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Results for "

methyl-2-o-

" in MedChemExpress (MCE) Product Catalog:

38

Inhibitors & Agonists

3

Biochemical Assay Reagents

14

Peptides

5

Natural
Products

3

Isotope-Labeled Compounds

19

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134124
    Glutathione ethyl ester

    		Reactive Oxygen Species (ROS) Metabolic Disease
    Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
    Glutathione ethyl ester
  • HY-P10272
    Rusfertide

    PTG-300

    		 Ferroportin Others
    Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis [2].
    Rusfertide
  • HY-A0248A
    Polymyxin B1
    1 Publications Verification

    		 Bacterial Infection
    Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment [2].
    Polymyxin B1
  • HY-P1108A
    Astressin 2B TFA
    1 Publications Verification

    		 CRFR Neurological Disease Inflammation/Immunology
    Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 [2] .
    Astressin 2B TFA
  • HY-P1108
    Astressin 2B
    1 Publications Verification

    		 CRFR Neurological Disease Inflammation/Immunology
    Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 [2] .
    Astressin 2B
  • HY-W392809
    5-Methyl-2′-O-methylcytidine

    		Nucleoside Antimetabolite/Analog Others
    5-Methyl-2′-O-methylcytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Methyl-2′-O-methylcytidine
  • HY-152358
    N3-Methyl-2’-O-methyluridine

    		Nucleoside Antimetabolite/Analog Others
    N3-Methyl-2’-O-methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
    N3-Methyl-2’-O-methyluridine
  • HY-W100234
    5-Methyl-2′-O-methyl-uridine

    2'-O-methyl-5-methyluridine

    		 Nucleoside Antimetabolite/Analog Cancer
    5-Methyl-2’-O-methyl-uridine (2'-O-methyl-5-methyluridine) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 5-Methyl-2’-O-methyl-uridine is a modified nucleoside that can be found in tRNA isolated from rabbit liver [2].
    5-Methyl-2′-O-methyl-uridine
  • HY-P10143
    MMP-2/MMP-9 Substrate

    Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt

    		 MMP Others
    MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties [2].
    MMP-2/MMP-9 Substrate
  • HY-A0248AS
    Polymyxin B1-d7 TFA

    		Isotope-Labeled Compounds Bacterial Infection
    Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment [2].
    Polymyxin B1-d7 TFA
  • HY-152693
    N4-Methyl-2’-O-methyl-cytidine
    1 Publications Verification

    		 Nucleoside Antimetabolite/Analog Others
    N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    N4-Methyl-2’-O-methyl-cytidine
  • HY-P10563
    Noraramtide

    BHV-1100

    		 CD38 Cancer
    Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
    Noraramtide
  • HY-152499
    1-Methyl-2'-O-methylinosine

    		Nucleoside Antimetabolite/Analog Cancer
    1-Methyl-2'-O-methylinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    1-Methyl-2'-O-methylinosine
  • HY-152547
    N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine

    		Nucleoside Antimetabolite/Analog Cancer
    N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
    N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine
  • HY-P3066
    SKF 100398

    d(CH2)5Tyr(Et)VAVP

    		 Vasopressin Receptor Metabolic Disease
    SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
    SKF 100398
  • HY-P10828
    MAPI

    		Virus Protease Infection Inflammation/Immunology
    MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
    MAPI
  • HY-W411295
    5-Methyl-2'-O,4'-C-methylenecytidine

    		Nucleoside Antimetabolite/Analog Others Cancer
    5-Methyl-2'-O,4'-C-methylenecytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
    5-Methyl-2'-O,4'-C-methylenecytidine
  • HY-152363
    N3-Methyl-2’-O-(2-methoxyethyl)uridine

    		Nucleoside Antimetabolite/Analog Others
    N3-Methyl-2’-O-(2-methoxyethyl)uridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
    N3-Methyl-2’-O-(2-methoxyethyl)uridine
  • HY-152571
    N1-Methyl-2’-O-(2-methoxyethyl) inosine

    		Nucleoside Antimetabolite/Analog Cancer
    N1-Methyl-2’-O-(2-methoxyethyl) inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    N1-Methyl-2’-O-(2-methoxyethyl) inosine
  • HY-152569
    N1-Methyl-2’-O-(2-methoxyethyl) adenosine

    		Nucleoside Antimetabolite/Analog Cancer
    N1-Methyl-2’-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    N1-Methyl-2’-O-(2-methoxyethyl) adenosine
  • HY-152570
    N6-Methyl-2’-O-(2-methoxyethyl) adenosine

    		Nucleoside Antimetabolite/Analog Cancer
    N6-Methyl-2’-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    N6-Methyl-2’-O-(2-methoxyethyl) adenosine
  • HY-152567
    N1-Methyl-2’-O-(2-methoxyethyl) guanosine

    		Nucleoside Antimetabolite/Analog Cancer
    N1-Methyl-2’-O-(2-methoxyethyl) guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    N1-Methyl-2’-O-(2-methoxyethyl) guanosine
  • HY-152568
    N7-Methyl-2’-O-(2-methoxyethyl) guanosine

    		Nucleoside Antimetabolite/Analog Cancer
    N7-Methyl-2’-O-(2-methoxyethyl) guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    N7-Methyl-2’-O-(2-methoxyethyl) guanosine
  • HY-154077
    N4-Benzoyl-5-methyl-2’-O,4’-C-methylenecytidine

    		Nucleoside Antimetabolite/Analog Cancer
    N4-Benzoyl-5-methyl-2’-O,4’-C-methylenecytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
    N4-Benzoyl-5-methyl-2’-O,4’-C-methylenecytidine
  • HY-154468
    6-O-Methyl-2’-O-methylinosine

    		Nucleoside Antimetabolite/Analog Cancer
    6-O-Methyl-2’-O-methylinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    6-O-Methyl-2’-O-methylinosine
  • HY-164767A
    N1-Methyl-2'-O-Methylpseudo-UTP

    2'-O-methylpseudouridine TP

    		 DNA/RNA Synthesis Others
    N1-Methyl-2'-O-Methylpseudo-UTP is a modified uridine triphosphate and can be used for RNA synthesis.
    N1-Methyl-2'-O-Methylpseudo-UTP
  • HY-154729
    3’-O-Methyl-2’-O-acetyl-5’-O-benzoyluridine

    		Nucleoside Antimetabolite/Analog Cancer
    3’-O-Methyl-2’-O-acetyl-5’-O-benzoyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3’-O-Methyl-2’-O-acetyl-5’-O-benzoyluridine
  • HY-152660
    2-Amino-6-O-methyl-2’-O-methyl purine riboside

    		Nucleoside Antimetabolite/Analog Cancer
    2-Amino-6-O-methyl-2’-O-methyl purine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2-Amino-6-O-methyl-2’-O-methyl purine riboside
  • HY-W777374
    Methyl 2-O-methyl-3,4-O-(1-methylethylidene)-α-D-galactopyranoside

    		Biochemical Assay Reagents Others
    Dodecyldimethylphosphine oxide is a biochemical assay reagent.
    Methyl 2-O-methyl-3,4-O-(1-methylethylidene)-α-D-galactopyranoside
  • HY-W357141
    Methyl 2-O-β-D-glucopyranosylbenzoate

    methyl salicylate 2-O-β-D-glucopyranoside

    		 Drug Derivative Inflammation/Immunology
    Methyl 2-O-β-D-glucopyranosylbenzoate (Methyl salicylate 2-O-β-D-glucopyranoside) (Compound 11) is a phenolic compound. Methyl 2-O-β-D-glucopyranosylbenzoate can be isolated from the leaves of Metapanax delavayi. Methyl 2-O-β-D-glucopyranosylbenzoate has anti-benign prostatic hyperplasia activities and significantly inhibits the proliferation of BPH-1 cells. β-Phenylethyl β-D-glucoside can be used for prostatitis research .
    Methyl 2-O-β-D-glucopyranosylbenzoate
  • HY-W753153
    O-6-Methyl-2'-deoxyguanosine-d3

    		Isotope-Labeled Compounds Others
    O-6-Methyl-2'-deoxyguanosine-d3 is the deuterium labeled O-6-Methyl-2'-deoxyguanosine.
    O-6-Methyl-2'-deoxyguanosine-d3
  • HY-W698356
    Methyl 2-O-allyl-3-O-benzyl-4,6-O-benzylidene-α-D-mannopyranoside

    		Biochemical Assay Reagents Others
    Methyl 2-O-allyl-3-O-benzyl-4,6-O-benzylidene-α-D-mannopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    Methyl 2-O-allyl-3-O-benzyl-4,6-O-benzylidene-α-D-mannopyranoside
  • HY-P2592
    Ro 23-7014

    		Cholecystokinin Receptor Others
    Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .
    Ro 23-7014
  • HY-125628
    Kahalalide A

    		Endogenous Metabolite Infection
    Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .
    Kahalalide A
  • HY-W739491
    Methyl 2-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

    		Biochemical Assay Reagents Others
    Methyl 2-O-(α-D-mannopyranosyl)-α-D-mannopyranoside is a biochemical assay reagent.
    Methyl 2-O-(α-D-mannopyranosyl)-α-D-mannopyranoside
  • HY-N17785
    2-O-Methyl-L-fucose

    		Drug Derivative Others
    2-Methyl-2-O-methyl-L-fucose, a derivative of L-fucose (HY-W854443), is a natural sugar that can be found in Taxus cuspidata .
    2-O-Methyl-L-fucose
  • HY-401441
    N6-Chloroacetyl-5'-O-DMT-N1-methyl-2'-O-TBDMS-adenosine-3'-CED phosphoramidite

    		DNA/RNA Synthesis Phosphoramidites Others
    (2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-((E)-6-((2-chloroacetyl)imino)-1-methyl-1H-purin-9(6H)-yl)-2-(((4-methoxyphenyl)diphenylmethoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    N6-Chloroacetyl-5'-O-DMT-N1-methyl-2'-O-TBDMS-adenosine-3'-CED phosphoramidite
  • HY-A0248AS1
    Polymyxin B1-D-Leu-d7 TFA

    		Isotope-Labeled Compounds Bacterial Infection
    Polymyxin B1-D-Leu-d7 TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment [2].
    Polymyxin B1-D-Leu-d7 TFA

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