1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Cefozopran

Cefozopran (Synonyms: SCE-2787)

Cat. No.: HY-B0771
Handling Instructions

Cefozopran (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms.

For research use only. We do not sell to patients.

Cefozopran Chemical Structure

Cefozopran Chemical Structure

CAS No. : 113359-04-9

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Description

Cefozopran (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms[1][2].

In Vitro

Cefozopran (SCE-2787) is a fourth-generation cephalosporin that has good activity against gram-positive organisms including methicillin-susceptible staphylococci, enterococci, and viridans group streptococci; and against gram-negative organisms including hemophilus influenza. Moreover, cefozopran has comparatively good activity against enterococci and P. aeruginosa, which are refractory to other cephalosporins[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cefozopran (SCE-2787) (5-80 mg/kg; s.c.; twice a day for 5 days; four-week-old ICR male mice) is effective against acute respiratory tract infections caused by Kiebsiella pneumonia DT-S. In the model of chronic respiratory tract infection caused by K. pneumoniae 27, Cefozopran (20-80 mg/kg; s.c.; twice a day for 7 days; five-week-old CBA/J female mice) is as effective as Ceftazidime[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

515.53

Formula

C₁₉H₁₇N₉O₅S₂

CAS No.
SMILES

[O-]C(C(N1[[email protected]@]2([H])[[email protected]](NC(/C(C3=NSC(N)=N3)=N\OC)=O)C1=O)=C(CS2)C[N+]4=C(C=CC=N5)N5C=C4)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CefozopranSCE-2787SCE2787SCE 2787BacterialAntibioticantibacterialfourth-generationgram-negativegram-positiveorganismscephalosporintractrespiratorymiceInhibitorinhibitorinhibit

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Cefozopran
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HY-B0771
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