Choline theophyllinate (Standard)
Choline theophyllinate (Standard) (Oxtriphylline (Standard)) is the analytical standard of Choline theophyllinate (HY-B1718). This product is intended for research and analytical applications. Choline theophyllinate (Oxtriphylline) is an orally active methylxanthine derivative. Choline theophyllinate exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline theophyllinate can act on ADORA2A. Choline theophyllinate relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. It modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline theophyllinate is used in studies of bronchospasm, nocturnal asthma, and chronic asthma.
For research use only. We do not sell to patients.
- CAS No.: 4499-40-5
- Formula: C12H21N5O3
- Molecular Weight:283.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 4499-40-5
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Molecular Weight 283.33
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Formula C12H21N5O3
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SMILES
C[N+](C)(CCO)C.CN1C2=C(C(N(C1=O)C)=O)N=C[N-]2
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Synonyms
Oxtriphylline (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. ARMITAGE AK, et al. Thioxanthines with potent brochodilator and coronary dilator properties. Br J Pharmacol Chemother. 1961 Feb;16(1):59-76. [Content Brief]
[2]. Rhind GB, et al. Sustained release choline theophyllinate in nocturnal asthma. British medical journal (Clinical research ed.). 1985 Dec 07;291(6509):1605-7. [Content Brief]
[3]. Hibberd SG, et al. Acute and chronic pharmacokinetics of asymmetrical doses of slow release choline theophyllinate in asthma. British journal of clinical pharmacology. 1986 Sep;22(3):337-41. [Content Brief]
[4]. Liu Y, et al. Systematic Identification and Assessment of Therapeutic Targets for Breast Cancer Based on Genome-Wide RNA Interference Transcriptomes. Genes (Basel). 2017 Feb 24;8(3):86. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Choline theophyllinate (Standard) Related Classifications
HY-B1718R Related Classifications
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