MOR agonist-4
MOR agonist-4 (2d) is a G protein signaling-biased Kappa opioid receptor (KOR) agonist with an EC50 value of 11 nM. MOR agonist-4 contains an electron withdrawing CF3 group and a bias factor of 38 based on triazole. MOR agonist-4 is used in the research of pruritis and analgesia.
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- CAS No.: 3050669-97-8
- Formule: C22H19F3N4S
- Masse moléculaire:428.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
In Vitro
MOR agonist-4 (10 μM) completely inhibits U69,593 binding of an appropriate radiolabeled receptor ligand to KOR with a Ki value of 5.8 nM, but binding of ligands to MOR and DOR is poorly inhibited (30.9 % and 30.7 %, respectively)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3050669-97-8
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Masse moléculaire 428.47
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Formule C22H19F3N4S
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SMILES
CC(C=C1)=C(C(F)(F)F)C=C1CCC(N2CC3=CC=CS3)=NN=C2C4=CC=CC=N4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MOR agonist-4 Related Classifications
HY-161812 Related Classifications
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