1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Choline theophyllinate

Choline theophyllinate  (Synonyms: Oxtriphylline)

Cat. No.: HY-B1718 Pureza: 99.95%
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Choline theophyllinate (Oxtriphylline) is a choline salt of theophylline with anti-asthmatic activity.

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No. CAS : 4499-40-5

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
En stock
Solution
10 mM * 1 mL in Water En stock
Solid
50 mg En stock
100 mg En stock
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

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Revisión del cliente

Based on 4 publication(s) in Google Scholar

Other Forms of Choline theophyllinate:

Top Publications Citing Use of Products
Cell Proliferation/Viability Assay
Cell Migration/Invasion Assay
RT-PCR
In Vivo Efficacy Study

    Choline theophyllinate purchased from MedChemExpress. Usage Cited in: J Hazard Mater. 2025 Jun 5:489:137573.  [Abstract]

    Choline (30 μM, 24 h) demonstrated no cytotoxic effects but partially mitigated the inhibition of cell viability induced by EHDPP in HTR-8/SVneo and JEG-3 cells.

    Choline theophyllinate purchased from MedChemExpress. Usage Cited in: J Hazard Mater. 2025 Jun 5:489:137573.  [Abstract]

    Choline (30 μM, 24 h) reversed EHDPP-induced cell migration inhibition in HTR-8/SVneo cells.

    Choline theophyllinate purchased from MedChemExpress. Usage Cited in: J Hazard Mater. 2025 Jun 5:489:137573.  [Abstract]

    Choline (30 μM, 24 h) reversed the EHDPP-induced decrease of mRNA levels of TNF-α, IL-6, and IL-1β in HTR-8/SVneo cells.

    Choline theophyllinate purchased from MedChemExpress. Usage Cited in: J Hazard Mater. 2025 Jun 5:489:137573.  [Abstract]

    Choline supplementation (25 mM choline-containing water for 31.5 days) significantly increased uterine size, fetal weight, placental weight, and placental diameter that were reduced by EHDPP exposure.

    Choline theophyllinate purchased from MedChemExpress. Usage Cited in: J Hazard Mater. 2025 Jun 5:489:137573.  [Abstract]

    Choline supplementation (25 mM choline-containing water for 31.5 days) alleviated the decrease in mRNA expression of the proliferation marker Ki67 and the vascular differentiation marker CD31 induced by EHDPP.

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    Descripciòn

    Choline theophyllinate (Oxtriphylline) is a choline salt of theophylline with anti-asthmatic activity[1][2].

    IC50 & Target

    Human Endogenous Metabolite

     

    Peso molecular

    283.33

    Fòrmula

    C12H21N5O3

    No. CAS
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    C[N+](C)(CCO)C.CN1C2=C(C(N(C1=O)C)=O)N=C[N-]2

    Structure Classification
    Initial Source
    Envío

    Room temperature in continental US; may vary elsewhere.

    Almacenamiento

    4°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvente y solubilidad
    In Vitro: 

    H2O : 250 mg/mL (882.36 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.5295 mL 17.6473 mL 35.2945 mL
    5 mM 0.7059 mL 3.5295 mL 7.0589 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Calculadora de molaridad

    • Calculadora de dilución

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Pureza y Documentación
    Referencias

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 3.5295 mL 17.6473 mL 35.2945 mL 88.2363 mL
    5 mM 0.7059 mL 3.5295 mL 7.0589 mL 17.6473 mL
    10 mM 0.3529 mL 1.7647 mL 3.5295 mL 8.8236 mL
    15 mM 0.2353 mL 1.1765 mL 2.3530 mL 5.8824 mL
    20 mM 0.1765 mL 0.8824 mL 1.7647 mL 4.4118 mL
    25 mM 0.1412 mL 0.7059 mL 1.4118 mL 3.5295 mL
    30 mM 0.1176 mL 0.5882 mL 1.1765 mL 2.9412 mL
    40 mM 0.0882 mL 0.4412 mL 0.8824 mL 2.2059 mL
    50 mM 0.0706 mL 0.3529 mL 0.7059 mL 1.7647 mL
    60 mM 0.0588 mL 0.2941 mL 0.5882 mL 1.4706 mL
    80 mM 0.0441 mL 0.2206 mL 0.4412 mL 1.1030 mL
    100 mM 0.0353 mL 0.1765 mL 0.3529 mL 0.8824 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Inquiry Information

    Nombre del producto:
    Choline theophyllinate
    Cat. No.:
    HY-B1718
    Cantidad:
    MCE Japan Authorized Agent: