Search Result
Results for "
4,4'-Bi-4H-1,2,4-triazole
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
7
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-B0101
-
|
UK-49858
|
Environmental Pollutants
Antibiotic
Fungal
Bacterial
|
Infection
Cancer
|
|
Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514
-
|
R51211
|
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-76200
-
|
UK-109496
|
Fungal
Bacterial
|
Infection
Neurological Disease
Cancer
|
|
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes. Voriconazole can penetrate the blood brain barrier (BBB) .
|
-
-
- HY-17373
-
-
-
- HY-14273
-
|
BAL-4815; RO-0094815
|
Fungal
Cytochrome P450
Antibiotic
|
Infection
Cancer
|
|
Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.
|
-
-
- HY-Y0219
-
|
s-triazole; Pyrrodiazole
|
Biochemical Assay Reagents
|
Others
|
|
1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-B0847
-
-
-
- HY-174304
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide is a drug-linker conjugates for ADC. Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide consists of Triptolide (HY-32735) and a stable cleavable linker (Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-Cl) (HY-174810). Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide can be used for the synthesis of antibody-drug conjugates (ADCs) .
|
-
-
- HY-117766
-
|
PC945
|
Fungal
Cytochrome P450
|
Infection
|
|
Opelconazole (PC945), a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. Opelconazole is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively .
|
-
-
- HY-Y0688S
-
-
-
- HY-W019852
-
-
-
- HY-14273S
-
|
BAL-4815-d4; RO-0094815-d4
|
Fungal
Cytochrome P450
|
Infection
|
|
Isavuconazole-d4 (BAL-4815-d4) is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi .
|
-
-
- HY-W113615
-
-
-
- HY-W012991
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-14273R
-
|
BAL-4815 (Standard); RO-0094815 (Standard)
|
Reference Standards
Fungal
Cytochrome P450
Antibiotic
|
Infection
|
|
Isavuconazole (Standard) is the analytical standard of Isavuconazole. This product is intended for research and analytical applications. Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.
|
-
-
- HY-B0101R
-
|
UK-49858 (Standard)
|
Reference Standards
Fungal
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514R
-
|
R51211 (Standard)
|
Reference Standards
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-B0847R
-
|
|
Reference Standards
Fungal
Reactive Oxygen Species (ROS)
|
Infection
|
|
Propiconazole (Standard) is the analytical standard of Propiconazole. This product is intended for research and analytical applications. Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
|
-
-
- HY-21058
-
|
|
MOFs
|
Others
|
|
3-(Pyridin-2-yl)-1,2,4-triazole is a metal-organic framework (MOF).
|
-
-
- HY-W007685
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-Y0219S1
-
-
-
- HY-Y0219A
-
|
s-triazole sodium; Pyrrodiazole sodium
|
Biochemical Assay Reagents
|
Infection
|
|
1,2,4-Triazole (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
-
- HY-WAA0156
-
|
|
Drug Intermediate
|
Others
|
|
1-(Pyrrolidin-3-yl)-1H-1,2,4-triazole oxalate is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-168005
-
|
|
p97
ATP Synthase
|
Cancer
|
|
NSC799462 is a triazole inhibitor of p97 ATPase. NSC799462 inhibits p97 ATPase activity (IC50 = 15 nM) by binding to a specific site on p97 and causing local changes in the p97 structure .
|
-
-
- HY-174810
-
|
|
ADC Linker
|
Cancer
|
|
Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-Cl is a cleavable and silyl ether-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADC) .
|
-
-
- HY-155791
-
|
|
ADC Linker
|
Cancer
|
|
SMCC-NH-CH2-triazole-PEG8-oxydiacetamide-Lys(MTT)-PAB (Page 7, Compound C) is an ADC linker that can be used for the synthesis of antibody-conjugated active molecules (ADC) .
|
-
-
- HY-76200B
-
|
UK-109496 camphorsulfonate
|
Fungal
Bacterial
|
Infection
Cancer
|
|
Voriconazole (UK-109496) camphorsulfonate is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole camphorsulfonate exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .
|
-
-
- HY-W089929
-
|
3-(2-Pyridyl)-5-(4-Pyridyl)-1,2,4-triazole
|
MOFs
|
Others
|
|
2-(3-(Pyridin-4-yl)-1H-1,2,4-triazol-5-yl)pyridine (3-(2-Pyridyl)-5-(4-Pyridyl)-1,2,4-Triazole) is a metal-organic framework (MOF).
|
-
-
- HY-17373A
-
|
SCH56592 hydrate
|
Fungal
Parasite
|
Infection
Cancer
|
|
Posaconazole hydrate is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
-
- HY-Y0219R
-
|
s-triazole (Standard); Pyrrodiazole (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
1,2,4-Triazole (Standard) is the analytical standard of 1,2,4-Triazole. This product is intended for research and analytical applications. 1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-107870
-
-
-
- HY-W331786
-
|
|
Bacterial
|
Infection
|
|
Ipconazole is a triazole fungicide that can be used for treating rice seed .
|
-
-
- HY-141941S
-
-
-
- HY-W331786R
-
|
|
Reference Standards
Bacterial
|
Infection
|
|
Ipconazole (Standard) is the analytical standard of Ipconazole. This product is intended for research and analytical applications. Ipconazole is a triazole fungicide that can be used for treating rice seed .
|
-
-
- HY-168006
-
|
|
p97
ATP Synthase
|
Cancer
|
|
NSC819701 is a triazole inhibitor of the p97 ATPase. NSC819701 inhibits the activity of p97 ATPase by binding to a specific site of p97 .
|
-
-
- HY-163789
-
|
|
ADC Linker
|
Cancer
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
-
- HY-46369
-
-
-
- HY-W586475
-
|
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Fluorescein-triazole-PEG5-DOTA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
|
-
-
- HY-W098127S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate .
|
-
-
- HY-W019852R
-
|
|
Reference Standards
Fungal
|
Infection
|
|
Flutriafol (Standard) is the analytical standard of Flutriafol. This product is intended for research and analytical applications. Flutriafol is a triazole fungicide with broad spectrum fungicidal activity.
|
-
-
- HY-B2058R
-
|
|
Reference Standards
Fungal
|
Infection
|
|
Triticonazole (Standard) is the analytical standard of Triticonazole. This product is intended for research and analytical applications. Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .
|
-
-
- HY-126677
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-agent-conjugation (ADC). Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA also is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-161812
-
|
|
Opioid Receptor
|
Others
|
|
MOR agonist-4 (2d) is a G protein signaling-biased Kappa opioid receptor (KOR) agonist with an EC50 value of 11 nM. MOR agonist-4 contains an electron withdrawing CF3 group and a bias factor of 38 based on triazole. MOR agonist-4 is used in the research of pruritis and analgesia .
|
-
-
- HY-137154
-
|
|
Drug Intermediate
|
Others
|
|
4-Azidobenzenesulfonamide (Compound 12) is a precursor for the synthesis of 1,2,3-triazoles .
|
-
-
- HY-157532
-
-
-
- HY-147711
-
|
|
Glycosidase
|
Metabolic Disease
|
|
α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent α-amylase/α-glucosidase inhibitor with IC50s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia .
|
-
-
- HY-W754459
-
|
|
Herbicide
|
Others
|
|
Triazole sulcotrione is a triazole herbicide commonly used for weed control in cornfields.
|
-
-
- HY-41749
-
|
v-triazole-4,5-dicarboxylic acid; 1,2,3-triazole-4,5-Dicarboxylicacid
|
MOFs
|
Others
|
|
1H-1,2,3-Triazole-4,5-dicarboxylic acid (v-Triazole-4,5-dicarboxylic acid) is a metal-organic framework (MOF).
|
-
-
- HY-W456472
-
|
3,5-Dipropyl-4H-{1,2,4}triazole
|
MOFs
|
Others
|
|
3,5-Dipropyl-4H-1,2,4-triazole (3,5-Dipropyl-4H-{1,2,4}triazole) is a metal-organic framework (MOF).
|
-
-
- HY-W040960R
-
|
|
Reference Standards
|
|
|
2H-1,2,4-Triazole-3-carboxamide (Standard) is the analytical standard of 2H-1,2,4-Triazole-3-carboxamide. This product is intended for research and analytical applications.
|
-
- HY-W112382
-
|
4,4'-Bi(4H-1,2,4-triazole)4-(4H-1,2,4-triazol-4-yl)-4H-1,2,4-triazole
|
MOFs
|
Others
|
|
4,4'-Bi-4H-1,2,4-triazole (4,4'-Bi(4H-1,2,4-triazole)4-(4H-1,2,4-triazol-4-yl)-4H-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W249363
-
|
3,4,5-Tris(4-bromophenyl)-1,2,4-triazole
|
MOFs
|
Others
|
|
3,4,5-Tris(4-bromophenyl)-4H-1,2,4-triazole (3,4,5-Tris(4-bromophenyl)-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-169368
-
-
- HY-W103735
-
|
|
MOFs
|
Others
|
|
3,5-Diphenyl-4H-1,2,4-triazole is a metal-organic framework (MOF).
|
-
- HY-W1049797
-
|
|
MOFs
|
Others
|
|
(4H-1,2,4-Triazole-3,5-diyl)dimethanol is a metal-organic framework (MOF).
|
-
- HY-W388902
-
|
|
MOFs
|
Others
|
|
3,5-Bis(trifluoromethyl)-4H-1,2,4-triazole is a metal-organic framework (MOF).
|
-
- HY-W075242
-
|
4-Amino-3,5-bis(3-carboxyphenyl)-4H-1,2,4-triazole
|
MOFs
|
Others
|
|
3,3'-(4-Amino-4H-1,2,4-triazole-3,5-diyl)dibenzoic acid (4-Amino-3,5-bis(3-carboxyphenyl)-4H-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W543328
-
|
|
MOFs
|
Others
|
|
3,5-Bis(2-methylphenyl)-1H-1,2,4-triazole is a metal-organic framework (MOF).
|
-
- HY-W075608
-
|
|
MOFs
|
Others
|
|
4,4'-(1H-1,2,4-Triazole-3,5-diyl)dibenzoic acid is a metal-organic framework (MOF).
|
-
- HY-W856051
-
|
|
MOFs
|
Others
|
|
2,2'-(1H-1,2,4-Triazole-3,5-diyl)dipyridine is a metal-organic framework (MOF).
|
-
- HY-W112266
-
|
|
MOFs
|
Others
|
|
5,5'-(1H-1,2,3-triazole-1,4-diyl)diisophthalic acid is a metal-organic framework (MOF).
|
-
- HY-W456459
-
|
|
MOFs
|
Others
|
|
3H,3'H-5,5'-Bibenzo[d][1,2,3]triazole is a metal-organic framework (MOF).
|
-
- HY-W112754
-
|
|
MOFs
|
Others
|
|
1,4-Bis(1H-1,2,4-triazole-1-yl)butane is a metal-organic framework (MOF).
|
-
- HY-W112861
-
|
|
MOFs
|
Others
|
|
1-(Imidazol-1-yl)-4-(1,2,4-triazole-1-yl-methyl)benzene is a metal-organic framework (MOF).
|
-
- HY-141652
-
|
|
Drug Intermediate
|
Cancer
|
|
N-2-Azidoethyl betulonamide is the building block, that could generate cytotoxic triazole derivative through click chemistry .
|
-
- HY-W456586
-
|
|
MOFs
|
Others
|
|
1-(4-Carboxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid is a metal-organic framework (MOF).
|
-
- HY-W456598
-
|
5,5',5''-((Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))triisophthalic acid
|
MOFs
|
Others
|
|
5,5',5''-(4,4',4''-(Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))triisophthalic acid (5,5',5''-((Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))triisophthalic acid) is a metal-organic framework (MOF).
|
-
- HY-W075617
-
|
|
MOFs
|
Others
|
|
4,4'-(1-Benzyl-1H-1,2,4-triazole-3,5-diyl)dipyridine is a metal-organic framework (MOF).
|
-
- HY-163107
-
|
|
Bacterial
|
Infection
|
|
Antimycobacterial agent-7 (compound 4) is a 1,2,4-triazole anti-tuberculosis agent (MIC: 2 μg/mL). Antimycobacterial agent-7 inhibits Mtb KatG and causes the accumulation of ROS in Mtb cells. ROS produces oxidative damage, leading to the death of Mtb .
|
-
- HY-W856168
-
|
|
MOFs
|
Others
|
|
4,4'-(5-Methyl-4H-1,2,4-triazole-3,4-diyl)bis[benzoic acid] is a metal-organic framework (MOF).
|
-
- HY-W249362
-
|
|
MOFs
|
Others
|
|
4,4'-(1-(Pyridin-3-ylmethyl)-1H-1,2,4-triazole-3,5-diyl)dipyridine is a metal-organic framework (MOF).
|
-
- HY-W112477
-
|
4-(4-Hydroxyphenyl)-1,2,4-triazole
|
MOFs
|
Others
|
|
4-(4H-1,2,4-Triazol-4-yl)phenol (4-(4-Hydroxyphenyl)-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W249818
-
|
5,5',5''-[1,3,5-Benzenetriyltris(1H-1,2,3-triazole-4,1-diyl)]tris-1,3-benzenedicarboxylic acid
|
MOFs
|
Others
|
|
5,5',5''-(4,4',4''-(Benzene-1,3,5-triyl)tris(1H-1,2,3-triazole-4,1-diyl))triisophthalic acid (5,5',5''-[1,3,5-Benzenetriyltris(1H-1,2,3-triazole-4,1-diyl)]tris-1,3-benzenedicarboxylic acid) is a metal-organic framework (MOF).
|
-
- HY-173582
-
|
2’-Deoxyribavirin-5’-O-triphosphate tetrasodium
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
1-β-D-2'-Deoxyribofuranosyl-1,2,4-triazole-3-carboxamide-5'-O-triphosphate (tetrasodium) is a nucleotide analog. 1-β-D-2'-Deoxyribofuranosyl-1,2,4-triazole-3-carboxamide-5'-O-triphosphate (tetrasodium) can be used in the investigation of the sequence-saturated mutagenesis (SeSaM) method .
|
-
- HY-181058
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Cyclopamine-COO-2-ethoxy-1,3-benzodioxole-O-C-Triazole-C5-AC is a drug-linker conjugate, with Cyclopamine (HY-17024) as its drug moiety. Cyclopamine-COO-2-ethoxy-1,3-benzodioxole-O-C-Triazole-C5-AC itself exhibits no significant anti-tumor activity. Cyclopamine-COO-2-ethoxy-1,3-benzodioxole-O-C-Triazole-C5-AC can be used for the synthesis of ADC molecules .
|
-
- HY-W456597
-
|
|
MOFs
|
Others
|
|
5,5'-(4,4'-(1,4-Phenylene)bis(1H-1,2,3-triazole-4,1-diyl))diisophthalic acid is a metal-organic framework (MOF).
|
-
- HY-W456596
-
|
|
MOFs
|
Others
|
|
5,5'-(4,4'-(1,3-Phenylene)bis(1H-1,2,3-triazole-4,1-diyl))diisophthalic acid is a metal-organic framework (MOF).
|
-
- HY-W112718
-
|
|
MOFs
|
Others
|
|
1,1'-(9,9-Dimethyl-9H-fluorene-2,7-diyl)bis(1H-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W090156
-
|
4H-1,2,4-triazole-4-acetic acid
|
MOFs
|
Others
|
|
2-(4H-1,2,4-Triazol-4-yl)acetic acid (4H-1,2,4-Triazole-4-acetic acid) is a metal-organic framework (MOF).
|
-
- HY-141726S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3 is the deuterium labeled rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid .
|
-
- HY-W456595
-
|
|
MOFs
|
Others
|
|
5,5'-(4,4'-(Pyridine-3,5-diyl)bis(1H-1,2,3-triazole-4,1-diyl))diisophthalic acid is a metal-organic framework (MOF).
|
-
- HY-76200C
-
|
(R,R)-UK-109496
|
Drug Isomer
|
Others
|
|
(R,R)-Voriconazole ((R,R)-UK-109496) is an enantiomer of Voriconazole (HY-76200). Voriconazole (UK-109496) is a second-generation broad-spectrum triazole antifungal compound that inhibits the biosynthesis of fungal ergosterol. Voriconazole exerts its antifungal activity by inhibiting the 14-α-lanosterol demethylation mediated by fungal cytochrome P450 enzymes. Voriconazole exhibits blood-brain barrier permeability .
|
-
- HY-W075493
-
|
1-(1,2,4-Triazol-1-ylmethyl)-1,2,4-triazole
|
MOFs
|
Others
|
|
Di(1H-1,2,4-triazol-1-yl)methane (1-(1,2,4-Triazol-1-ylmethyl)-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W075138
-
|
4,4'-(1,4-Phenylene)bis(4H-1,2,4-triazole)
|
MOFs
|
Others
|
|
1,4-Di(4H-1,2,4-triazol-4-yl)benzene (4,4'-(1,4-Phenylene)bis(4H-1,2,4-triazole)) is a metal-organic framework (MOF).
|
-
- HY-W249346
-
|
4,4'-(1,3-Phenylene)bis-4h-1,2,4-triazole
|
MOFs
|
Others
|
|
1,3-Di(4H-1,2,4-triazol-4-yl)benzene(4,4'-(1,3-Phenylene)bis-4h-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W112338
-
|
1,6-Di(1H-1,2,4-triazol-1-yl)hexane
|
MOFs
|
Others
|
|
1,1′-(1,6-Hexanediyl)bis[1H-1,2,4-triazole] (1,6-Di(1H-1,2,4-triazol-1-yl)hexane) is a metal-organic framework (MOF).
|
-
- HY-W249350
-
|
5,5'-(1,4-Phenylene)bis-1h-1,2,3-triazole
|
MOFs
|
Others
|
|
1,4-Di(1H-1,2,3-triazol-5-yl)benzene(5,5'-(1,4-Phenylene)bis-1h-1,2,3-triazole) is a metal-organic framework (MOF).
|
-
- HY-W856164
-
4,4',4'',4'''-((Ethene-1,1,2,2-tetrayltetrakis(benzene-4,1-diyl))tetrakis(1H-1,2,3-triazole-4,1-diyl))tetrabenzoic acid
|
MOFs
|
Others
|
|
4,4',4'',4'''-((Ethene-1,1,2,2-tetrayltetrakis(benzene-4,1-diyl))tetrakis(1H-1,2,3-triazole-4,1-diyl))tetrabenzoic acid is a metal-organic framework (MOF).
|
-
- HY-W021499
-
|
5-Methyl-3-(pyridin-2-yl)-1H-1,2,4-triazole
|
MOFs
|
Others
|
|
2-(3-Methyl-1H-1,2,4-triazol-5-yl)pyridine (5-Methyl-3-(pyridin-2-yl)-1H-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W075135
-
|
1-[4-(1,2,4-Triazol-1-yl)phenyl]-1,2,4-triazole
|
MOFs
|
Others
|
|
1,4-Di(1H-1,2,4-triazol-1-yl)benzene(1-[4-(1,2,4-Triazol-1-yl)phenyl]-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W075324
-
|
4,4-(4-Amino-1,2,4-triazol-3,5-diyl)dibenzoic acid
|
MOFs
|
Others
|
|
4,4'-(4-Amino-4H-1,2,4-triazole-3,5-diyl)dibenzoic acid(4,4-(4-Amino-1,2,4-triazol-3,5-diyl)dibenzoic acid) is a metal-organic framework (MOF).
|
-
- HY-W112372
-
|
1,1'-(4,4'-Biphenyldiyl)bis(1H-1,2,4-triazole)
|
MOFs
|
Others
|
|
4,4'-Di(1H-1,2,4-triazol-1-yl)-1,1'-biphenyl(1,1'-(4,4'-Biphenyldiyl)bis(1H-1,2,4-triazole)) is a metal-organic framework (MOF).
|
-
- HY-W727488
-
|
1,2,4-triazole-1-acetic acid-d4
|
Isotope-Labeled Compounds
|
Others
|
|
2-(1H-1,2,4-Triazol-1-yl)acetic acid-d4 (1,2,4-Triazole-1-acetic acid-d4) is the deuterium labeled 2-(1H-1,2,4-Triazol-1-yl)acetic acid (HY-W028914).
|
-
- HY-W456324
-
|
|
MOFs
|
Others
|
|
4,4'-(5'-(4-(4H-1,2,4-Triazol-4-yl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)bis(4H-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W075259
-
|
4-Amino-3,5-di-2-pyridyl-4H-1,2,4-triazole
|
MOFs
|
Others
|
|
3,5-Di(pyridin-2-yl)-4H-1,2,4-triazol-4-amine (4-Amino-3,5-di-2-pyridyl-4H-1,2,4-triazole) is a metal-organic framework (MOF).
|
-
- HY-W075616
-
|
4-[(3,5-Dipyridin-4-yl-1,2,4-triazol-1-yl)methyl]pyridine
|
MOFs
|
Others
|
|
4,4'-(1-(Pyridin-4-ylmethyl)-1H-1,2,4-triazole-3,5-diyl)dipyridine (4-[(3,5-Dipyridin-4-yl-1,2,4-triazol-1-yl)methyl]pyridine) is a metal-organic framework (MOF).
|
-
- HY-W074655
-
|
2-[4-[3,5-Bis[1-(carboxymethyl)triazol-4-yl]phenyl]triazol-1-yl]acetic acid
|
MOFs
|
Others
|
|
4,4′,4′′-(1,3,5-Benzenetriyl)tris[1H-1,2,3-triazole-1-acetic acid] (2-[4-[3,5-Bis[1-(carboxymethyl)triazol-4-yl]phenyl]triazol-1-yl]acetic acid) is a metal-organic framework (MOF).
|
-
- HY-W456314
-
|
2,2'-{Thiene-2,5-diylbis[(1H-1,2,4-triazole-5,3-diyl)]}dipyridine
|
MOFs
|
Others
|
|
2,5-Bis(5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thiophene (2,2'-{Thiene-2,5-diylbis[(1H-1,2,4-triazole-5,3-diyl)]}dipyridine) is a metal-organic framework (MOF).
|
-
- HY-Z7147
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate (Efinaconazole Impurity) is a biological molecule.
|
-
- HY-179587
-
|
|
PROTAC Linkers
|
Cancer
|
|
JQ-1 (carboxylic acid)-amine-PEG8-cyanogen is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-Y0219
-
|
s-triazole; Pyrrodiazole
|
Biochemical Assay Reagents
|
|
1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012991
-
|
|
Biochemical Assay Reagents
|
|
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007685
-
|
|
Biochemical Assay Reagents
|
|
Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y0219R
-
|
s-triazole (Standard); Pyrrodiazole (Standard)
|
Biochemical Assay Reagents
|
|
1,2,4-Triazole (Standard) is the analytical standard of 1,2,4-Triazole. This product is intended for research and analytical applications. 1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-107870
-
-
- HY-163789
-
|
|
Biochemical Assay Reagents
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-17514
-
|
R51211
|
Microorganisms
Source Classification
|
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
|
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-B0101R
-
|
UK-49858 (Standard)
|
Microorganisms
Source Classification
|
Reference Standards
Fungal
Antibiotic
Bacterial
|
|
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514R
-
|
R51211 (Standard)
|
Microorganisms
Source Classification
|
Reference Standards
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
|
Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-Y0688S
-
|
|
|
1H-Benzotriazole-4,5,6,7-d4 is the deuterium labeled 1H-Benzo[d][1,2,3]triazole .
|
-
-
- HY-14273S
-
|
|
|
Isavuconazole-d4 (BAL-4815-d4) is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi .
|
-
-
- HY-Y0219S1
-
|
|
|
NSC 83128-d3 is the deuterium labeled NSC 83128 .
|
-
-
- HY-141941S
-
|
|
|
Triazole Lactic Acid- 13C2, 15N3 is the 13C and 15N labeled Triazole Lactic Acid .
|
-
-
- HY-W098127S
-
|
|
|
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate .
|
-
-
- HY-141726S
-
|
|
|
rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3 is the deuterium labeled rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid .
|
-
-
- HY-W727488
-
|
|
|
2-(1H-1,2,4-Triazol-1-yl)acetic acid-d4 (1,2,4-Triazole-1-acetic acid-d4) is the deuterium labeled 2-(1H-1,2,4-Triazol-1-yl)acetic acid (HY-W028914).
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-163789
-
|
|
|
DBCO
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-141652
-
|
|
|
Azide
|
|
N-2-Azidoethyl betulonamide is the building block, that could generate cytotoxic triazole derivative through click chemistry .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-46369
-
|
|
|
Phosphoramidites
Uracil
|
|
1-p-Chlorobenzyl-1,2,3-triazole-5′-O-DMT-dU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
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