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-carotene

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35

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1

Biochemical Assay Reagents

24

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4

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0411
    β-Carotene
    2 Publications Verification

    Provitamin A; beta-carotene

    		 Environmental Pollutants Endogenous Metabolite Reactive Oxygen Species (ROS) Apoptosis Metabolic Disease Cancer
    β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .
    β-Carotene
  • HY-W009310
    9-cis-Retinal

    		Endogenous Metabolite Organoid Others
    9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II with Kds of 8 nM and 5 nM, respectively. 9-cis-Retinal expedites differentiation and maturation of rod photoreceptors in retinal organoids .
    9-cis-Retinal
  • HY-136234
    9-cis-β-Carotene

    9Z β-carotene

    		 Endogenous Metabolite Others
    9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. 9-cis-β-Carotene inhibits photoreceptor degeneration and restores retinal function in vivo. 9-cis-β-Carotene has the potential for the study of congenital stationary night blindness and fundus albipunctatus .
    9-cis-β-Carotene
  • HY-113462
    α-Carotene

    		Others Cancer
    α-Carotene, a precursor of vitamin A, is used as an anti-metastatic agent or as an adjuvant for anti-cancer agents. α-Carotene is isolated from yellow-orange and dark-green vegetables .
    α-Carotene
  • HY-N0411R
    β-Carotene (Standard)

    Provitamin A (Standard); beta-carotene (Standard)

    		 Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Metabolic Disease Cancer
    β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .
    β-Carotene (Standard)
  • HY-W041301
    (±)-Dihydroactinidiolide

    		Drug Isomer Inflammation/Immunology
    (±)-Dihydroactinidiolide is the dextrorotatory form of Dihydroactinidiolide (HY-107805). (±)-Dihydroactinidiolide has a strong, pleasant musky, tea-like and tobacco-like aroma and is mainly found in black tea, tobacco and fruits. (±)-Dihydroactinidiolide has antioxidant activity and can be derived from β-carotene.or light adaptation in Arabidopsis .
    (±)-Dihydroactinidiolide
  • HY-128792
    1,3-Dipalmitin

    1,3-Dipalmitoylglycerol; Glycerol 1,3-dipalmitate

    		 Biochemical Assay Reagents Others
    1,3-Dipalmitin (1,3-Dipalmitoylglycerol) is a diacylglycerol compound that can be found in the tuberous roots of Typhonium giganteum Engl. 1,3-Dipalmitin acts as an adsorption inhibitor for 1,3-diglycerides and β-carotene .
    1,3-Dipalmitin
  • HY-118020A
    Loliolide

    Loliolid; Digiprolactone

    		 Endogenous Metabolite Caspase PI3K Apoptosis Akt Sirtuin Reactive Oxygen Species (ROS) NF-κB MMP Neurological Disease Cancer
    Loliolide (Loliolid) is a β-carotene metabolite. Loliolide reduces caspase 3, 8, 9 expression, enhances PI3K, AKT, SIRT1, inhibits ROS, apoptosis, and blocks NF-κB p65 nuclear translocation. Loliolide protects mitochondria, reduces oxidative stress, and increases cell viability in neuroblastoma cells. Loliolide can be used for the research of UV-induced skin damage and Parkinson’s disease .
    Loliolide
  • HY-N0411S1
    β-Carotene-d8

    Provitamin A-d8; beta-carotene-d8

    		 Isotope-Labeled Compounds Others
    β-Carotene-d8 is the deuterium labeled β-Carotene (HY-N0411) .
    β-Carotene-d8
  • HY-113326
    Phytoene

    trans-Phytoene

    		 Reactive Oxygen Species (ROS) Cancer
    Phytoene (trans-Phytoene) is a carotene pigment. Phytoene is the precursor of all carotenoids. Phytoene is the predominant PT isomer in most carotenogenic organisms. Phytoene can delay the skin tumors appearance and reduce their number in mice that are induced the tumors with UV-B light. Phytoene leads to protection against oxidative stress and malignant transformation. Phytoene inhibits the proliferation of breast cancer cells .
    Phytoene
  • HY-N0411S4
    β-Carotene-13C10

    Provitamin A-13C10; beta-carotene-13C10

    		 Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Metabolic Disease Cancer
    β-Carotene- 13C10 (Provitamin A- 13C10) is the 13C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .
    β-Carotene-13C10
  • HY-131803
    3'-Azido-3'-deoxyguanosine

    		Nucleoside Antimetabolite/Analog Inflammation/Immunology
    Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    3'-Azido-3'-deoxyguanosine
  • HY-W719989
    γ-Carotene

    		Drug Intermediate Metabolic Disease
    γ-Carotene is a carotenoid found in Hippophae rhamnoides L. and peach palm fruits. γ-Carotene exhibits no significant inhibitory activity against self-activated hepatic stellate cells in vitro. γ-Carotene can be converted into retinol (Vitamin A) (HY-B1342) and can be used for the research of vitamin A deficiency [2].
    γ-Carotene
  • HY-N15681
    β-Apo-10'-carotenal

    10'-Apo-β-carotenal

    		 Drug Metabolite Others
    β-Apo-10'-carotenal is a degradation product of β,β-carotene. β-Apo-10'-carotenal can be used in flavor research .
    β-Apo-10'-carotenal
  • HY-W595136
    (rac)-α-Carotene

    		Endogenous Metabolite Cardiovascular Disease Cancer
    (rac)-α-Carotene is the racemate of α-Carotene. α-Carotene is a carotenoid and potent antioxidant. Serum α-Carotene concentrations are inversely associated with the risk of all-cause mortality, cardiovascular disease, cancer, and mortality from all causes other than cardiovascular disease and cancer .
    (rac)-α-Carotene
  • HY-W719997
    ε-Carotene

    		Biochemical Assay Reagents
    ε-Carotene is a biochemical reagent .
    ε-Carotene
  • HY-N15378
    β-Carotene-15,15'-epoxide

    		IAP Bcl-2 Family COX TNF Receptor Caspase Apoptosis Inflammation/Immunology Cancer
    β-carotene-15,15ʹ-epoxide is a XIAP antagonist with apoptosis-inducing and antitumor activity, found in the leaves of Spondias mombin. In a DMBA (HY-W011845)-induced rat model of breast cancer, β-carotene-15,15ʹ-epoxide binds to the BIR3 domain of the anti-apoptotic protein XIAP, blocking its interaction with caspase-9 and thereby promoting tumor cell apoptosis. In addition, β-carotene-15,15ʹ-epoxide significantly downregulates the expression of BCL-2, COX-2, and TNF-α in tumor tissues, reduces MDA levels, increases catalase activity, and modulates serum levels of LDH, ALP, and ALT, demonstrating strong antioxidant, anti-inflammatory, and metabolic protective effects. β-carotene-15,15ʹ-epoxide may be used in research on inflammation-related conditions and cancers such as breast cancer .
    β-Carotene-15,15'-epoxide
  • HY-W720006
    4,4'-Diapo-ω,ω-carotene-4,4'-dial

    		Drug Derivative Others
    4,4'-Diapo-ω,ω-carotene-4,4'-dial is a carotenoid pigment. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .
    4,4'-Diapo-ω,ω-carotene-4,4'-dial
  • HY-133183
    Urolignoside

    		Biochemical Assay Reagents Others
    Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .
    Urolignoside
  • HY-W750730
    β-Zeacarotene

    		Endogenous Metabolite Others
    β-Zeacarotene is a zea carotene with vitamin A activity. β-Zeacarotene can be extracted into β-Zeacarotene and β1-Zeacarotene .
    β-Zeacarotene
  • HY-W750707
    4-Hydroxyechinenone

    		Drug Metabolite Others
    4-Hydroxyechinenone is a trace carotenoid present in the carapaces of crabs. 4-Hydroxyechinenone is also an intermediate in the metabolism of β-Carotene (HY-N0411) to Astaxanthin (HY-B2163) .
    4-Hydroxyechinenone
  • HY-W041301R
    (±)-Dihydroactinidiolide (Standard)

    		Reference Standards Drug Isomer Inflammation/Immunology
    (±)-Dihydroactinidiolide (Standard) is the analytical standard of (±)-Dihydroactinidiolide (HY-W041301). This product is intended for research and analytical applications. (±)-Dihydroactinidiolide is the dextrorotatory form of Dihydroactinidiolide (HY-107805). (±)-Dihydroactinidiolide has a strong, pleasant musky, tea-like and tobacco-like aroma and is mainly found in black tea, tobacco and fruits. (±)-Dihydroactinidiolide has antioxidant activity and can be derived from β-carotene.
    (±)-Dihydroactinidiolide (Standard)
  • HY-128792S
    1,3-Dipalmitin-d6

    Glyceryl 1,3-dipalmitate-d6; 1,3-Dipalmitoyl-glycerol-d6; Glycerol 1,3-Dipalmitate-d62

    		 Isotope-Labeled Compounds Biochemical Assay Reagents Others
    1,3-Dipalmitin-d6 (1,3-Dipalmitoylglycerol-d6) is deuterium labeled 1,3-Dipalmitin (HY-128792). 1,3-Dipalmitin (1,3-Dipalmitoylglycerol) is a diacylglycerol compound that can be found in the tuberous roots of Typhonium giganteum Engl. 1,3-Dipalmitin acts as an adsorption inhibitor for 1,3-diglycerides and β-carotene .
    1,3-Dipalmitin-d6
  • HY-W700062
    β-Cyclocitral-d5

    		Isotope-Labeled Compounds Others
    β-Cyclocitral-d5 is the deuterium labeled β-Cyclocitral (HY-W010231). β-Cyclocitral, a volatile oxidized derivative of β-carotene, is a grazer defence signal unique to the Cyanobacterium Microcystis. β-Cyclocitral, one of the predominant volatile terpenoid compounds, can upregulate the expression of defence genes to enhance excess light (EL) acclimation. β-Cyclocitral is a powerful repellent .
    β-Cyclocitral-d5
  • HY-N15682
    13-cis-β-Carotene

    (7Z)-Provitamin A; (7Z)-beta-carotene

    		 Drug Isomer Inflammation/Immunology
    13-cis-β-Carotene ((7Z)-Provitamin A; (7Z)-beta-Carotene) is a provitamin A carotenoid isomer found in leaves, flowers, stems, and fruit of Momordica charantia. 13-cis-β-Carotene undergoes nonenzymatic isomerization to other β-carotene isomers during aerobic incubation, extraction, and analysis. 13-cis-β-Carotene can be used for the research of chronic diseases .
    13-cis-β-Carotene
  • HY-E71348
    ζ-Carotene isomerase

    		Biochemical Assay Reagents Others
    ζ-Carotene isomerase (EC 5.2.1.12) catalyses the cis-trans isomerization of the 15-15' carbon-carbon double bond in 9,15,9'-tricis-ζ-Carotene, which is required for biosynthesis of all plant carotenoids. Requires heme b.
    ζ-Carotene isomerase
  • HY-W750682
    β-Carotene 5,6-epoxide

    		Drug Derivative Others
    β-Carotene 5,6-epoxide, a carotenoid, is a degradation product of β-carotene. β-Carotene 5,6-epoxide can be found in isolated chloroplasts. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .
    β-Carotene 5,6-epoxide
  • HY-E71278
    β-Carotene 15,15'-dioxygenase

    		Biochemical Assay Reagents Others
    β-Carotene 15,15'-dioxygenase (EC 1.13.11.63) requires Fe2+. The enzyme cleaves β-Carotene symmetrically, producing two molecules of all-trans-retinal. Both atoms of the oxygen molecule are incorporated into the products. The enzyme can also process β-cryptoxanthin, 8'-apo-β-carotenal, 4'-apo-β-carotenal, α-carotene and γ-carotene in decreasing order. The presence of at least one unsubstituted β-ionone ring in a substrate greater than C30 is mandatory.
    β-Carotene 15,15'-dioxygenase
  • HY-E71280
    β-Carotene isomerase

    		Biochemical Assay Reagents Others
    β-Carotene isomerase (EC 5.2.1.14) participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza.
    β-Carotene isomerase
  • HY-E71279
    β-Carotene 3-hydroxylase

    		Biochemical Assay Reagents Others
    β-Carotene 3-hydroxylase (EC 1.14.13.129) requires ferredoxin and Fe (II) . Also acts on other carotenoids with a β-end group.
    β-Carotene 3-hydroxylase
  • HY-N18696
    Papaya extract

    		Others Inflammation/Immunology
    Papaya extract contains a variety of bioactive compounds, including papain (an enzyme), flavonoids, carotenoids (such as beta-carotene), and vitamin C. Papaya extract helps break down proteins and improves overall digestive function.
    Papaya extract
  • HY-122301
    Sarcinaxanthin

    		Drug Derivative Inflammation/Immunology
    Sarcinaxanthin is a carotenoid present in various bacteria with antioxidant activity. Sarcinaxanthin scavenges singlet oxygen, thereby inhibiting oxidative degradation in the β-carotene/linoleic acid system. Sarcinaxanthin acts as a photoprotective agent against UVB radiation that induces erythema. Sarcinaxanthin can be applied in studies related to antioxidation and radiation resistance .
    Sarcinaxanthin
  • HY-N15679
    Anhydrolutein I

    Deoxylutein II; (3R,6'R)-3-Hydroxy-3',4'-didehydro-β,γ-carotene

    		 Drug Derivative Others
    Anhydrolutein I is a dehydration product of Lutein (HY-N6947). Anhydrolutein I can be isolated from the extract of steam-cooked sorrel .
    Anhydrolutein I
  • HY-128792R
    1,3-Dipalmitin (Standard)

    1,3-Dipalmitoylglycerol (Standard); Glycerol 1,3-dipalmitate (Standard)

    		 Reference Standards Biochemical Assay Reagents Others
    1,3-Dipalmitin (1,3-Dipalmitoylglycer) Standard is the analytical standard of 1,3-Dipalmitin (HY-128792). This product is intended for research and analytical applications. 1,3-Dipalmitin (1,3-Dipalmitoylglycerol) is a diacylglycerol compound that can be found in the tuberous roots of Typhonium giganteum Engl. 1,3-Dipalmitin acts as an adsorption inhibitor for 1,3-diglycerides and β-carotene.
    1,3-Dipalmitin (Standard)
  • HY-N11846
    4′-O-Methylglabridin

    		Apoptosis Caspase Inflammation/Immunology Cancer
    4′-O-Methylglabridin is an apoptosis inducer with antioxidant, cell cycle-disrupting and anticancer cytotoxic activities. 4′-O-Methylglabridin inhibits various cancer cell lines including liver cancer, breast cancer and colorectal cancer cell lines. By reducing the expression levels of phosphorylated Rb (Ser807/811) and p21 proteins, 4′-O-Methylglabridin promotes cell accumulation at the subG1 and G2/M phases, and triggers caspase-dependent apoptosis via cytochrome C release and caspase-9 activation. 4′-O-Methylglabridin also exerts antioxidant effects by inhibiting lipid peroxide levels and reducing β-carotene consumption, thereby blocking LDL oxidation. 4′-O-Methylglabridin can be used in the research of various cancers and atherosclerotic diseases .
    4′-O-Methylglabridin

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