2. Anti-infection Metabolic Enzyme/Protease
  3. Fungal Cytochrome P450
  4. Isavuconazole-d4

Isavuconazole-d4  (Synonyms: BAL-4815-d4; RO-0094815-d4)

Cat. No.: HY-14273S Purity: 99.88%
COA Handling Instructions

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Isavuconazole-d4 is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi[1].

For research use only. We do not sell to patients.

Isavuconazole-d<sub>4</sub> Chemical Structure

Isavuconazole-d4 Chemical Structure

CAS No. : 1346598-58-0

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 605 In-stock
Solution
10 mM * 1 mL in DMSO USD 605 In-stock
Solid
1 mg USD 250 In-stock
5 mg USD 550 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Isavuconazole-d4:

Isavuconazole-d4 Related Antibodies

Top Publications Citing Use of Products

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP3A4 CYP17A1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Isavuconazole-d4 is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi[1].

Molecular Weight

441.49

Formula

C22H13D4F2N5OS
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

FC1=CC=C(F)C=C1[C@](CN2C=NC=N2)(O)[C@@H](C)C3=NC(C4=C([2H])C([2H])=C(C#N)C([2H])=C4[2H])=CS3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (226.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2651 mL 11.3253 mL 22.6506 mL
5 mM 0.4530 mL 2.2651 mL 4.5301 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2651 mL 11.3253 mL 22.6506 mL 56.6264 mL
5 mM 0.4530 mL 2.2651 mL 4.5301 mL 11.3253 mL
10 mM 0.2265 mL 1.1325 mL 2.2651 mL 5.6626 mL
15 mM 0.1510 mL 0.7550 mL 1.5100 mL 3.7751 mL
20 mM 0.1133 mL 0.5663 mL 1.1325 mL 2.8313 mL
25 mM 0.0906 mL 0.4530 mL 0.9060 mL 2.2651 mL
30 mM 0.0755 mL 0.3775 mL 0.7550 mL 1.8875 mL
40 mM 0.0566 mL 0.2831 mL 0.5663 mL 1.4157 mL
50 mM 0.0453 mL 0.2265 mL 0.4530 mL 1.1325 mL
60 mM 0.0378 mL 0.1888 mL 0.3775 mL 0.9438 mL
80 mM 0.0283 mL 0.1416 mL 0.2831 mL 0.7078 mL
100 mM 0.0227 mL 0.1133 mL 0.2265 mL 0.5663 mL
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Isavuconazole-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isavuconazole-d41346598-58-0BAL-4815-d4RO-0094815-d4FungalCytochrome P450CYPsdeuteriumtriazoleprodrugyeastsmoldsdimorphicfungiInhibitorinhibitorinhibit

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