1. Membrane Transporter/Ion Channel
  2. Potassium Channel

Acacetin (Synonyms: 5,7-Dihydroxy-4'-methoxyflavone)

Cat. No.: HY-N0451 Purity: 98.43%
Data Sheet SDS Handling Instructions

1) Natural acacetin was a 4.0-fold and 5.5-fold more potent inhibitor of BACE-1 than oleanolic acid and maslinic acid, respectively.

For research use only. We do not sell to patients.
Acacetin Chemical Structure

Acacetin Chemical Structure

CAS No. : 480-44-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO $66 In-stock
5 mg $60 In-stock
10 mg $70 In-stock
25 mg $110 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

1) Natural acacetin was a 4.0-fold and 5.5-fold more potent inhibitor of BACE-1 than oleanolic acid and maslinic acid, respectively.[1] 2) Acacetin significantly suppressed the photoreceptor collapse. [1] 3) Acacetin significantly reduces the Aβ levels by interfering with human APP proteolytic processing and BACE-1 expression. [1] 4) Acacetin inhibited the generation of the APP-CTF by affecting APP cleavage. [1] 5) Acacetin prolongs lifespan of significantly in the dose dependent manner. Acacetin (25 uM) had the greatest effect on longevity, extending mean lifespan significantly by 27.31% at 25 uM concentration

References
M.Wt

284.26

Formula

C₁₆H₁₂O₅

CAS No.

480-44-4

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 37 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Acacetin
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