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Australian

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Antibiotic (2) Apoptosis (1) Bacterial (6) Endogenous Metabolite (3) Fungal (1) Herbicide (2) ICMT (1) Interleukin Related (1) Opioid Receptor (2) Wnt (1)
By Research Areas:	Cancer (8) Infection (8) Inflammation/Immunology (1) Neurological Disease (3)

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Recombinant Proteins

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-116479

Citromycetin	Bacterial	Others
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

HY-121133

(-)-Cyclopenol	Endogenous Metabolite	Others
(-)-Cyclopenol is a fungal metabolite isolated from an Australian marine-derived isolate of Aspergillus versicolor (MST-MF495) .

HY-N7171

4,4'-Di-O-methylellagic acid 4,4'-DiOMEA; Nasutin C	Wnt	Cancer
4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) can be isolated from the Australian termites. 4,4'-Di-O-methylellagic acid is blue-fluorescent under ultra-violet light . 4,4'-Di-O-methylellagic acid inhibits colon cancer cell proliferation via the wnt signal pathway .

HY-N10222

Roquefortine E	Others	Infection
Roquefortine E is a diketopiperazine from an Australian isolate of Gymnoascus reessii .

HY-N8552

Banksialactone A	Endogenous Metabolite	Infection
Banksialactone A is the metabolite of an Australian fungus, Aspergillus banksianus .

HY-122467

Kumbicin C	Bacterial	Infection Cancer
Kumbicin C is a bis-indolyl benzenoid compound from an Australian soil fungus, Aspergillus kumbius. Kumbicin C inhibits the growth of mouse myeloma cells and the Gram-positive bacterium Bacillus subtilis .

HY-P5728

Aurein 1.1	Bacterial Antibiotic	Infection
Aurein 1.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria raniformis .

HY-P5725

Aurein 2.1	Bacterial Antibiotic	Infection
Aurein 2.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria aurea and Litoria raniformis .

HY-W995439

Eduleine	Others	Others
Eduleine is an alkaloid found in Lunasia quercifolia in the Australian Rutaceae family. Eduleine is promising for research of antioxidants and enzyme inhibitors .

HY-N15322

Polyandric acid A	Interleukin Related	Inflammation/Immunology
Polyandric acid A is a clerodane diterpenoid that can be isolated from the Australian medicinal plant D. polyandra. Polyandric acid A attenuates pro-inflammatory cytokine secretion .

HY-149712

Spermatinamine	ICMT	Cancer
Spermatinamine is a novel alkaloid with a bromotyrosyl-spermine-bromotyrosyl sequence, and a natural ICMT inhibitor. Spermatinamine can be isolated from the Australian sponge Pseudoceratina .

HY-158702

5-HTQ chloride	5-HT Receptor	Neurological Disease
5-HTQ chloride is an indole alkaloid that can be isolated from the skin secretions of the Australian golden bell frog Litoria aurea. 5-HTQ chloride is also a full agonist of the 5-HT receptor .

HY-P4107

Bilaid C	Opioid Receptor	Neurological Disease
Bilaid C, a tetrapeptide, can be isolated from the Australian estuarine isolate of Penicillium sp. MST-MF667. Bilaid C is also a potent and selective μ-Opioid Receptor (MOPr) agonist (K_i=210 nM, hMOPr) .

HY-P3044

Bilaid A1e	Opioid Receptor	Neurological Disease
Bilaid A1e (Compound 1e) is a tetrapeptide agonist of the µ-opioid receptor (K_i = 750 nM). Bilaid A1e can be isolated from an Australian estuarine isolate of Penicillium sp. Bilaid A1e can be used for pain research .

HY-P5937

Caerin 1.1 TFA	Apoptosis	Cancer
Caerin 1.1 TFA is a host defense peptide isolated from the glandular secretions of the Australian tree frog Litoria. Caerin 1.1 TFA inhibits HeLa cell proliferation and mediates apoptosis. Caerin 1.1 TFA may enhance adaptive T cell immune responses .

HY-N19294

Hancockiamide A	Others	Cancer
Hancockiamide A is a compound found in the Australian soil fungus Aspergillus hancockii. Hancockiamide A inhibits tumor cell viability and inactivity against fibroblasts. Hancockiamide A can be used for the research of myeloma .

HY-W419221

Bixlozone	Herbicide	Others
Bixlozone, a proherbicide that requires in planta activation to its phytotoxic form, 5-ketobixlozone, is used to selectively control annual ryegrass (Lolium rigidum) in Australian cereal and canola crops. .

HY-N19313

Agelastatin D	Others	Cancer
Agelastatin D is a pyrrole-imidazole alkaloid and cytotoxic agent found in the Western Australian sponge Cymbastela sp.. Agelastatin D induces cytotoxic activity against cancer cells. Agelastatin D can be used for the research of chronic lymphocytic leukemia .

HY-N19290

Glenthmycin E	Bacterial	Infection
Glenthmycin E is an antibacterial agent found in Australian sheep pasture-derived Streptomyces sp. CMB-PB041. Glenthmycin E inhibits growth of multiple bacterial and exhibits no detectable cytotoxicity to eukaryotic cells including fungal and human carcinoma cells. Glenthmycin E can be used for the research of bacterial infections .

HY-172745

Conglobatin B1	Others	Cancer
Conglobatin B1 is a compound that can be isolated from Australian Streptomyces MST-91080. Conglobatin B1 is cytotoxic to the NS-1 myeloma cell line with an IC₅₀ of 0.084 μg/mL, but has low toxicity to NFF human fibroblasts. Conglobatin B1 can be used in the study of cancer .

HY-P11369

Pilosulin-1(86-112)	Bacterial	Infection Cancer
Pilosulin-1 (86-112) is a specific peptide segment of the Pilosulin 1 protein. Pilosulin 1 is the main allergen (Myr p 1) in the venom of Australian diving ants (Myrmecia pilosula), possessing potent cytotoxicity and antibacterial activity. Pilosulin-1 (86-112) is an IgE-binding component and is a secondary allergen .

HY-182489

Hancockiamide B	Fungal Endogenous Metabolite	Infection
Hancockiamide B (Compound 2) is a piperazine alkaloid. Hancockiamide B is isolated from the fungus Aspergillus hancockii .

HY-121139

Flupropanate 2,2,3,3-Tetrafluoropropionic acid; 3H-Tetrafluoropropionic acid	Herbicide	Others
Flupropanate (2,2,3,3-Tetrafluoropropionic acid; 3H-Tetrafluoropropionic acid) is a soil-active selective herbicide and plant growth inhibitor that acts by inhibiting radicle growth and lipid biosynthesis in sensitive plants. Flupropanate exhibits high-efficiency control of Stipa weeds (such as Nassella neesiana and N. trichotoma) in pastures, and reduces the coverage of the invasive species Eragrostis curvula. Meanwhile, Flupropanate is sensitive to gramineous plants like ryegrass, but shows good selective tolerance to plantain, chicory and some leguminous plants. Studies show that in the protected area with Mediterranean climate in southwestern Australia, Flupropanate produces no significant non-target effects on native plant communities, functional groups or the endangered species Grevillea curviloba, indicating high ecological safety .

Cat. No.	Nombre del producto	Target	Research Area

HY-P5728

Aurein 1.1	Bacterial Antibiotic	Infection
Aurein 1.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria raniformis .

HY-P5725

Aurein 2.1	Bacterial Antibiotic	Infection
Aurein 2.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria aurea and Litoria raniformis .

HY-P4107

Bilaid C	Opioid Receptor	Neurological Disease
Bilaid C, a tetrapeptide, can be isolated from the Australian estuarine isolate of Penicillium sp. MST-MF667. Bilaid C is also a potent and selective μ-Opioid Receptor (MOPr) agonist (K_i=210 nM, hMOPr) .

HY-P3044

Bilaid A1e	Opioid Receptor	Neurological Disease
Bilaid A1e (Compound 1e) is a tetrapeptide agonist of the µ-opioid receptor (K_i = 750 nM). Bilaid A1e can be isolated from an Australian estuarine isolate of Penicillium sp. Bilaid A1e can be used for pain research .

HY-P5937

Caerin 1.1 TFA	Apoptosis	Cancer
Caerin 1.1 TFA is a host defense peptide isolated from the glandular secretions of the Australian tree frog Litoria. Caerin 1.1 TFA inhibits HeLa cell proliferation and mediates apoptosis. Caerin 1.1 TFA may enhance adaptive T cell immune responses .

HY-P11369

Pilosulin-1(86-112)	Bacterial	Infection Cancer
Pilosulin-1 (86-112) is a specific peptide segment of the Pilosulin 1 protein. Pilosulin 1 is the main allergen (Myr p 1) in the venom of Australian diving ants (Myrmecia pilosula), possessing potent cytotoxicity and antibacterial activity. Pilosulin-1 (86-112) is an IgE-binding component and is a secondary allergen .

Citromycetin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Marine natural products Other Diseases Phenols Polyphenols Marine microorganism Disease Research Fields Source Classification	Bacterial
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

(-)-Cyclopenol	Alkaloids Microorganisms Classification of Application Fields Marine natural products Other Diseases Disease Research Fields Marine microorganism Source Classification	Endogenous Metabolite
(-)-Cyclopenol is a fungal metabolite isolated from an Australian marine-derived isolate of Aspergillus versicolor (MST-MF495) .

4,4'-Di-O-methylellagic acid 4,4'-DiOMEA; Nasutin C	Animals Phenols Polyphenols Source Classification	Wnt
4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) can be isolated from the Australian termites. 4,4'-Di-O-methylellagic acid is blue-fluorescent under ultra-violet light . 4,4'-Di-O-methylellagic acid inhibits colon cancer cell proliferation via the wnt signal pathway .

Roquefortine E	Infection Alkaloids Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Others
Roquefortine E is a diketopiperazine from an Australian isolate of Gymnoascus reessii .

Banksialactone A	Infection Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Phenols Disease Research Fields Source Classification	Endogenous Metabolite
Banksialactone A is the metabolite of an Australian fungus, Aspergillus banksianus .

Kumbicin C	Infection Alkaloids Microorganisms Classification of Application Fields Disease Research Fields Indole Alkaloids Source Classification	Bacterial
Kumbicin C is a bis-indolyl benzenoid compound from an Australian soil fungus, Aspergillus kumbius. Kumbicin C inhibits the growth of mouse myeloma cells and the Gram-positive bacterium Bacillus subtilis .

Eduleine	Alkaloids Other Alkaloids Rutaceae Plants Lunasia quercifolia Source Classification	Others
Eduleine is an alkaloid found in Lunasia quercifolia in the Australian Rutaceae family. Eduleine is promising for research of antioxidants and enzyme inhibitors .

Polyandric acid A	Ketones, Aldehydes, Acids Sapindaceae Plants Dodonaea polyandra Merr. & L.M.Perry Source Classification	Interleukin Related
Polyandric acid A is a clerodane diterpenoid that can be isolated from the Australian medicinal plant D. polyandra. Polyandric acid A attenuates pro-inflammatory cytokine secretion .

Hancockiamide A	Structural Classification Monophenols Microorganisms Phenols Source Classification	Others
Hancockiamide A is a compound found in the Australian soil fungus Aspergillus hancockii. Hancockiamide A inhibits tumor cell viability and inactivity against fibroblasts. Hancockiamide A can be used for the research of myeloma .

Agelastatin D	Structural Classification Productos naturales Animals Source Classification	Others
Agelastatin D is a pyrrole-imidazole alkaloid and cytotoxic agent found in the Western Australian sponge Cymbastela sp.. Agelastatin D induces cytotoxic activity against cancer cells. Agelastatin D can be used for the research of chronic lymphocytic leukemia .

Glenthmycin E	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Source Classification	Bacterial
Glenthmycin E is an antibacterial agent found in Australian sheep pasture-derived Streptomyces sp. CMB-PB041. Glenthmycin E inhibits growth of multiple bacterial and exhibits no detectable cytotoxicity to eukaryotic cells including fungal and human carcinoma cells. Glenthmycin E can be used for the research of bacterial infections .

Conglobatin B1	Productos naturales Microorganisms Source Classification	Others
Conglobatin B1 is a compound that can be isolated from Australian Streptomyces MST-91080. Conglobatin B1 is cytotoxic to the NS-1 myeloma cell line with an IC₅₀ of 0.084 μg/mL, but has low toxicity to NFF human fibroblasts. Conglobatin B1 can be used in the study of cancer .

Species:	Virus (2)
Tag:	His (2)
Source:	HEK293 (1) Sf9 insect cells (1)

Cat. No.	Compare	Nombre del producto	Species	Source	Image

HY-P77021

	HA/Hemagglutinin Protein, H15N2 (ABB90704, sf9, His) Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin / HA Protein (His)	Virus	Sf9 insect cells
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways. As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane. Hemagglutinin/HA Protein, H15N2 (ABB90704, sf9, His) is the recombinant Virus-derived Hemagglutinin/HA protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P74999

	HA1/Hemagglutinin Protein, H15N2 (ABB90704, HEK293, His) Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin Protein (HA1 Subunit) (His)	Virus	HEK293
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways.As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane.HA1/Hemagglutinin Protein, H15N2 (ABB90704, HEK293, His) is the recombinant Virus-derived HA1/Hemagglutinin protein, expressed by HEK293 , with C-His labeled tag.

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Australian

Inhibitors & Agonists

Peptides

NaturalProducts

Recombinant Proteins

Natural
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