2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. N4-Methyl-2’-O-methyl-cytidine

N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

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N4-Methyl-2’-O-methyl-cytidine

N4-Methyl-2’-O-methyl-cytidine Chemical Structure

CAS No. : 13048-95-8

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N4-Methyl-2’-O-methyl-cytidine Related Antibodies

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Description

N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

271.27

Formula

C11H17N3O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](OC)[C@H](N2C(N=C(NC)C=C2)=O)O[C@@H]1CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 5 mg/mL (18.43 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6864 mL 18.4318 mL 36.8636 mL
5 mM 0.7373 mL 3.6864 mL 7.3727 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.6864 mL 18.4318 mL 36.8636 mL 92.1591 mL
5 mM 0.7373 mL 3.6864 mL 7.3727 mL 18.4318 mL
10 mM 0.3686 mL 1.8432 mL 3.6864 mL 9.2159 mL
15 mM 0.2458 mL 1.2288 mL 2.4576 mL 6.1439 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N4-Methyl-2’-O-methyl-cytidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N4-Methyl-2’-O-methyl-cytidine13048-95-8Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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