of HIV-1 integrase. Indole-2-carboxylic acid is selective for the glycine site of the NMDA receptor and blocks the enhancement of NMDA receptor by competitively inhibiting the binding of glycine to the NMDA receptor. Indole-2-carboxylic acid can also inhibit the strand transfer activity of HIV-1 integrase by chelating Mg ²⁺ at the active site of integrase and interacting with the hydrophobic cavity. Indole-2-carboxylic acid can be used in the study of neurological diseases (such as stroke, epilepsy) and HIV-1 infection .

HY-116217

5-Fluoro-2'-deoxycytidine 3 Publications Verification FdCyd; NSC-48006	DNA Methyltransferase	Cancer
5-Fluoro-2'-deoxycytidine (FdCyd), a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of thymidylate synthase inhibitor 5-fluoro-2′-dUMP. 5-Fluoro-2'-deoxycytidine can induce cell cycle arrest in tumor cells through the DNA damage response, and it has anti-tumor activity .

HY-W016819B

5-Fluoroorotic acid monohydrate 5-fluorouracil-6-carboxylic acid Monohydrate; 5-FOA; 5-fluoro OA	Thymidylate Synthase Parasite	Infection
5-Fluoroorotic acid monohydrate is the monohydrate salt form of 5-Fluoroorotic acid (HY-W016819). 5-Fluoroorotic acid monohydrate is the inhibitor for thymidylate synthase that acts as a selective agent in yeast molecular genetics. 5-Fluoroorotic acid monohydrate exhibits antimalarial activity .

HY-W009538

5'-Deoxy-5-fluorocytidine 5-fluoro-5'-deoxycytidine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Drug Metabolite	Cancer
5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .

HY-21045

5-Fluoro-L-tryptophan L-5-fluorotryptophan	EAAT	Neurological Disease
5-Fluoro-L-tryptophan is a competitive vesicular glutamate transporter (VGLUT) inhibitor. 5-Fluoro-L-tryptophan is promising for research of diseases associated with the neurotransmitter systems .

HY-W616732

5′-Fluoro-5′-deoxyadenosine 5'-FDA	Drug Derivative	Others
5′-Fluoro-5′-deoxyadenosine is an active compound.

HY-W002914

5-Fluoro-2-oxoindoline	Biochemical Assay Reagents	Others
5-Fluoro-2-oxoindoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-155878

5-Fluoro-2′-deoxy-UTP	Biochemical Assay Reagents DNA/RNA Synthesis	Others
5-Fluoro-2′-deoxy-UTP can be used as a substrate for DNA synthesis .

HY-W007331

5-Fluorosalicylaldehyde	Biochemical Assay Reagents	Others
5-Fluoro-2-hydroxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-32924

5-Fluoro-2-methoxyphenylboronic acid	Biochemical Assay Reagents	Others
5-Fluoro-2-methoxyphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W010023

2-Amino-3-bromo-5-fluoropyridine 3-Bromo-5-fluoro-2-pyridinamine	Drug Intermediate	Others
2-Amino-3-bromo-5-fluoropyridine (3-Bromo-5-fluoro-2-pyridinamine) is a drug intermediate that can be used for the synthesis fluorinated pyridines .

HY-P2496

*Endothelin 1 (swine, human), Alexa Fluor* 488-labeled**	Endothelin Receptor Fluorescent Dye NF-κB COX Prostaglandin Receptor Apoptosis TNF Receptor Interleukin Related MMP	Cardiovascular Disease Inflammation/Immunology Cancer
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is an Endothelin-1 conjugated with Alexa Fluor 488 (HY-D1304). Endothelin-1 is an endogenous vasoconstrictor and agonist of ETA/ETB receptor. Endothelin 1 (swine, human) exerts effects including promoting mitosis, angiogenesis, tumor invasion and metastasis, and inhibiting apoptosis. Endothelin 1 (swine, human) induces inflammation and oxidative stress by activating the NF-κB pathway. Endothelin 1 (swine, human), Alexa Fluor 488-labeled is specifically designed for fluorescence imaging, flow cytometry or receptor localization studies, and can be used in research related to sepsis, atherosclerosis, systemic inflammatory response syndrome, cancer and congestive heart failure .

HY-P5372A

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-44532

5-Fluoro-2-hydroxynicotinaldehyde	Drug Intermediate	Others
5-Fluoro-2-hydroxynicotinaldehyde is a drug intermediate for synthesis of various active compounds.

HY-23660

5-Fluoro-2-(1H-pyrrol-1-yl)aniline	Drug Intermediate	Others
5-Fluoro-2-(1H-pyrrol-1-yl)aniline is a drug intermediate for synthesis of various active compounds.

HY-43489

5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl acetate	Drug Intermediate	Others
5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl acetate is a drug intermediate for synthesis of various active compounds.

HY-W009538R

5'-Deoxy-5-fluorocytidine (Standard) 5-fluoro-5'-deoxycytidine (Standard)	Nucleoside Antimetabolite/Analog Reference Standards DNA/RNA Synthesis Drug Metabolite	Cancer
5'-Deoxy-5-fluorocytidine (Standard) is the analytical standard of 5'-Deoxy-5-fluorocytidine (HY-W009538). This product is intended for research and analytical applications. 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .

HY-172058

5-Fluoro THJ	Cannabinoid Receptor	Neurological Disease
5-Fluoro THJ is a derivative of THJ-018. THJ-018 is a synthetic cannabinoid .

HY-172048

5-Fluoro PB-22 6-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 6-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172047

5-Fluoro PB-22 5-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 5-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172049

5-Fluoro PB-22 7-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 7-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172036

5-Fluoro PB-22 6-hydroxyquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-172044

5-Fluoro PB-22 N-(3-fluoropentyl) isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-172045

5-Fluoro PB-22 N-(4-fluoropentyl) isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(4-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-172035

5-Fluoro PB-22 5-hydroxyquinoline isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 5-hydroxyquinoline isomer is a synthetic cannabinoid.

HY-W768607

5-Fluoro PB-22 8-hydroxyisoquinoline isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 8-hydroxyisoquinoline isomer is structurally similar to known synthetic cannabinoids.

HY-172043

5-Fluoro PB-22 N-(2-fluoropentyl) isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 N-(2-fluoropentyl) isomer is a derivative of cannabinoid.

HY-114553

5-Fluoro PB-22 3-carboxyindole metabolite 5F-PB-22 3-carboxyindole metabolite	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 3-carboxyindole metabolite (5F-PB-22 3-carboxyindole metabolite) is a metabolite of 5-fluoro PB-22. 5-Fluoro PB-22 is a synthetic cannabinoid .

HY-W005085

5-Fluoro-2-methoxybenzaldehyde 5-fluoro-O-Anisaldehyde	Biochemical Assay Reagents	Others
5-Fluoro-2-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-34656

5-Fluoro-2-pyridinecarbonitrile	Biochemical Assay Reagents	Others
5-Fluoro-2-pyridinecarbonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-155869

5-fluoro-dCTP 5-fluoro-2′-deoxycytidine 5′-triphosphate	DNA/RNA Synthesis	Others
5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .

HY-43553

*tert-Butyl (4-((5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl)amino)phenyl)carbamate*	Drug Intermediate	Others
tert-Butyl (4-((5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl)amino)phenyl)carbamate is a drug intermediate for synthesis of various active compounds.

HY-P5372

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-154128

1-(b-D-Xylofuranosyl)-5-fluorouracil 5-fluoro-xylo-uridine; (R)-5-fluorouridine	Nucleoside Antimetabolite/Analog	Cancer
1-(b-D-Xylofuranosyl)-5-fluorouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-172037

5-Fluoro PB-22 7-hydroxyquinoline isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 7-hydroxyquinoline isomer is a synthetic cannabinoid.

HY-W741747

Paliperidone impurity 4 5-fluoro paliperidone	Drug Intermediate	Others
Paliperidone impurity 4 (5-Fluoro paliperidone) is an impurity of Paliperidone.

HY-W034041

Ir(p-F-ppy)3 Tris(2-(4-fluorophenyl)pyridine)iridium; Tris[5-fluoro-2-(2-pyridinyl-kN)phenyl-kC]iridium(III)	Endogenous Metabolite
Ir(pF-ppy)3 (Tris(2-(4-fluorophenyl)pyridine)iridium) is a compound that catalyzes photoreactions and has excellent photocatalytic activity. Ir(pF-ppy)3 can be used as a catalyst in organic reactions, especially in photocatalytic synthesis. Ir(pF-ppy)3 shows its unique advantages in promoting electron transfer and improving reaction selectivity. Ir(pF-ppy)3 is also used to improve the efficiency of displays and solar cells.

HY-160428

*DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite*	Nucleoside Antimetabolite/Analog Phosphoramidites	Others
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite (compound 1B) is a phosphoramidite of 5-Fluoro-2'-deoxycytidine .

HY-116217R

5-Fluoro-2'-deoxycytidine (Standard) FdCyd (Standard); NSC-48006 (Standard)	DNA Methyltransferase Reference Standards	Cancer
5-Fluoro-2'-deoxycytidine (Standard) is the analytical standard of 5-Fluoro-2'-deoxycytidine. This product is intended for research and analytical applications. 5-Fluoro-2'-deoxycytidine (FdCyd), a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of thymidylate synthase inhibitor 5-fluoro-2′-dUMP. 5-Fluoro-2'-deoxycytidine can induce cell cycle arrest in tumor cells through the DNA damage response, and it has anti-tumor activity .

HY-23946

5-Fluoro-2-methylpyridin-3-amine	Drug Intermediate	Others
5-Fluoro-2-methylpyridin-3-amine is a drug intermediate for synthesis of various active compounds.

HY-152298

5-Fluoro-4’-thiouridine	Nucleoside Antimetabolite/Analog	Others
5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-163210

*Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride*	Ligands for E3 Ligase	Cancer
Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride (ZJT1) is an E3 ubiquitin ligase cereblon based on Pomalidomide (HY-10984) (CRBN) ligand for recruitment of cereblon protein. Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride can be linked to protein ligand by linker to form PROTAC .

HY-152522

5-Fluoro-4’-C-methyluridine	Nucleoside Antimetabolite/Analog	Others
5-Fluoro-4’-C-methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-152526

5-Fluoro-4’-C-methylcytidine	Nucleoside Antimetabolite/Analog	Others
5-Fluoro-4’-C-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .

HY-155878A

5-Fluoro-2′-deoxy-UTP sodium (100 mM in water) 1 Publications Verification	Biochemical Assay Reagents DNA/RNA Synthesis	Others
5-Fluoro-2′-deoxy-UTP sodium can be used as a substrate for DNA synthesis .

HY-152640

5-Fluoro-4’-thio-cytidine	Nucleoside Antimetabolite/Analog	Cancer
5-Fluoro-4’-thio-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W681014

5-Fluoro-α-methyltryptamine hydrochloride	5-HT Receptor Dopamine Receptor	Neurological Disease
5-Fluoro-α-methyltryptamine hydrochloride may cause an increase in intracellular levels of 5-HT followed by an increase in 5-HT release. 5-Fluoro-α-methyltryptamine hydrochloride exhibits EC₅₀ values of 37 nM, 14 nM, 78 nM and 8.47 nM for DA, *5HT, NE and 5-HT2A*, respectively .

HY-155869A

5-fluoro-dCTP sodium 5-fluoro-2′-deoxycytidine 5′-triphosphate sodium	DNA/RNA Synthesis	Others
5-fluoro-dCTP sodium is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .

Cat. No.	Product Name	Target	Research Area

HY-P2496

*Endothelin 1 (swine, human), Alexa Fluor* 488-labeled**	Endothelin Receptor Fluorescent Dye NF-κB COX Prostaglandin Receptor Apoptosis TNF Receptor Interleukin Related MMP	Cardiovascular Disease Inflammation/Immunology Cancer
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is an Endothelin-1 conjugated with Alexa Fluor 488 (HY-D1304). Endothelin-1 is an endogenous vasoconstrictor and agonist of ETA/ETB receptor. Endothelin 1 (swine, human) exerts effects including promoting mitosis, angiogenesis, tumor invasion and metastasis, and inhibiting apoptosis. Endothelin 1 (swine, human) induces inflammation and oxidative stress by activating the NF-κB pathway. Endothelin 1 (swine, human), Alexa Fluor 488-labeled is specifically designed for fluorescence imaging, flow cytometry or receptor localization studies, and can be used in research related to sepsis, atherosclerosis, systemic inflammatory response syndrome, cancer and congestive heart failure .

HY-P5372A

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-P5373

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2	Peptides	Others
Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)

HY-P5372

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-I0096

Indole-2-carboxylic acid	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	iGluR HIV HIV Integrase
Indole-2-carboxylic acid (I2CA) is a competitive antagonist of the glycine site of the NMDA receptor (K_i=15 μM, 5-fluoro-I2CA) and an inhibitor of HIV-1 integrase. Indole-2-carboxylic acid is selective for the glycine site of the NMDA receptor and blocks the enhancement of NMDA receptor by competitively inhibiting the binding of glycine to the NMDA receptor. Indole-2-carboxylic acid can also inhibit the strand transfer activity of HIV-1 integrase by chelating Mg ²⁺ at the active site of integrase and interacting with the hydrophobic cavity. Indole-2-carboxylic acid can be used in the study of neurological diseases (such as stroke, epilepsy) and HIV-1 infection .

Cat. No.	Product Name	Chemical Structure

HY-W009538S

5'-Deoxy-5-fluorocytidine-d3

5'-Deoxy-5-fluorocytidine-d₃ is deuterated labeled 5'-Deoxy-5-fluorocytidine (HY-W009538). 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .

HY-W009538S1

5'-Deoxy-5-fluorocytidine-13C5

5'-Deoxy-5-fluorocytidine-13C5 is the ¹³C labeled isotope of 5'-Deoxy-5-fluorocytidine (HY-W009538). 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .

HY-B0021S1

Doxifluridine-d3
Doxifluridine-d₃ is deuterated labeled Doxifluridine (HY-B0021). Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .

HY-B0021S

Doxifluridine-d2
Doxifluridine-d₂ is the deuterium labeled Doxifluridine . Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC₅₀ of 0.62 μM.

HY-W704668

*4-Fluoro-2-(methoxy-d3)-1-nitrobenzene*
4-Fluoro-2-(methoxy-d₃)-1-nitrobenzene is the deuterium labeled 5-Fluoro-2-nitroanisole (HY-Y0205).

Cat. No.	Product Name		Classification

HY-152585

*3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine*		Azide
3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152597

*3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine*		Azide
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-W009538

5'-Deoxy-5-fluorocytidine 5-fluoro-5'-deoxycytidine		Nucleoside Analogs Cytidine
5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .

HY-W616732

5′-Fluoro-5′-deoxyadenosine 5'-FDA		Nucleoside Analogs Adenosine
5′-Fluoro-5′-deoxyadenosine is an active compound.

HY-154128

1-(b-D-Xylofuranosyl)-5-fluorouracil 5-fluoro-xylo-uridine; (R)-5-fluorouridine		Nucleoside Analogs Uridine
1-(b-D-Xylofuranosyl)-5-fluorouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-160428

*DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite*		Phosphoramidites Cytosine
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite (compound 1B) is a phosphoramidite of 5-Fluoro-2'-deoxycytidine .

HY-152298

5-Fluoro-4’-thiouridine		Nucleoside Analogs Uridine
5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152522

5-Fluoro-4’-C-methyluridine		Nucleoside Analogs Uridine
5-Fluoro-4’-C-methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-152526

5-Fluoro-4’-C-methylcytidine		Nucleoside Analogs Cytidine
5-Fluoro-4’-C-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .

HY-152640

5-Fluoro-4’-thio-cytidine		Nucleoside Analogs Cytidine
5-Fluoro-4’-thio-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154136

5-Fluoro-3’-beta-C-methyluridine		Nucleoside Analogs Uridine
5-Fluoro-3’-beta-C-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-134554

*5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine*		Nucleoside Analogs Cytidine
5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is an impurity in the synthesis of Capecitabine (HY-B0016) .

HY-152340

*2’-Amino-2’-deoxy-5-fluoro-arabinouridine*		Nucleoside Analogs Uridine
2’-Amino-2’-deoxy-5-fluoro-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152585

*3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine*		Nucleoside Analogs Uridine
3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152597

*3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine*		Nucleoside Analogs Cytidine
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154779

*5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine*		Nucleoside Analogs Cytidine
5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152987

*7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine*		Nucleoside Analogs
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154555

*5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine*		Nucleoside Analogs Uridine
5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-204951

5'-O-DMT-2'-OMe-5-F-4-S-CE-U-3'-CE Phosphoramidite		Phosphoramidites Cytosine
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-((2-cyanoethyl)thio)-5-fluoro-2-oxopyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

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