Nafcillin sodium
Based on 2 publication(s) in Google Scholar
Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections.
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- No. CAS: 985-16-0
- Fòrmula: C21H21N2NaO5S
- Peso molecular:436.46
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Nafcillin sodium
MoreVer todos los productos específicos de isoformas Beta-lactamase
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Actividad biológica
Descripciòn
IC50 & Target
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β-lactam |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:CD-1 female mice (20-25 g), with MRSA- and MSSA-infected[3]
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Dosage:100 mg/kg
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Administration:Subcutaneous injection
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Result:Protected 100% of the healthy mice with MSSA infections.
Chemical Information
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No. CAS 985-16-0
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Peso molecular 436.46
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Fòrmula C21H21N2NaO5S
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SMILES
O=C([C@@H]1N(C2=O)[C@]([C@@H]2NC(C(C3=CC=CC=C3C=C4)=C4OCC)=O)([H])SC1(C)C)O[Na]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Biomed Res Int
In Vitro Activity of β-Lactams in Combination with β-Lactamase Inhibitors against Mycobacterium tuberculosis Clinical Isolates. [Abstract]2018 Jul 2:2018:3579832. PMID: 30065936 -
Pureza y Documentación
Referencias
[1]. Tan AK, et, al. Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta-lactamase. Biochem J. 1992 Jan 1;281 ( Pt 1)(Pt 1):191-6. [Content Brief]
[2]. Palmer DL, et, al. Bacterial wound colonization after broad-spectrum versus narrow-spectrum antibiotics. Ann Thorac Surg. 1995 Mar;59(3):626-31. [Content Brief]
[3]. Lawrence I. Mortin, et al. Rapid Bactericidal Activity of Daptomycin against Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Peritonitis in Mice as Measured with Bioluminescent Bacteria. Antimicrob Agents Chemother. 2007 May; 51(5): 1787-1794. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nafcillin sodium Related Classifications
HY-B0555B Related Classifications
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