1H-Benzotriazole-4,5,6,7-d₄

Cat. No.: HY-Y0688S Purity: 99.9%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

1H-Benzotriazole-4,5,6,7-d₄ is the deuterium labeled 1H-Benzo[d][1,2,3]triazole.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

1H-Benzotriazole-4,5,6,7-d₄ 화학구조

CAS No. : 1185072-03-0

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

1H-Benzotriazole-4,5,6,7-d₄ is the deuterium labeled 1H-Benzo[d][1,2,3]triazole^[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

123.15

화학식

C₆HD₄N₃

CAS No.

1185072-03-0

Unlabeled CAS

95-14-7

Appearance

Solid

Color

Off-white to light yellow

SMILES

[2H]C1=C2C(N=NN2)=C([2H])C([2H])=C1[2H]

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 100 mg/mL (812.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.1202 mL	40.6009 mL	81.2018 mL
5 mM	1.6240 mL	8.1202 mL	16.2404 mL
10 mM	0.8120 mL	4.0601 mL	8.1202 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.92%

Select Batch:

Data Sheet (274 KB) SDS (393 KB)

COA (253 KB) HNMR (161 KB) RP-HPLC (271 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	8.1202 mL	40.6009 mL	81.2018 mL	203.0045 mL
	5 mM	1.6240 mL	8.1202 mL	16.2404 mL	40.6009 mL
	10 mM	0.8120 mL	4.0601 mL	8.1202 mL	20.3004 mL
	15 mM	0.5413 mL	2.7067 mL	5.4135 mL	13.5336 mL
	20 mM	0.4060 mL	2.0300 mL	4.0601 mL	10.1502 mL
	25 mM	0.3248 mL	1.6240 mL	3.2481 mL	8.1202 mL
	30 mM	0.2707 mL	1.3534 mL	2.7067 mL	6.7668 mL
	40 mM	0.2030 mL	1.0150 mL	2.0300 mL	5.0751 mL
	50 mM	0.1624 mL	0.8120 mL	1.6240 mL	4.0601 mL
	60 mM	0.1353 mL	0.6767 mL	1.3534 mL	3.3834 mL
	80 mM	0.1015 mL	0.5075 mL	1.0150 mL	2.5376 mL
	100 mM	0.0812 mL	0.4060 mL	0.8120 mL	2.0300 mL