2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 5-Methyl-2′-O-methyl-uridine

5-Methyl-2′-O-methyl-uridine  (Synonyms: 2'-O-Methyl-5-methyluridine)

Cat. No.: HY-W100234 Pureza: 97.44%
COA
SDS
Instrucciones de manejo Technical Support

5-Methyl-2’-O-methyl-uridine (2'-O-methyl-5-methyluridine) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 5-Methyl-2’-O-methyl-uridine is a modified nucleoside that can be found in tRNA isolated from rabbit liver.

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5-Methyl-2′-O-methyl-uridine

5-Methyl-2′-O-methyl-uridine Estructura química

No. CAS : 55486-09-4

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
100 mg En stock
500 mg En stock
1 g   Obtener un presupuesto  
5 g   Obtener un presupuesto  

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Based on 1 publication(s) in Google Scholar

5-Methyl-2′-O-methyl-uridine Related Antibodies

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Descripciòn

5-Methyl-2’-O-methyl-uridine (2'-O-methyl-5-methyluridine) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 5-Methyl-2’-O-methyl-uridine is a modified nucleoside that can be found in tRNA isolated from rabbit liver[1][2].

Peso molecular

272.26

Fòrmula

C11H16N2O6
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)[C@@H](OC)[C@H](N2C(NC(C(C)=C2)=O)=O)O1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (367.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 100 mg/mL (367.30 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6730 mL 18.3648 mL 36.7296 mL
5 mM 0.7346 mL 3.6730 mL 7.3459 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: 97.44%

SDS (393 KB)

COA (253 KB) HNMR (133 KB) RP-HPLC (99 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.6730 mL 18.3648 mL 36.7296 mL 91.8240 mL
5 mM 0.7346 mL 3.6730 mL 7.3459 mL 18.3648 mL
10 mM 0.3673 mL 1.8365 mL 3.6730 mL 9.1824 mL
15 mM 0.2449 mL 1.2243 mL 2.4486 mL 6.1216 mL
20 mM 0.1836 mL 0.9182 mL 1.8365 mL 4.5912 mL
25 mM 0.1469 mL 0.7346 mL 1.4692 mL 3.6730 mL
30 mM 0.1224 mL 0.6122 mL 1.2243 mL 3.0608 mL
40 mM 0.0918 mL 0.4591 mL 0.9182 mL 2.2956 mL
50 mM 0.0735 mL 0.3673 mL 0.7346 mL 1.8365 mL
60 mM 0.0612 mL 0.3061 mL 0.6122 mL 1.5304 mL
80 mM 0.0459 mL 0.2296 mL 0.4591 mL 1.1478 mL
100 mM 0.0367 mL 0.1836 mL 0.3673 mL 0.9182 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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5-Methyl-2′-O-methyl-uridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Methyl-2′-O-methyl-uridine55486-09-42'-O-Methyl-5-methyluridineNucleoside Antimetabolite/Analoglabelingtrack DNA synthesisInhibitorinhibitorinhibit

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Nombre del producto:
5-Methyl-2′-O-methyl-uridine
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