1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100584S
    Davercin-13C,d3
    Davercin-13C,d3 (Erythromycin Cyclocarbonate-13C,d3) is the 13C-labeled Davercin (HY-100584). Davercin (Erythromycin Cyclocarbonate), derivative of Erythromycin, which is active against Gram-positive and some Gram-negative microorganisms.
    Davercin-<sup>13</sup>C,d<sub>3</sub>
  • HY-B0555B
    Nafcillin sodium
    Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections.
    Nafcillin sodium
  • HY-163321
    DapE-IN-1
    DapE-IN-1 (compound 3y) is a diaminopimelate desuccinylase (DapE) inhibitor and a potentially potent antibiotic.
    DapE-IN-1
  • HY-P0269A
    Magainin 1 TFA
    Magainin 1 TFA (Magainin I TFA) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 TFA exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria.
    Magainin 1 TFA
  • HY-17460AR
    Garenoxacin Mesylate hydrate (Standard)
    ACHE-IN-38 (hydrochloride) (Standard) is the analytical standard of ACHE-IN-38 (hydrochloride). This product is intended for research and analytical applications. ACHE-IN-38 hydrochloride (Compound 13b) inhibits the metabolic breakdown of the neurotransmitter acetylcholine (ACh) by the enzyme acetylcholinesterase (AChE) and hence alleviates memory deficits in patients with Alzheimer’s Disease by potentiating cholinergic transmission.
    Garenoxacin Mesylate hydrate (Standard)
  • HY-126906R
    Milbemycin A4 (Standard)
    Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activitysup>.
    Milbemycin A4 (Standard)
  • HY-N14354
    Ferrocin B
    Ferrocin B is an iron-containing cyclic decapeptide antibiotic found in the bacterium Pseudomonas fluorescens YK-310, exhibiting strong antibacterial activity primarily against Gram-negative bacteria, with particularly potent inhibitory effects on Pseudomonas aeruginosa. In a mouse infection model, Ferrocin B shows a half effective dose (ED50) of 0.593 mg/kg against P. aeruginosa. Ferrocin B holds potential for research in the field of anti-infective therapies.
    Ferrocin B
  • HY-N8386
    Berkeleylactone F
    Berkeleylactone F is an antibiotic macrolide compound. Berkeleylactone F showed modest inhibition of CCRF-CEM leukemia cells.
    Berkeleylactone F
  • HY-108290
    Riodoxol
    Riodoxol is an antiviral agent. Riodoxol affects multiplication and maturation of the virus.
    Riodoxol
  • HY-N0195R
    Azomycin (Standard)
    Azomycin (Standard) is the analytical standard of Azomycin. This product is intended for research and analytical applications. Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
    Azomycin (Standard)
  • HY-P5575
    Aurein 3.2
    Aurein 3.2 is an antibiotic antimicrobial peptide. Aurein 3.2 also has anticancer activity.
    Aurein 3.2
  • HY-NP194B
    Cyclosporin A-KLH
    Cyclosporin A-KLH is a conjugate of Cyclosporin A (HY-B0579) and KLH. Cyclosporin A is an immunosuppressant which binds to the cyclophilin .
    Cyclosporin A-KLH
  • HY-76260S
    Faropenem-d7 sodium
    Faropenem-d7 sodium is the deuterium labeled Faropenem sodium (HY-76260). Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis.
    Faropenem-d<sub>7</sub> sodium
  • HY-158289
    Isoniazid-KLH
    Isoniazid-KLH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Isoniazid-KLH
  • HY-130050
    Luzopeptin A
    Luzopeptin A (BBM-928 A) is an actinoleukin-like antitumor antibiotic. Luzopeptin A is a bifunctional DNA intercalator which can interact with isolated DNA molecules. Luzopeptin A induces an unwinding-rewinding process of the closed superhelical PM2 DNA. Luzopeptin A is active against HIV-1 and HIV-2 reverse transcriptase with IC50s of 7 nM and 68 nM for HIV-1 RT and HIV-2 RT, respectively.
    Luzopeptin A
  • HY-111134
    TAN 420C
    TAN 420C is an antibiotic that shows a strong cytotoxic activity against the lymphocytic leukemia.
    TAN 420C
  • HY-125723A
    Echinocandin B (purity>85%)
    Echinocandin B (purity>85%) (SL 7810 (purity>85%)) is a lipopeptide antifungal antibiotic. Echinocandin B (purity>85%) is produced by Aspergillus nidulans. Echinocandin B (purity>85%) inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>85%) exhibits activity against a variety of Aspergillus species.
    Echinocandin B (purity>85%)
  • HY-138083
    Parvodicin C2
    Parvodicin C2 is a glycopeptide antibiotic that can be isolated from parvosata. Parvodicin C2 has antibacterial activity.
    Parvodicin C2
  • HY-P2313
    Human β-defensin-2
    Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus. Human β-defensin-2 can be used for the study of colitis.
    Human β-defensin-2
  • HY-16770
    Sarecycline
    Sarecycline is an orally effective narrow-spectrum tetracycline derivative antibiotic. Sarecycline has anti-inflammatory activity. Sarecycline inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline can be used to study moderate to severe acne.
    Sarecycline

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