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Cat. No.: HY-B1718R

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Choline theophyllinate (Standard)

Name: Choline theophyllinate (Standard)
Brand: MedChemExpress
SKU: HY-B1718R
Availability: PreOrder

(Synonyms: Oxtriphylline (Standard))

Choline theophyllinate (Standard) (Oxtriphylline (Standard)) is the analytical standard of Choline theophyllinate (HY-B1718). This product is intended for research and analytical applications. Choline theophyllinate (Oxtriphylline) is an orally active methylxanthine derivative. Choline theophyllinate exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline theophyllinate relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. It modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline theophyllinate is used in studies of bronchospasm, nocturnal asthma, and chronic asthma.

For research use only. We do not sell to patients.

CAS No.: 4499-40-5
Formula: C₁₂H₂₁N₅O₃
Molecular Weight:283.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Choline theophyllinate (Standard) Chemical Structure

CAS No.: 4499-40-5

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 4499-40-5
Molecular Weight 283.33
Formula C₁₂H₂₁N₅O₃
SMILES

C[N+](C)(CCO)C.CN1C2=C(C(N(C1=O)C)=O)N=C[N-]2
Synonyms

Oxtriphylline (Standard)
Structure Classification
- Others
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. ARMITAGE AK, et al. Thioxanthines with potent brochodilator and coronary dilator properties. Br J Pharmacol Chemother. 1961 Feb;16(1):59-76.

[2]. Rhind GB, et al. Sustained release choline theophyllinate in nocturnal asthma. British medical journal (Clinical research ed.). 1985 Dec 07;291(6509):1605-7.

[3]. Hibberd SG, et al. Acute and chronic pharmacokinetics of asymmetrical doses of slow release choline theophyllinate in asthma. British journal of clinical pharmacology. 1986 Sep;22(3):337-41.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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