SB-258585 hydrochloride

Cat. No.: HY-103141 Pureza: 99.72%: Ficha de datos
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SB-258585 is a high affinity ligand for the 5-HT₆ receptor. SB-258585 binds highly to a single receptor population in a human cell line that recombines 5-HT₆ receptors. SB-258585 can be used to label recombinant and natural 5-HT₆ receptor .

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SB-258585 hydrochloride Estructura química

No. CAS : 1216468-02-8

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto
200 mg	Obtener un presupuesto

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This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 Customer Validation

Other Forms of SB-258585 hydrochloride:

SB-258585 In-stock

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas 5-HT Receptor:

Ver todas las isoformas

5-HT Receptor 5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

IC₅₀ & Target

5-HT₆ Receptor

Peso molecular

523.82

Fòrmula

C₁₈H₂₃ClIN₃O₃S

No. CAS

1216468-02-8

Appearance

Solid

Color

Off-white to light brown

SMILES

O=S(C1=CC=C(I)C=C1)(NC2=CC=C(OC)C(N3CCN(C)CC3)=C2)=O.Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvente y solubilidad

In Vitro:

DMSO : 125 mg/mL (238.63 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9091 mL	9.5453 mL	19.0905 mL
5 mM	0.3818 mL	1.9091 mL	3.8181 mL
10 mM	0.1909 mL	0.9545 mL	1.9091 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.72%

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Ficha de datos (271 KB) SDS (254 KB)

COA (249 KB) HNMR (143 KB) LCMS (94 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Hirst WD, et al. Characterization of [(125)I]-SB-258585 binding to human recombinant and native 5-HT(6) receptors in rat, pig and human brain tissue. Br J Pharmacol. 2000 Aug;130(7):1597-605. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9091 mL	9.5453 mL	19.0905 mL	47.7263 mL
	5 mM	0.3818 mL	1.9091 mL	3.8181 mL	9.5453 mL
	10 mM	0.1909 mL	0.9545 mL	1.9091 mL	4.7726 mL
	15 mM	0.1273 mL	0.6364 mL	1.2727 mL	3.1818 mL
	20 mM	0.0955 mL	0.4773 mL	0.9545 mL	2.3863 mL
	25 mM	0.0764 mL	0.3818 mL	0.7636 mL	1.9091 mL
	30 mM	0.0636 mL	0.3182 mL	0.6364 mL	1.5909 mL
	40 mM	0.0477 mL	0.2386 mL	0.4773 mL	1.1932 mL
	50 mM	0.0382 mL	0.1909 mL	0.3818 mL	0.9545 mL
	60 mM	0.0318 mL	0.1591 mL	0.3182 mL	0.7954 mL
	80 mM	0.0239 mL	0.1193 mL	0.2386 mL	0.5966 mL
	100 mM	0.0191 mL	0.0955 mL	0.1909 mL	0.4773 mL