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β-Carotene 15,15'-dioxygenase

β-Carotene 15,15'-dioxygenase (EC 1.13.11.63) requires Fe2+. The enzyme cleaves β-Carotene symmetrically, producing two molecules of all-trans-retinal. Both atoms of the oxygen molecule are incorporated into the products. The enzyme can also process β-cryptoxanthin, 8'-apo-β-carotenal, 4'-apo-β-carotenal, α-carotene and γ-carotene in decreasing order. The presence of at least one unsubstituted β-ionone ring in a substrate greater than C30 is mandatory.

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  • β-Carotene 15,15'-dioxygenase Chemical Structure
    β-Carotene 15,15'-dioxygenase Chemical Structure
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  • β-Carotene 15,15'-dioxygenase