Ceftaroline hydrochloride
Based on 1 publication(s) in Google Scholar
Ceftaroline hydrochloride (T-91825 hydrochloride) is a Cephalosporin compound and the active form of TAK-599 (HY-14737). T-91825 is active against both gram-positive and gram-negative bacteria. Ceftaroline hydrochloride has antibacterial activity against MRSA, MRSE, PISP, and PRSP, with MIC90 values of 2 μg/mL, 1 μg/mL, 0.13 μg/mL, and 0.25 μg/mL, respectively.
For research use only. We do not sell to patients.
- Purity: 98.0%
- Formula: C22H21ClN8O5S4
- Molecular Weight:641.17
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Storage:
-80°C, stored under nitrogen
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Ceftaroline hydrochloride
MoreAll Antibiotic Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 641.17
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Formula C22H21ClN8O5S4
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Color Light yellow to yellow
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SMILES
C[N+]1=CC=C(C2=CSC(SC(CS[C@]3([H])[C@@H]4NC(/C(C5=NSC(N)=N5)=N\OCC)=O)=C(C([O-])=O)N3C4=O)=N2)C=C1.Cl
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Shipping
Shipping with dry ice.
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Storage
-80°C, stored under nitrogen
Publications (1)
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Journal Impact Factor
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Most Recent
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J Infect Dis
Enhanced Killing of Methicillin-Resistant Staphylococcus aureus With Ceftaroline or Vancomycin in Combination With Carbapenems. [Abstract]2025 Jul 30;232(1):181-190. PMID: 39777519
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Sader HS, et, al. Antimicrobial activity and spectrum of PPI-0903M (T-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains. Antimicrob Agents Chemother. 2005 Aug;49(8):3501-12. [Content Brief]
[2]. Iizawa Y, et, al. In vitro antimicrobial activity of T-91825, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599. J Infect Chemother. 2004 Jun;10(3):146-56. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ceftaroline hydrochloride Related Classifications
HY-105049A Related Classifications
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