1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Nafcillin sodium monohydrate

Nafcillin sodium monohydrate 

Cat. No.: HY-B0555A Purity: 96.62%
COA Handling Instructions

Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections.

For research use only. We do not sell to patients.

Nafcillin sodium monohydrate Chemical Structure

Nafcillin sodium monohydrate Chemical Structure

CAS No. : 7177-50-6

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Estimated Time of Arrival: December 31
500 mg USD 100 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Nafcillin sodium monohydrate:

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Nafcillin sodium monohydrate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections[1][2].

IC50 & Target

Bacteria[1]

In Vivo

Nafcillin sodium monohydrate (100 mg/kg; s.c.) exhibits bactericidal activity against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA), with MICs of 0.5 μg/mL and 64.0 μg/mL for S. aureus strains Xen-29 and Xen-1, respectively, in mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CD-1 female mice (20-25 g), with MRSA- and MSSA-infected[3]
Dosage: 100 mg/kg
Administration: Subcutaneous injection
Result: Protected 100% of the healthy mice with MSSA infections.
Clinical Trial
Molecular Weight

454.47

Formula

C21H23N2NaO6S

CAS No.
SMILES

O=C([[email protected]@H]1N(C2=O)[[email protected]]([[email protected]@H]2NC(C(C3=CC=CC=C3C=C4)=C4OCC)=O)([H])SC1(C)C)O[Na].O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (220.04 mM; Need ultrasonic)

H2O : 1 mg/mL (2.20 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2004 mL 11.0018 mL 22.0037 mL
5 mM 0.4401 mL 2.2004 mL 4.4007 mL
10 mM 0.2200 mL 1.1002 mL 2.2004 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 96.62%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Nafcillin sodium monohydrate
Cat. No.:
HY-B0555A
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