2. PROTAC
  3. PROTAC Linkers
  4. 1,2,3-Triazole-PEG8-amine

JQ-1 (carboxylic acid)-amine-PEG8-cyanogen is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

1,2,3-Triazole-PEG8-amine

1,2,3-Triazole-PEG8-amine Chemical Structure

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1,2,3-Triazole-PEG8-amine Related Antibodies

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Description

JQ-1 (carboxylic acid)-amine-PEG8-cyanogen is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

In Vitro

BRD4 PROTACs contain two different ligands connected by a linker; one is an E3 ligase ligand (SJ1008066) (HY-149452), and the other is for Ligands of BRD4 target protein (JQ-1 (carboxylic acid)) (HY-78695). PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1,2,3-Triazole-PEG8-amine Related Antibodies
Molecular Weight

450.53

Formula

C19H38N4O8
SMILES

NCCOCCOCCOCCOCCOCCOCCOCCOCC1=CNN=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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1,2,3-Triazole-PEG8-amine Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,2,3-Triazole-PEG8-aminePROTAC LinkersPROTACUbiquitin-proteasome systemUPSc-MycRUNX2KRT14Inhibitorinhibitorinhibit

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Product Name:
1,2,3-Triazole-PEG8-amine
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