1,2,3-Triazole-PEG8-amine
JQ-1 (carboxylic acid)-amine-PEG8-cyanogen is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Formula: C19H38N4O8
- Molecular Weight:450.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
BRD4 PROTACs contain two different ligands connected by a linker; one is an E3 ligase ligand (SJ1008066) (HY-149452), and the other is for Ligands of BRD4 target protein (JQ-1 (carboxylic acid)) (HY-78695). PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 450.53
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Formula C19H38N4O8
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SMILES
NCCOCCOCCOCCOCCOCCOCCOCCOCC1=CNN=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1,2,3-Triazole-PEG8-amine Related Classifications
HY-179587 Related Classifications
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