923-16-0
923-16-0
Chemical Structure
D-Ala-D-Ala
Synonym(s): D-Alanyl-D-alanine; H-D-Ala-D-Ala-OH
- CAS. Nr.: 923-16-0
- Formula:C6H12N2O3
- Molecular Weight:160.17
IUPAC Name: D-alanyl-D-alanine
InChIKey: DEFJQIDDEAULHB-QWWZWVQMSA-N
SMILES: C[C@H](C(O)=O)NC([C@@H](C)N)=O
Biological Activity: D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase[1][2][3].
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D-Ala-D-Ala | 98.0% | D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase. | ||||||||||||||||||||
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D-Ala-D-Ala (Standard) | 99.25% | D-Ala-D-Ala (Standard) is the analytical standard of D-Ala-D-Ala. This product is intended for research and analytical applications. D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase. | ||||||||||||||||||||
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References
- [1]. Kitamura Y, et al. Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1098-106. [Content Brief]
- [2]. Tytgat I, et al. DD-ligases as a potential target for antibiotics: past, present and future. Curr Med Chem. 2009;16(20):2566-80. [Content Brief]
- [3]. Trivedi RR, et al. Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness. mBio. 2018 Sep 11;9(5):e01340-18. [Content Brief]
Keywords
