2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. D-Ala-D-Ala

D-Ala-D-Ala  (Synonyms: D-Alanyl-D-alanine; H-D-Ala-D-Ala-OH)

Cat. No.: HY-W015450 Purity: 98.0%
COA
SDS
Handling Instructions Technical Support

D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase.

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Custom Peptide Synthesis

D-Ala-D-Ala

D-Ala-D-Ala 화학구조

CAS No. : 923-16-0

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in Water 해외재고보유
Solid
100 mg 해외재고보유
250 mg 해외재고보유
1 g 해외재고보유
5 g 해외재고보유
10 g   견적 받기  
50 g   견적 받기  

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고객리뷰

Based on 1 Customer Validation

Other Forms of D-Ala-D-Ala:

D-Ala-D-Ala Related Antibodies

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Human Endogenous Metabolite Microbial Metabolite

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase[1][2][3].

IC50 & Target

Microbial Metabolite

 

In Vitro

D-Ala-D-Ala (15 mM) shows a 30% decrease in the GRABS score for the dadA::Tn mutant[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

D-Ala-D-Ala Related Antibodies
분자량

160.17

화학식

C6H12N2O3
CAS No.
Appearance

Solid

Color

White to off-white

Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

H2O : 100 mg/mL (624.34 mM; Need ultrasonic)

DMSO : 2 mg/mL (12.49 mM; ultrasonic and adjust pH to 5 with HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.2434 mL 31.2168 mL 62.4337 mL
5 mM 1.2487 mL 6.2434 mL 12.4867 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 98.0%

SDS (393 KB)

COA (247 KB) HNMR (241 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 6.2434 mL 31.2168 mL 62.4337 mL 156.0842 mL
5 mM 1.2487 mL 6.2434 mL 12.4867 mL 31.2168 mL
10 mM 0.6243 mL 3.1217 mL 6.2434 mL 15.6084 mL
H2O 15 mM 0.4162 mL 2.0811 mL 4.1622 mL 10.4056 mL
20 mM 0.3122 mL 1.5608 mL 3.1217 mL 7.8042 mL
25 mM 0.2497 mL 1.2487 mL 2.4973 mL 6.2434 mL
30 mM 0.2081 mL 1.0406 mL 2.0811 mL 5.2028 mL
40 mM 0.1561 mL 0.7804 mL 1.5608 mL 3.9021 mL
50 mM 0.1249 mL 0.6243 mL 1.2487 mL 3.1217 mL
60 mM 0.1041 mL 0.5203 mL 1.0406 mL 2.6014 mL
80 mM 0.0780 mL 0.3902 mL 0.7804 mL 1.9511 mL
100 mM 0.0624 mL 0.3122 mL 0.6243 mL 1.5608 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-Ala-D-Ala Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-Ala-D-Ala923-16-0D-Alanyl-D-alanine H-D-Ala-D-Ala-OHEndogenous Metabolitepeptidoglycantranspeptidation reactionD-Alanine-D-Alanine ligaseInhibitorinhibitorinhibit

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상품명:
D-Ala-D-Ala
Cat. No.:
HY-W015450
수량:
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SAFETY DATA SHEET (SDS)

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