2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0139S
    Flucytosine-13C,15N2
    		98.06%
    Flucytosine-13C,15N2 (NSC 103805-13C,15N2; Ro 2-9915-13C,15N2) is a 13C- and 15N-labeled Flucytosine (HY-B0139).
    Flucytosine-<sup>13</sup>C,15</sup>N<sub>2</sub>
  • HY-B0198S
    Cefaclor-d5
    Cefaclor-d5 is the deuterium labeled Cefaclor. Cefaclor is an effective antibiotic agent, and specifically binds to penicillin-binding protein 3 (PBP 3).
    Cefaclor-d<sub>5</sub>
  • HY-P11211
    D2A21
    D2A21, a cecropin peptide, demonstrates a minimum cidal concentration of 21.69 μg/mL against Chlamydia trachomatis.
    D2A21
  • HY-108486
    Herbimycin A
    		99%
    Herbimycin A, an ansamycin antibiotic, acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60v-src and p210BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro.
    Herbimycin A
  • HY-B0200S
    Cephalexin-d5
    		98.96%
    Cephalexin-d5 is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al.
    Cephalexin-d<sub>5</sub>
  • HY-B0337S1
    Sulfadimethoxine-d6
    		99.0%
    Sulfadimethoxine-d6 is the deuterium labeled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections.
    Sulfadimethoxine-d<sub>6</sub>
  • HY-B0134R
    Bestatin (Standard)
    Bestatin (Standard) is the analytical standard of Bestatin. This product is intended for research and analytical applications. Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects.
    Bestatin (Standard)
  • HY-W327808
    DL-Lanthionine
    		98.0%
    DL-Lanthionine is a distinctive amino acid and a monosulfide counterpart to cystine, playing a vital role as a component of peptide antibiotics known as lantiobiotics, which encompass well-known examples such as nisin and subtilin.
    DL-Lanthionine
  • HY-B1781R
    Sulfachloropyridazine (Standard)
    Sulfachloropyridazine (Standard) is the analytical standard of Sulfachloropyridazine. This product is intended for research and analytical applications. Sulfachloropyridazine is a broad spectrum sulfonamide that can be used against both gram-positive and gram-negative aerobic bacteria as well as Chlamydia. Sulfachloropyridazine is also considered as a common pollutant in surface and groundwater. Sulfachloropyridazine via electro-Fenton is a model for sulfonamide antibiotics that are widespread in waters.
    Sulfachloropyridazine (Standard)
  • HY-B0334AS
    Sulbactam-d5 sodium
    		99.90%
    Sulbactam-d5 (sodium) is the deuterium labeled Sulbactam sodium. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex.
    Sulbactam-d<sub>5</sub> sodium
  • HY-105049A
    Ceftaroline hydrochloride
    		98.0%
    Ceftaroline hydrochloride (T-91825 hydrochloride) is a Cephalosporin compound and the active form of TAK-599 (HY-14737). T-91825 is active against both gram-positive and gram-negative bacteria. Ceftaroline hydrochloride has antibacterial activity against MRSA, MRSE, PISP, and PRSP, with MIC90 values of 2 μg/mL, 1 μg/mL, 0.13 μg/mL, and 0.25 μg/mL, respectively.
    Ceftaroline hydrochloride
  • HY-B0905R
    Tilmicosin (Standard)
    Tilmicosin (Standard) is the analytical standard of Tilmicosin. This product is intended for research and analytical applications. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects.
    Tilmicosin (Standard)
  • HY-B0771
    Cefozopran
    Cefozopran (SCE-2787) is a potent antibiotic with broad-spectrum antibacterial activity. Cefozopran binds PBPs, induces cell wall destruction, cell elongation, filamentation, irregular septa formation, and bactericidal, bacteriolytic activity. Cefozopran reduces bacterial counts and eradicates bacteria in mouse respiratory, urinary, and thigh muscle infections. Cefozopran can be used for the research of bacterial infections.
    Cefozopran
  • HY-133695S
    Florfenicol amine-d3-1
    Florfenicol amine-d3-1 is the deuterium labeled Florfenicol amine. Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases.
    Florfenicol amine-d<sub>3</sub>-1
  • HY-B0525
    Carbenicillin
    Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue.
    Carbenicillin
  • HY-B0778R
    Milbemycin oxime (Standard)
    Milbemycin oxime (Standard) is the analytical standard of Milbemycin oxime. This product is intended for research and analytical applications. Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms.
    Milbemycin oxime (Standard)
  • HY-B0273R
    Sulfadiazine (Standard)
    Sulfadiazine (Standard) is the analytical standard of Sulfadiazine. This product is intended for research and analytical applications. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research.
    Sulfadiazine (Standard)
  • HY-B1418R
    Tazobactam (Standard)
    Tazobactam (Standard) is the analytical standard of Tazobactam. This product is intended for research and analytical applications. Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research.
    Tazobactam (Standard)
  • HY-10844S
    Pretomanid-d4
    		99.83%
    Pretomanid-d4 is the deuterium labeled Pretomanid. Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d<sub>4</sub>
  • HY-N12908
    Roridin H
    Roridin H (Verrucarin H) is an antibiotic and can be isolated from Myrothecium verrucaria.
    Roridin H
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