1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Nafcillin sodium monohydrate

Nafcillin sodium monohydrate 

Cat. No.: HY-B0555A Purity: ≥98.0%
Handling Instructions

Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections.

For research use only. We do not sell to patients.

Nafcillin sodium monohydrate Chemical Structure

Nafcillin sodium monohydrate Chemical Structure

CAS No. : 7177-50-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g USD 72 In-stock
Estimated Time of Arrival: December 31
5 g USD 144 In-stock
Estimated Time of Arrival: December 31
10 g   Get quote  
50 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Nafcillin sodium monohydrate:

Top Publications Citing Use of Products

Publications Citing Use of MCE Nafcillin sodium monohydrate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections[1][2].

IC50 & Target

Bacteria[1]

In Vivo

Nafcillin sodium monohydrate (100 mg/kg; s.c.) exhibits bactericidal activity against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA), with MICs of 0.5 μg/mL and 64.0 μg/mL for S. aureus strains Xen-29 and Xen-1, respectively, in mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CD-1 female mice (20-25 g), with MRSA- and MSSA-infected[3]
Dosage: 100 mg/kg
Administration: Subcutaneous injection
Result: Protected 100% of the healthy mice with MSSA infections.
Clinical Trial
Molecular Weight

454.47

Formula

C₂₁H₂₃N₂NaO₆S

CAS No.
SMILES

O=C([[email protected]@H]1N(C2=O)[[email protected]]([[email protected]@H]2NC(C(C3=CC=CC=C3C=C4)=C4OCC)=O)([H])SC1(C)C)O[Na].O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (220.04 mM; Need ultrasonic)

H2O : 1 mg/mL (2.20 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2004 mL 11.0018 mL 22.0037 mL
5 mM 0.4401 mL 2.2004 mL 4.4007 mL
10 mM 0.2200 mL 1.1002 mL 2.2004 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: ≥98.0%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Nafcillin sodiumBacterialAntibioticbactericidalantibioticmethicillin-susceptiblemethicillin-resistantstaphylococcalInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Nafcillin sodium monohydrate
Cat. No.:
HY-B0555A
Quantity:
MCE Japan Authorized Agent: