Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.
For research use only. We do not sell to patients.
- CAS No.: 211190-38-4
- Formula: C42H63FN12O8
- Molecular Weight:883.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PAR1 |
Chemical Information
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CAS No. 211190-38-4
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Molecular Weight 883.02
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Formula C42H63FN12O8
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Sequence
Ala-{Phe(p-Fluoro)}-Arg-{Cha}-{Cit}-Tyr-NH2
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Sequence Shortening
A-{Phe(p-Fluoro)}-R-{Cha}-{Cit}-Y-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)