Exatecan-methylacetamide-OH

Cat. No.: HY-156849 Purity: 97.30%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Exatecan-methylacetamide-OH (compound 6) is a Exatecan derivative with anticancer effects. Exatecan-methylacetamide-OH is an ADC cytotoxin that can be used to synthesize Antibody-Drug Conjugates (ADCs) (CN112125915A; compound 6).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Exatecan-methylacetamide-OH 화학구조

CAS No. : 2594423-51-3

사이즈	재고	수량
1 mg	해외재고보유	Estimated Time of Arrival: December 31
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Topoisomerase Topo I Topo II DNA gyrase

Biological Activity
순도&문서
References
고객리뷰

제품 설명

IC₅₀ & Target

Camptothecins

분자량

507.51

화학식

C₂₇H₂₆FN₃O₆

CAS No.

2594423-51-3

Appearance

Solid

Color

Light yellow to yellow

SMILES

OCC(N([C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)C)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

DMSO : 100 mg/mL (197.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9704 mL	9.8520 mL	19.7040 mL
5 mM	0.3941 mL	1.9704 mL	3.9408 mL
10 mM	0.1970 mL	0.9852 mL	1.9704 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 97.30%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (261 KB) HNMR (438 KB) RP-HPLC (261 KB) LCMS (104 KB)

Handling Instructions (2659 KB)

References

[1]. Yi Zhu, et al. Camptothecin derivative and conjugate thereof. CN112125915A.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9704 mL	9.8520 mL	19.7040 mL	49.2601 mL
	5 mM	0.3941 mL	1.9704 mL	3.9408 mL	9.8520 mL
	10 mM	0.1970 mL	0.9852 mL	1.9704 mL	4.9260 mL
	15 mM	0.1314 mL	0.6568 mL	1.3136 mL	3.2840 mL
	20 mM	0.0985 mL	0.4926 mL	0.9852 mL	2.4630 mL
	25 mM	0.0788 mL	0.3941 mL	0.7882 mL	1.9704 mL
	30 mM	0.0657 mL	0.3284 mL	0.6568 mL	1.6420 mL
	40 mM	0.0493 mL	0.2463 mL	0.4926 mL	1.2315 mL
	50 mM	0.0394 mL	0.1970 mL	0.3941 mL	0.9852 mL
	60 mM	0.0328 mL	0.1642 mL	0.3284 mL	0.8210 mL
	80 mM	0.0246 mL	0.1232 mL	0.2463 mL	0.6158 mL
	100 mM	0.0197 mL	0.0985 mL	0.1970 mL	0.4926 mL